Search Results - "Tavarez, Urraca"

Biotinylation by antibody recognition—a method for proximity labeling by Bar, Daniel Z, Atkatsh, Kathleen, Tavarez, Urraca, Erdos, Michael R, Gruenbaum, Yosef, Collins, Francis S

“…Proximity-based labeling represents a useful approach for mapping protein environment, but current methods for this are limited to application to cell lines…”
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A targeted antisense therapeutic approach for Hutchinson–Gilford progeria syndrome by Erdos, Michael R., Cabral, Wayne A., Tavarez, Urraca L., Cao, Kan, Gvozdenovic-Jeremic, Jelena, Narisu, Narisu, Zerfas, Patricia M., Crumley, Stacy, Boku, Yoseph, Hanson, Gunnar, Mourich, Dan V., Kole, Ryszard, Eckhaus, Michael A., Gordon, Leslie B., Collins, Francis S.

“…Hutchinson–Gilford progeria syndrome (HGPS) is a rare accelerated aging disorder characterized by premature death from myocardial infarction or stroke. It is…”
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Genetic reduction of mTOR extends lifespan in a mouse model of Hutchinson‐Gilford Progeria syndrome by Cabral, Wayne A., Tavarez, Urraca L., Beeram, Indeevar, Yeritsyan, Diana, Boku, Yoseph D., Eckhaus, Michael A., Nazarian, Ara, Erdos, Michael R., Collins, Francis S.

“…Hutchinson‐Gilford progeria syndrome (HGPS) is a rare accelerated aging disorder most notably characterized by cardiovascular disease and premature death from…”
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Angiopoietin-2 reverses endothelial cell dysfunction in progeria vasculature by Vakili, Sahar, Izydore, Elizabeth K, Losert, Leonhard, Cabral, Wayne A, Tavarez, Urraca L, Shores, Kevin, Xue, Huijing, Erdos, Michael R, Truskey, George A, Collins, Francis S, Cao, Kan

“…Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder in children caused by a point mutation in the lamin A gene, resulting in a toxic…”
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Bone dysplasia in Hutchinson-Gilford progeria syndrome is associated with dysregulated differentiation and function of bone cell populations by Cabral, Wayne A, Stephan, Chris, Terajima, Masahiko, Thaivalappil, Abhirami A, Blanchard, Owen, Tavarez, Urraca L, Narisu, Narisu, Yan, Tingfen, Wincovitch, Stephen M, Taga, Yuki, Yamauchi, Mitsuo, Kozloff, Kenneth M, Erdos, Michael R, Collins, Francis S

“…Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disorder affecting tissues of mesenchymal origin. Most individuals with HGPS harbor a de novo…”
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farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model by Capell, Brian C, Olive, Michelle, Erdos, Michael R, Cao, Kan, Faddah, Dina A, Tavarez, Urraca L, Conneely, Karen N, Qu, Xuan, San, Hong, Ganesh, Santhi K, Chen, Xiaoyan, Avallone, Hedwig, Kolodgie, Frank D, Virmani, Renu, Nabel, Elizabeth G, Collins, Francis S

“…Hutchinson-Gilford progeria syndrome (HGPS) is the most dramatic form of human premature aging. Death occurs at a mean age of 13 years, usually from heart…”
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In vivo base editing rescues Hutchinson–Gilford progeria syndrome in mice by Koblan, Luke W., Erdos, Michael R., Wilson, Christopher, Cabral, Wayne A., Levy, Jonathan M., Xiong, Zheng-Mei, Tavarez, Urraca L., Davison, Lindsay M., Gete, Yantenew G., Mao, Xiaojing, Newby, Gregory A., Doherty, Sean P., Narisu, Narisu, Sheng, Quanhu, Krilow, Chad, Lin, Charles Y., Gordon, Leslie B., Cao, Kan, Collins, Francis S., Brown, Jonathan D., Liu, David R.

“…Hutchinson–Gilford progeria syndrome (HGPS or progeria) is typically caused by a dominant-negative C•G-to-T•A mutation (c.1824 C>T; p.G608G) in LMNA , the gene…”
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Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice by Kelada, Samir N P, Wilson, Mark S, Tavarez, Urraca, Kubalanza, Kari, Borate, Bhavesh, Whitehead, Greg S, Maruoka, Shuichiro, Roy, Michelle G, Olive, Michelle, Carpenter, Danielle E, Brass, David M, Wynn, Thomas A, Cook, Donald N, Evans, Christopher M, Schwartz, David A, Collins, Francis S

“…Asthma is etiologically and clinically heterogeneous, making the genomic basis of asthma difficult to identify. We exploited the strain-dependence of a murine…”
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Genetic analysis of hematological parameters in incipient lines of the collaborative cross by Kelada, Samir N P, Aylor, David L, Peck, Bailey C E, Ryan, Joseph F, Tavarez, Urraca, Buus, Ryan J, Miller, Darla R, Chesler, Elissa J, Threadgill, David W, Churchill, Gary A, Pardo-Manuel de Villena, Fernando, Collins, Francis S

“…Hematological parameters, including red and white blood cell counts and hemoglobin concentration, are widely used clinical indicators of health and disease…”
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Addendum: Biotinylation by antibody recognition—a method for proximity labeling by Bar, Daniel Z, Atkatsh, Kathleen, Tavarez, Urraca, Erdos, Michael R, Gruenbaum, Yosef, Collins, Francis S

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The genome architecture of the Collaborative Cross mouse genetic reference population by Cross Consortium, Collaborative

“…The Collaborative Cross Consortium reports here on the development of a unique genetic resource population. The Collaborative Cross (CC) is a multiparental…”
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