Search Results - "Tayama, Shunichi"

Fatty acid‐binding protein 3 regulates differentiation of IgM‐producing plasma cells by Kobayashi, Shuhei, Phung, Hai The, Tayama, Shunichi, Kagawa, Yoshiteru, Miyazaki, Hirofumi, Yamamoto, Yui, Maruyama, Takashi, Ishii, Naoto, Owada, Yuji

“…Plasma cells (PCs), which aim to protect host health, produce various subsets of immunoglobulin (Ig) in response to extracellular pathogens. Blimp‐1 (encoded…”
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Fatty acid-binding protein 5 limits ILC2-mediated allergic lung inflammation in a murine asthma model by Kobayashi, Shuhei, Tayama, Shunichi, Phung, Hai The, Kagawa, Yoshiteru, Miyazaki, Hirofumi, Takahashi, Yu, Maruyama, Takashi, Ishii, Naoto, Owada, Yuji

“…Dietary obesity is regarded as a problem worldwide, and it has been revealed the strong linkage between obesity and allergic inflammation. Fatty acid-binding…”
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Excess generation and activation of naturally arising memory-phenotype CD4 + T lymphocytes are inhibited by regulatory T cells in steady state by Li, Jing, Yang, Ziying, Kawajiri, Akihisa, Sato, Kosuke, Tayama, Shunichi, Ishii, Naoto, Zhu, Jinfang, Kawabe, Takeshi

“…Conventional CD4 T lymphocytes consist of naïve, foreign antigen-specific memory, and self-antigen-driven memory-phenotype (MP) cell compartments at…”
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Redefining the Foreign Antigen and Self-Driven Memory CD4 + T-Cell Compartments via Transcriptomic, Phenotypic, and Functional Analyses by Kawabe, Takeshi, Ciucci, Thomas, Kim, Kwang Soon, Tayama, Shunichi, Kawajiri, Akihisa, Suzuki, Takumi, Tanaka, Riou, Ishii, Naoto, Jankovic, Dragana, Zhu, Jinfang, Sprent, Jonathan, Bosselut, Rémy, Sher, Alan

“…Under steady-state conditions, conventional CD4 T lymphocytes are classically divided into naïve (CD44 CD62L ) and memory (CD44 CD62L ) cell compartments…”
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IQ motif-containing GTPase-activating protein 1 is essential for the optimal maintenance of lung ILC2s by Tayama, Shunichi, Okuyama, Yuko, Phung, Hai The, Asao, Atsuko, Kobayashi, Shuhei, Musha, Tomomi, Machiyama, Tomoaki, Sakurai, Tsuyoshi, Zhang, Chengming, Ushio-Fukai, Masuko, Kawabe, Takeshi, So, Takanori, Ishii, Naoto

“…Abstract Group 2 innate lymphoid cells (ILC2s) play critical roles in type 2 immunity and are crucial for pathogenesis of various types of inflammatory…”
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Correction: TRAF5 Deficiency Ameliorates the Severity of Dextran Sulfate Sodium Colitis by Decreasing TRAF2 Expression in Nonhematopoietic Cells by Phung, Hai The, Nagashima, Hiroyuki, Kobayashi, Shuhei, Asano, Naoki, Machiyama, Tomoaki, Sakurai, Tsuyoshi, Tayama, Shunichi, Asao, Atsuko, Imatani, Akira, Kawabe, Takeshi, Okuyama, Yuko, Ishii, Naoto, So, Takanori

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TRAF5 Deficiency Ameliorates the Severity of Dextran Sulfate Sodium Colitis by Decreasing TRAF2 Expression in Nonhematopoietic Cells by Phung, Hai The, Nagashima, Hiroyuki, Kobayashi, Shuhei, Asano, Naoki, Machiyama, Tomoaki, Sakurai, Tsuyoshi, Tayama, Shun-Ichi, Asao, Atsuko, Imatani, Akira, Kawabe, Takeshi, Okuyama, Yuko, Ishii, Naoto, So, Takanori

“…TNFR-associated factor 5 (TRAF5) is a cytosolic adaptor protein and functions as an inflammatory regulator. However, the in vivo function of TRAF5 remains…”
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Regulatory T cells tonically inhibit spontaneous activation of naturally arising memory-phenotype CD4+ T lymphocytes by Li, Jing, Yang, Ziying, Kawajiri, Akihisa, Sato, Kosuke, Tayama, Shunichi, Ishii, Naoto, Kawabe, Takeshi

“…Foxp3- CD4+ T lymphocytes consist of naïve (CD44lo), foreign antigen-specific memory, and self antigen-driven memory-phenotype (MP; both CD44hi) cells at…”
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Reactive persulfide controls intestinal inflammation by suppressing CD4 +T cell proliferation by Tayama, Shunichi, Kitamura, Yuya, Hiraide, Kyoga, Li, Jing, Yang, Ziying, Kawajiri, Akihisa, Sato, Kosuke, Okuyama, Yuko, Kawabe, Takeshi, Akaike, Takaaki, Ishii, Naoto

“…Inflammatory bowel disease (IBD) is characterized by chronic intestinal inflammation where CD4 +T lymphocytes play an essential role. Accumulating evidence…”
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CD127 and Sca1 mark self-driven memory-phenotype CD4 +T cells that differ from foreign antigen-specific memory cells and possess inflammatogenic and anti-tumor activities by Kawabe, Takeshi, Ciucci, Thomas, Kim, Kwang Soon, Yang, Ziying, Kawajiri, Akihisa, Tayama, Shunichi, Ishii, Naoto, Jankovic, Dragana, Zhu, Jinfang, Sprent, Jonathan, Bosselut, Remy, Sher, Alan

“…Under steady-state conditions, conventional CD4 +T lymphocytes are divided into naïve (CD44 loCD62L hi) and memory (CD44 hiCD62L lo) cell compartments. While…”
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Self antigen-driven, undifferentiated memory-phenotype CD4 T lymphocytes can induce mild and systemic inflammation by differentiating into effector and regulatory T cells by Kawajiri, Akihisa, Li, Jing, Yang, Ziying, Koinuma, Keita, Yoon, Hye Jin, Ishii, Minami, Tayama, Shunichi, Sato, Kosuke, Okuyama, Yuko, Harigae, Hideo, Ishii, Naoto, Ishigaki, Kazuyoshi, Zhu, Jinfang (Jeff), Kim, Kwang Soon, Kawabe, Takeshi

“…In adaptive immune responses, naïve CD4 +T lymphocytes that have T cell receptors (TCRs) reactive to challenged foreign antigens are activated to differentiate…”
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IQ motif-containing GTPase-activating protein 1 is essential for the optimal maintenance of lung ILC2s by Tayama, Shunichi, OKUYAMA, YUKO, PHUNG, HAI THE, ASAO, ATSUKO, KOBAYASHI, SHUHEI, KAWABE, TAKESHI, TAKANORI, SO, ISII, NAOTO

“…Group 2 innate lymphoid cells (ILC2s) play critical roles in type 2 immunity and are crucial for pathogenesis of various types of inflammatory disease. IQ…”
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