Search Results - "Tavares, L P"

Negative regulation of endothelin signaling by SIX1 is required for proper maxillary development by Tavares, Andre L P, Cox, Timothy C, Maxson, Robert M, Ford, Heide L, Clouthier, David E

“…Jaw morphogenesis is a complex event mediated by inductive signals that establish and maintain the distinct developmental domains required for formation of…”
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Editorial: Rising stars in inflammation 2021 by Baragetti, A, Suurmond, J, Marques, P E, Tavares, L P

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Six1 proteins with human branchio-oto-renal mutations differentially affect cranial gene expression and otic development by Shah, Ankita M, Krohn, Patrick, Baxi, Aparna B, Tavares, Andre L P, Sullivan, Charles H, Chillakuru, Yeshwant R, Majumdar, Himani D, Neilson, Karen M, Moody, Sally A

“…Single-nucleotide mutations in human result in amino acid substitutions in either the protein-protein interaction domain or the homeodomain, and cause ∼4% of…”
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Advances in Understanding the Pathogenesis of Craniofacial Birth Defects by Tavares, Andre L. P., Moody, Sally A.

“…Each year approximately 35% of babies are born with craniofacial abnormalities of the skull, jaws, ears, and/or teeth, which in turn can lead to problems in…”
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Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR) Differentially Affect Otic Expression of Putative Target Genes by Mehdizadeh, Tanya, Majumdar, Himani D, Ahsan, Sarah, Tavares, Andre L P, Moody, Sally A

“…Several single-nucleotide mutations in underlie branchio-otic/branchio-oto-renal (BOR) syndrome, but the clinical literature has not been able to correlate…”
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Zmym4 is required for early cranial gene expression and craniofacial cartilage formation by Jourdeuil, Karyn, Neilson, Karen M, Cousin, Helene, Tavares, Andre L P, Majumdar, Himani D, Alfandari, Dominique, Moody, Sally A

“…The Six1 transcription factor plays important roles in the development of cranial sensory organs, and point mutations underlie craniofacial birth defects…”
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Repressive Interactions Between Transcription Factors Separate Different Embryonic Ectodermal Domains by Klein, Steven L, Tavares, Andre L P, Peterson, Meredith, Sullivan, Charles H, Moody, Sally A

“…The embryonic ectoderm is composed of four domains: neural plate, neural crest, pre-placodal region (PPR) and epidermis. Their formation is initiated during…”
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The impact of technological endodontic resources on the training of the general dentist by Tavares, Érika P., Tavares, André L. P., Flório, Flávia M.

“…Introduction Technological resources are considered important for the practice and training in endodontics. It is not yet clear the extent of the insertion of…”
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Runx2‐I is an Early Regulator of Epithelial–Mesenchymal Cell Transition in the Chick Embryo by Tavares, Andre L.P., Brown, Jessie A., Ulrich, Emily C., Dvorak, Katerina, Runyan, Raymond B.

“…Background: Although normally linked to bone and cartilage development, the Runt‐related transcription factor, RUNX2, was reported in the mouse heart during…”
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Loss‐of‐function of Endothelin receptor type A results in Oro‐Oto‐Cardiac syndrome by Pritchard, Amanda Barone, Kanai, Stanley M., Krock, Bryan, Schindewolf, Erica, Oliver‐Krasinski, Jennifer, Khalek, Nahla, Okashah, Najeah, Lambert, Nevin A., Tavares, Andre L.P., Zackai, Elaine, Clouthier, David E.

“…Craniofacial morphogenesis is regulated in part by signaling from the Endothelin receptor type A (EDNRA). Pathogenic variants in EDNRA signaling pathway…”
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Understanding the basis of auriculocondylar syndrome: Insights from human, mouse and zebrafish genetic studies by Clouthier, David E., Passos-Bueno, Maria Rita, Tavares, Andre L.P., Lyonnet, Stanislas, Amiel, Jeanne, Gordon, Christopher T.

“…Among human birth defect syndromes, malformations affecting the face are perhaps the most striking due to cultural and psychological expectations of facial…”
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Nkx2.5 regulates endothelin converting enzyme‐1 during pharyngeal arch patterning by Iklé, Jennifer M., Tavares, Andre L. P., King, Marisol, Ding, Hailei, Colombo, Sophie, Firulli, Beth A., Firulli, Anthony B., Targoff, Kimara L., Yelon, Deborah, Clouthier, David E.

“…In gnathostomes, dorsoventral (D‐V) patterning of neural crest cells (NCC) within the pharyngeal arches is crucial for the development of hinged jaws. One of…”
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Collagen gel analysis of epithelial-mesenchymal transition in the embryo heart: An in vitro model system for the analysis of tissue interaction, signal transduction, and environmental effects by Lencinas, Alejandro, Tavares, André L. P., Barnett, Joey V., Runyan, Raymond B.

“…The cellular process of epithelial–mesenchymal cell transition (EMT) is a critical event in development that is reiterated in adult pathologies of metastasis…”
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Transcriptomic analysis reveals the role of SIX1 in mouse cranial neural crest patterning and bone development by Baxi, Aparna, Jourdeuil, Karyn, Cox, Timothy C, Clouthier, David E, Tavares, Andre L P

“…Genetic variants of the transcription factor SIX1 and its co-factor EYA1 underlie 50% of Branchio-oto-renal syndrome (BOR) cases. BOR is characterized by…”
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Sobp modulates the transcriptional activation of Six1 target genes and is required during craniofacial development by Tavares, Andre L P, Jourdeuil, Karyn, Neilson, Karen M, Majumdar, Himani D, Moody, Sally A

“…Branchio-oto-renal syndrome (BOR) is a disorder characterized by hearing loss, and craniofacial and/or renal defects. Variants in the transcription factor Six1…”
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Mcrs1 is required for branchial arch and cranial cartilage development by Keer, Stephanie, Cousin, Helene, Jourdeuil, Karyn, Neilson, Karen M., Tavares, Andre L.P., Alfandari, Dominique, Moody, Sally A.

“…Mcrs1 is a multifunctional protein that is critical for many cellular processes in a wide range of cell types. Previously, we showed that Mcrs1 binds to the…”
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Generation of a new six1‐null line in Xenopus tropicalis for study of development and congenital disease by Coppenrath, Kelsey, Tavares, Andre L. P., Shaidani, Nikko‐Ideen, Wlizla, Marcin, Moody, Sally A., Horb, Marko

“…Summary The vertebrate Six (Sine oculis homeobox) family of homeodomain transcription factors plays critical roles in the development of several organs. Six1…”
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Transcriptional dysregulation in developing trigeminal sensory neurons in the LgDel mouse model of DiGeorge 22q11.2 deletion syndrome by Maynard, Thomas M, Horvath, Anelia, P Bernot, James, Karpinski, Beverly A, Tavares, Andre L P, Shah, Ankita, Zheng, Qianqian, Spurr, Liam, Olender, Jacqueline, Moody, Sally A, Fraser, Claire M, LaMantia, Anthony-S, Lee, Norman H

“…Abstract LgDel mice, which model the heterozygous deletion of genes at human chromosome 22q11.2 associated with DiGeorge/22q11.2 deletion syndrome (22q11DS),…”
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Transcriptional dysregulation in developing trigeminal sensory neurons in the LgDel mouse model of DiGeorge 22q11.2 deletion syndrome by Maynard, Thomas M, Horvath, Anelia, Bernot, James P, Karpinski, Beverly A, Tavares, Andre L P, Shah, Ankita, Zheng, Qianqian, Spurr, Liam, Olender, Jacqueline, Moody, Sally A, Fraser, Claire M, LaMantia, Anthony-S, Lee, Norman H

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Cre recombinase-regulated Endothelin1 transgenic mouse lines: Novel tools for analysis of embryonic and adult disorders by Tavares, Andre L.P., Clouthier, David E.

“…Endothelin-1 (EDN1) influences both craniofacial and cardiovascular development and a number of adult physiological conditions by binding to one or both of the…”
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