Search Results - "Taylor, Angela"
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Mass spectrometry and immunoassay: how to measure steroid hormones today and tomorrow
Published in European journal of endocrinology (01-08-2015)“…SummaryThe recent onslaught of mass spectrometry (MS) to measurements of steroid hormones, including demands that they should be the only acceptable method,…”
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Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive review
Published in The Journal of steroid biochemistry and molecular biology (01-11-2019)“…[Display omitted] •The serum metabolome does not reflect steroids activated in an intracrine manner.•The urinary steroid metabolome reflects steroid…”
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11-oxygenated C19 steroids are the predominant androgens in polycystic ovary syndrome
Published in The journal of clinical endocrinology and metabolism (01-03-2017)“…Context:Androgen excess is a defining feature of polycystic ovary syndrome (PCOS) but the exact origin of hyperandrogenemia remains a matter of debate. Recent…”
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Prevention of Adrenal Crisis: Cortisol Responses to Major Stress Compared to Stress Dose Hydrocortisone Delivery
Published in The journal of clinical endocrinology and metabolism (01-07-2020)“…Abstract Context Patients with adrenal insufficiency require increased hydrocortisone cover during major stress to avoid a life-threatening adrenal crisis…”
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5
Characterizing the performance of high-speed data converters for RFSoC-based radio astronomy receivers
Published in Monthly notices of the Royal Astronomical Society (01-03-2021)“…ABSTRACT RF system-on-chip (RFSoC) devices provide the potential for implementing a complete radio astronomy receiver on a single board, but performance of the…”
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Human Monocyte Heterogeneity as Revealed by High-Dimensional Mass Cytometry
Published in Arteriosclerosis, thrombosis, and vascular biology (01-01-2019)“…OBJECTIVE—Three distinct human monocyte subsets have been identified based on the surface marker expression of CD14 and CD16. We hypothesized that monocytes…”
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Steroid metabolome analysis in disorders of adrenal steroid biosynthesis and metabolism
Published in Endocrine reviews (01-12-2019)“…Steroid biosynthesis and metabolism are reflected by the serum steroid metabolome and, in even more detail, by the 24-hour urine steroid metabolome, which can…”
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8
Morning vaccination enhances antibody response over afternoon vaccination: A cluster-randomised trial
Published in Vaccine (23-05-2016)“…Highlights • Early small studies provide mixed evidence for effects of time of vaccination on antibody response. • This is the first large scale randomised…”
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Single-Cell RNA Sequencing Reveals T Helper Cells Synthesizing Steroids De Novo to Contribute to Immune Homeostasis
Published in Cell reports (Cambridge) (22-05-2014)“…T helper 2 (Th2) cells regulate helminth infections, allergic disorders, tumor immunity, and pregnancy by secreting various cytokines. It is likely that there…”
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10
Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis
Published in Nature communications (15-03-2018)“…Regulatory T (Treg) cells contribute to the anti-inflammatory response during atherogenesis. Here we show that during atherogenesis Treg cells lose Foxp3…”
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Primary adrenal insufficiency is associated with impaired natural killer cell function: a potential link to increased mortality
Published in European journal of endocrinology (01-04-2017)“…Objective Mortality in patients with primary adrenal insufficiency (PAI) is significantly increased, with respiratory infections as a major cause of death…”
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12
Characterization of Foodborne Outbreaks of Salmonella enterica Serovar Enteritidis with Whole-Genome Sequencing Single Nucleotide Polymorphism-Based Analysis for Surveillance and Outbreak Detection
Published in Journal of clinical microbiology (01-10-2015)“…Salmonella enterica serovar Enteritidis is a significant cause of gastrointestinal illness in the United States; however, current molecular subtyping methods…”
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13
End-of-life experiences in individuals with dementia with Lewy bodies and their caregivers: A mixed-methods analysis
Published in PloS one (29-08-2024)“…Dementia with Lewy bodies (DLB) is one of the most common degenerative dementias, but research on end-of-life experiences for people with DLB and their…”
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AKR1C3-Mediated Adipose Androgen Generation Drives Lipotoxicity in Women With Polycystic Ovary Syndrome
Published in The journal of clinical endocrinology and metabolism (01-09-2017)“…Abstract Context Polycystic ovary syndrome (PCOS) is a prevalent metabolic disorder occurring in up to 10% of women of reproductive age. PCOS is associated…”
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Role of ALADIN in human adrenocortical cells for oxidative stress response and steroidogenesis
Published in PloS one (13-04-2015)“…Triple A syndrome is caused by mutations in AAAS encoding the protein ALADIN. We investigated the role of ALADIN in the human adrenocortical cell line…”
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Human Blood Monocyte Subsets: A New Gating Strategy Defined Using Cell Surface Markers Identified by Mass Cytometry
Published in Arteriosclerosis, thrombosis, and vascular biology (01-08-2017)“…OBJECTIVE—Human monocyte subsets are defined as classical (CD14CD16), intermediate (CD14CD16), and nonclassical (CD14CD16). Alterations in monocyte subset…”
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Salmonella enterica Serotype 4,[5],12:i:- in Swine in the United States Midwest: An Emerging Multidrug-Resistant Clade
Published in Clinical infectious diseases (05-03-2018)“…Salmonella 4,[5],12:i:-, a worldwide emerging pathogen that causes many food-borne outbreaks mostly attributed to pig and pig products, is expanding in the…”
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Using interpretative phenomenological analysis in a mixed methods research design to explore music in the lives of mature age amateur keyboard players
Published in Music education research (02-10-2015)“…This article discusses the use of interpretative phenomenological analysis (IPA) in a mixed methods research design with reference to five recent publications…”
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Alternative pathway androgen biosynthesis and human fetal female virilization
Published in Proceedings of the National Academy of Sciences - PNAS (29-10-2019)“…Androgen biosynthesis in the human fetus proceeds through the adrenal sex steroid precursor dehydroepiandrosterone, which is converted to testosterone in the…”
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Multi-steroid profiling by UHPLC-MS/MS with post-column infusion of ammonium fluoride
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-10-2022)“…•This multi-steroid profiling assay quantifies 25 steroids in 5.5 min.•Post-column infusion of NH4F enhances ionisation, especially of 3-keto-Δ4 steroids.•This…”
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