Search Results - "Tavares, T"
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Mercaptoacetamide: A promising zinc-binding group for the discovery of selective histone deacetylase 6 inhibitors
Published in European journal of medicinal chemistry (01-01-2021)“…Histone deacetylase 6 (HDAC6) is a zinc-dependent HDAC that mainly modulates the acetylation status of non-histone substrates, such as α-tubulin and heat shock…”
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Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot–Marie–Tooth Type 2A Mouse Model
Published in Journal of medicinal chemistry (22-04-2021)“…Histone deacetylase 6 (HDAC6) is a promising therapeutic target for the treatment of neurodegenerative disorders. SW-100 (1a), a phenylhydroxamate-based HDAC6…”
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Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models
Published in Journal of medicinal chemistry (24-09-2020)“…Selective inhibition of histone deacetylase 6 (HDAC6) is being recognized as a therapeutic approach for cancers. In this study, we designed a new HDAC6…”
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Invited review: physiological properties of bioactive peptides obtained from whey proteins
Published in Journal of dairy science (01-02-2010)“…Processing of whey proteins yields several bioactive peptides that can trigger physiological effects in the human body: on the nervous system via their opiate…”
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GelMA/bioactive silica nanocomposite bioinks for stem cell osteogenic differentiation
Published in Biofabrication (01-07-2021)“…Leveraging 3D bioprinting for processing stem cell-laden biomaterials has unlocked a tremendous potential for fabricating living 3D constructs for bone tissue…”
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6
Brazil oil spill response: Time for coordination
Published in Science (American Association for the Advancement of Science) (10-01-2020)Get full text
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Sustainable permeable biobarriers for atrazine removal in packed bed biofilm reactors
Published in Environmental pollution (1987) (01-02-2024)“…The synergy between two supported bacterial biofilms of S. equisimilis and P. putida and a sustainable biocarrier (raw pine) was studied, working both as…”
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Sustainable production of porous chitosan microparticles by energy-efficient membrane emulsification
Published in Heliyon (15-06-2024)“…In drug delivery, it is common to use porous particles as carrier media, instead of dense particles, due to their high specific surface area and available…”
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Topological Defects in Lattice Models and Affine Temperley–Lieb Algebra
Published in Communications in mathematical physics (01-06-2023)“…This paper is the first in a series where we attempt to define defects in critical lattice models that give rise to conformal field theory topological defects…”
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Preparation and In Vitro Characterization of Magnetic CS/PVA/HA/pSPIONs Scaffolds for Magnetic Hyperthermia and Bone Regeneration
Published in International journal of molecular sciences (06-01-2023)“…Conventional bone cancer treatment often results in unwanted side effects, critical-sized bone defects, and inefficient cancer-cell targeting. Therefore, new…”
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Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome
Published in ACS chemical neuroscience (20-03-2019)“…Disease-modifying therapies are needed for Fragile X Syndrome (FXS), as at present there are no effective treatments or cures. Herein, we report on a…”
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Chromium(III) biosorption onto spent grains residual from brewing industry: equilibrium, kinetics and column studies
Published in International journal of environmental science and technology (Tehran) (01-05-2015)“…The use of industrial wastes for wastewater treatment as a strategy to their re-use and valorisation may provide important advances toward sustainability. The…”
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Evaluation of Protein Kinase Inhibitors with PLK4 Cross-Over Potential in a Pre-Clinical Model of Cancer
Published in International journal of molecular sciences (29-04-2019)“…Polo-like kinase 4 (PLK4) is a cell cycle-regulated protein kinase (PK) recruited at the centrosome in dividing cells. Its overexpression triggers centrosome…”
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Sustainable strategies for nano-in-micro particle engineering for pulmonary delivery
Published in Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology (01-11-2014)“…With the increasing popularity and refinement of inhalation therapy, there has been a huge demand for the design and development of fine-tuned inhalable drug…”
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Grapefruit peelings as a promising biosorbent for the removal of leather dyes and hexavalent chromium
Published in Process safety and environmental protection (01-05-2016)“…•Grapefruit peeling is a good biosorbent for the removal of leather dyes and Cr(VI).•H2O2 pretreatment of grapefruit peeling enhanced its adsorption…”
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Novel eco-friendly biocatalyst: soybean peroxidase immobilized onto activated carbon obtained from agricultural waste
Published in RSC advances (01-01-2017)“…The immobilization of enzymes is an excellent alternative to overcome the drawbacks of using these biocatalysts in free form. This process plays a significant…”
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Mobility of Cr, Pb, Cd, Cu and Zn in a loamy sand soil: A comparative study
Published in Geoderma (15-09-2011)“…Interest in soil contamination has been growing in recent years due to the ongoing degradation of soil environments. Therefore, the development of remediation…”
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Application of zeolite- Arthrobacter viscosus system for the removal of heavy metal and dye: Chromium and Azure B
Published in Desalination (04-01-2012)“…A hybrid system combining the ion-exchange properties of a NaY zeolite and the characteristics of the bacterium Arthrobacter viscosus was investigated to treat…”
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Heterogeneous electro-Fenton treatment: preparation, characterization and performance in groundwater pesticide removal
Published in Journal of industrial and engineering chemistry (Seoul, Korea) (25-07-2015)“…In this work the preparation, characterization and performance of Y-zeolite as catalyst for electro-Fenton treatment of pesticides was carried out. Initially…”
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Development of permeable reactive biobarrier for the removal of PAHs by Trichoderma longibrachiatum
Published in Chemosphere (Oxford) (01-04-2013)“…► Innovative permeable reactive barrier using fungus biofilm was developed. ► Trichoderma longibrachiatum over nylon sponge was selected as the bioreactive…”
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