Search Results - "Tawfeek, Hesham M."
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Clinical translation of nanomedicines: Challenges, opportunities, and keys
Published in Advanced drug delivery reviews (01-02-2022)“…[Display omitted] Despite the massive interest and recent developments in the field of nanomedicine, only a limited number of formulations have found their way…”
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Biomedical Applications of Quantum Dots: Overview, Challenges, and Clinical Potential
Published in International journal of nanomedicine (01-05-2022)“…Despite the massive advancements in the nanomedicines and their associated research, their translation into clinically-applicable products is still below…”
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Different cellulosic polymers for synthesizing silver nanoparticles with antioxidant and antibacterial activities
Published in Scientific reports (08-01-2021)“…The use of cellulosic polymers as efficient reducing, coating agents, and stabilizers in the formulation of silver nanoparticles (AgNPs) with antioxidant and…”
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4
Antibacterial nanotruffles for treatment of intracellular bacterial infection
Published in Biomaterials (01-12-2020)“…Bacterial pathogens residing in host macrophages in intracellular infections are hard to eradicate because traditional antibiotics do not readily enter the…”
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Insight into the Inclusion Complexation of Fluconazole with Sulfonatocalix[4]naphthalene in Aqueous Solution, Solid-State, and Its Antimycotic Activity
Published in Molecules (Basel, Switzerland) (11-07-2022)“…The study aims to assess the interaction between fluconazole and sulfonatocalix[4]naphthalene towards enhancing its dissolution performance and antimycotic…”
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Enhancing the Low Oral Bioavailability of Sulpiride via Fast Orally Disintegrating Tablets: Formulation, Optimization and In Vivo Characterization
Published in Pharmaceuticals (Basel, Switzerland) (05-12-2020)“…Sulpiride (SUL) is a dopamine D -receptor antagonist used for management of GIT disturbance and it has anti-psychotic activities based on the administered…”
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Dissolution enhancement and formulation of rapid-release lornoxicam mini-tablets
Published in Journal of pharmaceutical sciences (01-08-2014)“…The aim was to enhance the dissolution of lornoxicam (LOR) and to produce mini-tablets with an optimised system to provide a rapid-release multi-particulate…”
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Silver Nanoparticles Stabilized by Poly (Vinyl Pyrrolidone) with Potential Anticancer Activity towards Prostate Cancer
Published in Bioinorganic chemistry and applications (2022)“…Tumor necrosis factor (TNF-α) and inflammatory cytokine (IL-6) play a vital role in various cellular incidents such as the proliferation and death of cells…”
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Transethosomal Gel for the Topical Delivery of Celecoxib: Formulation and Estimation of Skin Cancer Progression
Published in Pharmaceutics (21-12-2022)“…The topical delivery of therapeutics is a promising strategy for managing skin conditions. Cyclooxygenase-2 (COX-2) inhibitors showed a possible target for…”
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In Vitro Characterization of Inhalable Cationic Hybrid Nanoparticles as Potential Vaccine Carriers
Published in Pharmaceuticals (Basel, Switzerland) (18-02-2021)“…In this study, PGA-co-PDL nanoparticles (NPs) encapsulating model antigen, bovine serum albumin (BSA), were prepared via double emulsion solvent evaporation…”
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Somatostatin receptors as a new active targeting sites for nanoparticles
Published in Saudi pharmaceutical journal (01-11-2018)“…The delivery of nanoparticles through receptor-mediated cell interactions has nowadays a major attention in the area of drug targeting applications. This…”
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Utilizing Ziziphus spina-christi for eco-friendly synthesis of silver nanoparticles: Antimicrobial activity and promising application in wound healing
Published in Nanotechnology reviews (Berlin) (22-10-2024)“…Wound healing is a critical process essential for the body’s recovery from injuries, often complicated by bacterial infections. Silver nanoparticles (AgNPs)…”
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Studying the Complex Formation of Sulfonatocalix[4]naphthalene and Meloxicam towards Enhancing Its Solubility and Dissolution Performance
Published in Pharmaceutics (30-06-2021)“…The interaction between meloxicam and sulfonatocalix[4]naphthalene was investigated to improve the meloxicam solubility and its dissolution performance…”
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Can silver nanoparticles stabilized by Fenugreek ( Trigonella foenm -graecum ) improve tibial bone defects repair in rabbits? A preliminary study
Published in Open veterinary journal (Tripoli, Libya) (01-05-2024)“…A fracture is considered a medical emergency leading to considerable complications. This study aimed to describe the accelerating action of Ag-NPs-FG on…”
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Retardation of Bacterial Biofilm Formation by Coating Urinary Catheters with Metal Nanoparticle-Stabilized Polymers
Published in Microorganisms (Basel) (27-06-2022)“…Urinary catheter infections remain an issue for many patients and can complicate their health status, especially for individuals who require long-term…”
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Novel sublingual tablets of Atorvastatin calcium/Trimetazidine hydrochloride combination; HPTLC quantification, in vitro formulation and characterization
Published in Saudi pharmaceutical journal (01-05-2019)“…Ischemic heart disorders and accumulation of lipids in blood vessels could contribute to angina pectoris. Therefore, the aim of this study was to formulate…”
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Transfersomal Nanoparticles for Enhanced Transdermal Delivery of Clindamycin
Published in AAPS PharmSciTech (01-10-2016)“…ABSTRACT The aim of this work was to study the potential of delivering clindamycin phosphate, as an efficient antibiotic drug, into a more absorbed, elastic…”
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MCT4 knockdown by tumor microenvironment-responsive nanoparticles remodels the cytokine profile and eradicates aggressive breast cancer cells
Published in Colloids and surfaces, B, Biointerfaces (01-06-2024)“…Breast cancer is a wide-spread threat to the women’s health. The drawbacks of conventional treatments necessitate the development of alternative strategies,…”
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Effect of Spray Drying on Amorphization of Indomethacin Nicotinamide Cocrystals; Optimization, Characterization, and Stability Study
Published in AAPS PharmSciTech (30-06-2020)“…Cocrystals have gained a lot of consideration regarding its superior role in enhancement of solubility and dissolution of the included API. Cocrystals could be…”
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Nanomedicine as a future therapeutic approach for Hepatitis C virus
Published in Nanomedicine (London, England) (01-06-2019)“…Hepatitis C virus (HCV) is not easily cleared from the human body and in most cases turned into chronic infection. This chronicity is a major cause of liver…”
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