Search Results - "Tayal, Upasana"

Genetics and genomics of dilated cardiomyopathy and systolic heart failure by Tayal, Upasana, Prasad, Sanjay, Cook, Stuart A

“…Heart failure is a major health burden, affecting 40 million people globally. One of the main causes of systolic heart failure is dilated cardiomyopathy (DCM),…”
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Outcome in Dilated Cardiomyopathy Related to the Extent, Location, and Pattern of Late Gadolinium Enhancement by Halliday, Brian P., Baksi, A. John, Gulati, Ankur, Ali, Aamir, Newsome, Simon, Izgi, Cemil, Arzanauskaite, Monika, Lota, Amrit, Tayal, Upasana, Vassiliou, Vassilios S., Gregson, John, Alpendurada, Francisco, Frenneaux, Michael P., Cook, Stuart A., Cleland, John G.F., Pennell, Dudley J., Prasad, Sanjay K.

“…This study sought to investigate the association between the extent, location, and pattern of late gadolinium enhancement (LGE) and outcome in a large dilated…”
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Sex‐ and age‐based differences in the natural history and outcome of dilated cardiomyopathy by Halliday, Brian P., Gulati, Ankur, Ali, Aamir, Newsome, Simon, Lota, Amrit, Tayal, Upasana, Vassiliou, Vassilios S., Arzanauskaite, Monika, Izgi, Cemil, Krishnathasan, Kaushiga, Singhal, Arvind, Chiew, Kayla, Gregson, John, Frenneaux, Michael P., Cook, Stuart A., Pennell, Dudley J., Collins, Peter, Cleland, John G.F., Prasad, Sanjay K.

“…Aim To evaluate the relationship between sex, age and outcome in dilated cardiomyopathy (DCM). Methods and results We used proportional hazard modelling to…”
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Truncating Variants in Titin Independently Predict Early Arrhythmias in Patients With Dilated Cardiomyopathy by Tayal, Upasana, BMBCh, Newsome, Simon, MSc, Buchan, Rachel, MSc, Whiffin, Nicola, PhD, Walsh, Roddy, MSc, Barton, Paul J., PhD, Ware, James S., PhD, Cook, Stuart A., PhD, Prasad, Sanjay K., MD

“…Dilated cardiomyopathy (DCM) has a population prevalence of ~1 in 500 and is associated with prognostically adverse arrhythmias at initial disease presentation…”
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Phenotype and Clinical Outcomes of Titin Cardiomyopathy by Tayal, Upasana, Newsome, Simon, Buchan, Rachel, Whiffin, Nicola, Halliday, Brian, Lota, Amrit, Roberts, Angharad, Baksi, A. John, Voges, Inga, Midwinter, Will, Wilk, Alijca, Govind, Risha, Walsh, Roddy, Daubeney, Piers, Jarman, Julian W.E., Baruah, Resham, Frenneaux, Michael, Barton, Paul J., Pennell, Dudley, Ware, James S., Prasad, Sanjay K., Cook, Stuart A.

“…Improved understanding of dilated cardiomyopathy (DCM) due to titin truncation (TTNtv) may help guide patient stratification. The purpose of this study was to…”
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CardioClassifier: disease- and gene-specific computational decision support for clinical genome interpretation by Whiffin, Nicola, Walsh, Roddy, Govind, Risha, Edwards, Matthew, Ahmad, Mian, Zhang, Xiaolei, Tayal, Upasana, Buchan, Rachel, Midwinter, William, Wilk, Alicja E, Najgebauer, Hanna, Francis, Catherine, Wilkinson, Sam, Monk, Thomas, Brett, Laura, O’Regan, Declan P, Prasad, Sanjay K, Morris-Rosendahl, Deborah J, Barton, Paul J R, Edwards, Elizabeth, Ware, James S, Cook, Stuart A

“…Purpose Internationally adopted variant interpretation guidelines from the American College of Medical Genetics and Genomics (ACMG) are generic and require…”
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Myocardial remodelling and recovery in dilated cardiomyopathy by Tayal, Upasana, Prasad, Sanjay K

“…Myocardial reverse remodeling has been reported to occur in 25–70% of patients with dilated cardiomyopathy. It is not yet fully understood whether remodeling…”
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Clinical impact of re-evaluating genes and variants implicated in dilated cardiomyopathy by Stroeks, Sophie L. V. M., Hellebrekers, Debby M. E. I., Claes, Godelieve R. F., Tayal, Upasana, Krapels, Ingrid P. C., Vanhoutte, Els K., van den Wijngaard, Arthur, Henkens, Michiel T. H. M., Ware, James S., Heymans, Stephane R. B., Brunner, Han G., Verdonschot, Job A. J.

“…Purpose Accurate interpretation of variants detected in dilated cardiomyopathy (DCM) is crucial for patient care but has proven challenging. We applied a set…”
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Truncating Variants in Filamin C by Tayal, Upasana, MD, Cook, Stuart A., MD, PhD

“…Corresponding Author…”
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Arrhythmic Risk Stratification in Non-ischemic Cardiomyopathy Based on Cardiovascular Magnetic Resonance Measures of Myocardial Fibrosis and Gray Zone Fibrosis by Hammersley, Daniel, Zegard, Abbasin, Androulakis, Emmanuel, Jones, Richard, Okafor, Osita, Hatipoglu, Suzan, Mach, Lukas, Lota, Amrit, Khalique, Zohya, Marvao, Antonio De, Baruah, Resham, Guha, Kaushik, Ware, James, Tayal, Upasana, Pennell, Dudley, Halliday, Brian, Qiu, Tian, Prasad, Sanjay, Leyva, Francisco

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Direct and indirect effect of the COVID-19 pandemic on patients with cardiomyopathy by Hammersley, Daniel J, Buchan, Rachel J, Lota, Amrit S, Mach, Lukas, Jones, Richard E, Halliday, Brian P, Tayal, Upasana, Meena, Devendra, Dehghan, Abbas, Tzoulaki, Ioanna, Baksi, A John, Pantazis, Antonis, Roberts, Angharad M, Prasad, Sanjay K, Ware, James S

“…Objectives(1) To evaluate the prevalence and hospitalisation rate of COVID-19 infections among patients with dilated cardiomyopathy (DCM) and hypertrophic…”
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Asymptomatic Giant Coronary Artery Aneurysms by Tayal, Upasana, BM BCh, Elghamaz, Ahmed, MB, BCh

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The addition of genetic testing and cardiovascular magnetic resonance to routine clinical data for stratification of etiology in dilated cardiomyopathy by Amin, Ravi J, Morris-Rosendahl, Deborah, Edwards, Mat, Tayal, Upasana, Buchan, Rachel, Hammersley, Daniel J, Jones, Richard E, Gati, Sabiha, Khalique, Zohya, Almogheer, Batool, Pennell, Dudley J, Baksi, Arun John, Pantazis, Antonis, Ware, James S, Prasad, Sanjay K, Halliday, Brian P

“…Guidelines recommend genetic testing and cardiovascular magnetic resonance (CMR) for the investigation of dilated cardiomyopathy (DCM). However, the…”
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Changes in clinical and imaging variables during withdrawal of heart failure therapy in recovered dilated cardiomyopathy by Halliday, Brian P., Owen, Ruth, Gregson, John, Vazir, Ali, Wassall, Rebecca, Khalique, Zohya, Lota, Amrit S., Tayal, Upasana, Hammersley, Daniel J., Jones, Richard E., Pennell, Dudley J., Cowie, Martin R., Cleland, John G.F., Prasad, Sanjay K.

“…Aims This study aimed to profile the changes in non‐invasive clinical, biochemical, and imaging markers during withdrawal of therapy in patients with recovered…”
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Urinary drug metabolite testing in chronic heart failure patients indicates high levels of adherence with life‐prolonging therapies by Sweeney, Mark, Cole, Graham D., Pabari, Punam, Hadjiphilippou, Savvas, Tayal, Upasana, Mayet, Jamil, Chapman, Neil, Plymen, Carla M.

“…Aims Despite medical therapy for heart failure (HF) having proven benefits of improving quality of life and survival, many patients remain under‐treated. This…”
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Reproductive History Assessments in Cardiovascular Care: We Need to Start by Asking by Tayal, Paz (Upasana), Lala, Anuradha

“…[Display omitted]…”
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Genetic Testing for Dilated Cardiomyopathy by Lakdawala, Neal K., Tayal, Upasana

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Genetic Testing for Dilated Cardiomyopathy: Old School Is New School by Lakdawala, Neal K, Tayal, Upasana

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Aortic pulse wave velocity in obesity as assessed by magnetic resonance imaging by Rider, Oliver J, Tayal, Upasana, Francis, Jane M, Robinson, Monique, Byrne, James P, Clarke, Kieran, Neubauer, Stefan

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Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial by Halliday, Brian P, Wassall, Rebecca, Lota, Amrit S, Khalique, Zohya, Gregson, John, Newsome, Simon, Jackson, Robert, Rahneva, Tsveta, Wage, Rick, Smith, Gillian, Venneri, Lucia, Tayal, Upasana, Auger, Dominique, Midwinter, William, Whiffin, Nicola, Rajani, Ronak, Dungu, Jason N, Pantazis, Antonis, Cook, Stuart A, Ware, James S, Baksi, A John, Pennell, Dudley J, Rosen, Stuart D, Cowie, Martin R, Cleland, John G F, Prasad, Sanjay K

“…Patients with dilated cardiomyopathy whose symptoms and cardiac function have recovered often ask whether their medications can be stopped. The safety of…”
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