Search Results - "Tavares, Elaine R."

Nanotechnology for the treatment of deep endometriosis: uptake of lipid core nanoparticles by LDL receptors in endometriotic foci by Bedin, Alessandra, Maranhão, Raul C, Tavares, Elaine R, Carvalho, Priscila O, Baracat, Edmund C, Podgaec, Sérgio

“…Rapidly dividing cells in multiple types of cancer and inflammatory diseases undergo high low density lipoprotein (LDL) uptake for membrane synthesis, and…”
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Influence of Drugs Carried in Lipid Nanoparticles in Coronary Disease of Rabbit Transplanted Heart by Barbieri, Lucas R., MD, Lourenço-Filho, Domingos D., MD, PhD, Tavares, Elaine R., PhD, Carvalho, Priscila O., PhD, Gutierrez, Paulo S., MD, PhD, Maranhão, Raul C., MD, PhD, Stolf, Noedir A.G., MD, PhD

“…Background Coronary allograft vasculopathy is an inflammatory-proliferative process that compromises the long-term success of heart transplantation and…”
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Anti-inflammatory effects of intravenous methotrexate associated with lipid nanoemulsions on antigen-induced arthritis by Mello, Suzana B V, Tavares, Elaine R, Guido, Maria Carolina, Bonfá, Eloisa, Maranhão, Raul C

“…To test the hypothesis that intravenous use of methotrexate associated with lipid nanoemulsions can achieve superior anti-inflammatory effects in the joints of…”
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An artificial nanoemulsion carrying paclitaxel decreases the transplant heart vascular disease: A study in a rabbit graft model by Lourenço-Filho, Domingos D., MD, PhD, Maranhão, Raul C., MD, PhD, Méndez-Contreras, Carlos A., MD, Tavares, Elaine R., BSci, Freitas, Fatima R., PhD, Stolf, Noedir A., MD, PhD

“…Objective In previous studies cholesterol-rich nanoemulsions (LDE) resembling low-density lipoprotein were shown to concentrate in atherosclerotic lesions of…”
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Lipid core nanoparticles as vehicle for docetaxel reduces atherosclerotic lesion, inflammation, cell death and proliferation in an atherosclerosis rabbit model by Meneghini, Bianca C., Tavares, Elaine R., Guido, Maria C., Tavoni, Thauany M., Stefani, Helio A., Kalil-Filho, Roberto, Maranhão, Raul C.

“…Chemotherapeutic agents used in cancer treatment associated to nanoparticles (LDE) that mimic the composition of low-density lipoprotein and buffer their…”
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mRNA levels of low-density lipoprotein receptors are overexpressed in the foci of deep bowel endometriosis by Gibran, Luciano, Maranhão, Raul C., Tavares, Elaine R., Carvalho, Priscila O., Abrão, Maurício S., Podgaec, Sergio

“…Abstract STUDY QUESTION Is mRNA expression of LDL receptors altered in deep bowel endometriotic foci? SUMMARY ANSWER mRNA expression of LDL receptors is…”
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Advances in non-invasive drug delivery for atherosclerotic heart disease by Maranhão, Raul C, Tavares, Elaine R

“…Apart from statins, anti-platelet agents and invasive procedures, the anti-atherosclerotic medical weaponry for coronary heart disease (CHD) is scarce and only…”
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The Expression of Lipoprotein Receptors Is Increased in the Infarcted Area After Myocardial Infarction Induced in Rats With Cardiac Dysfunction by de Lima, Aline D., Guido, Maria C., Tavares, Elaine R., Carvalho, Priscila O., Marques, Alyne F., de Melo, Marcelo D. T., Salemi, Vera M. C., Kalil‐Filho, Roberto, Maranhão, Raul C.

“…Left ventricular (LV) remodeling after myocardial infarction constitutes the structural basis for ventricular dysfunction and heart failure. The…”
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The Effects of Diabetes Induction on the Rat Heart: Differences in Oxidative Stress, Inflammatory Cells, and Fibrosis between Subendocardial and Interstitial Myocardial Areas by Salemi, Vera M. C., Tavares de Melo, Marcelo D., Tavares, Elaine R., Marques, Alyne F., Guido, Maria C., Maranhão, Raul Cavalcante

“…Diabetic cardiomyopathy (DCM) is characterized by cardiac remodeling and impaired diastolic function that may lead to heart failure. The aim of this study was…”
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Methotrexate carried in lipid core nanoparticles reduces myocardial infarction size and improves cardiac function in rats by Maranhão, Raul C, Guido, Maria C, de Lima, Aline D, Tavares, Elaine R, Marques, Alyne F, Tavares de Melo, Marcelo D, Nicolau, Jose C, Salemi, Vera Mc, Kalil-Filho, Roberto

“…Acute myocardial infarction (MI) is accompanied by myocardial inflammation, fibrosis, and ventricular remodeling that, when excessive or not properly…”
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Intra-articular methotrexate associated to lipid nanoemulsions: anti-inflammatory effect upon antigen-induced arthritis by Mello, Suzana B V, Tavares, Elaine R, Bulgarelli, Adriana, Bonfá, Eloisa, Maranhão, Raul C

“…Commercial methotrexate formulations (MTX) have poor anti-inflammatory action for intra-articular treatment of rheumatoid arthritis. Our aim was to investigate…”
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Use of Combined Chemotherapy with Etoposide and Methotrexate, both Associated to Lipid Nanoemulsions for Atherosclerosis Treatment in Cholesterol-fed Rabbits by Leite, Antonio C. A., Solano, Tatiana V., Tavares, Elaine R., Maranhão, Raul C.

“…Purpose Treatment of atherosclerotic rabbits with intravenous methotrexate or etoposide carried in lipid nanoemulsions (LDE) markedly reduced the lesions in…”
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Novel formulation of a methotrexate derivative with a lipid nanoemulsion by Moura, Juliana A, Valduga, Claudete J, Tavares, Elaine R, Kretzer, Iara F, Maria, Durvanei A, Maranhão, Raul C

“…Lipid nanoemulsions that bind to low-density lipoprotein receptors can concentrate chemotherapeutic agents in tissues with low-density lipoprotein receptor…”
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Effect of the Antioxidant Lipoic Acid in Aortic Phenotype in a Marfan Syndrome Mouse Model by Pereira Carramaschi, Lygia da Veiga, Laurindo, Francisco R. M., Takimura, Celso K., Nolasco, Patricia, Oliveira Silva, Thais Larissa Araújo de, Meirelles, Thayna, Tavares, Elaine R., Salemi, Vera M. C., Debbas, Victor, Guido, Maria C., Ferreira-Filho, Julio C. A.

“…Marfan syndrome (MFS) cardiovascular manifestations such as aortic aneurysms and cardiomyopathy carry substantial morbidity/mortality. We investigated the…”
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Paclitaxel associated with cholesterol-rich nanoemulsions promotes atherosclerosis regression in the rabbit by Maranhão, Raul C, Tavares, Elaine R, Padoveze, Amanda F, Valduga, Claudete J, Rodrigues, Debora G, Pereira, Maria D

“…Abstract A cholesterol-rich nanoemulsion (LDE) that resembles LDL binds to the LDL receptors and after injection into the blood stream may concentrate in cells…”
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Reduction of atherosclerotic lesions in rabbits treated with etoposide associated with cholesterol-rich nanoemulsions by Tavares, Elaine R, Freitas, Fatima R, Diament, Jayme, Maranhão, Raul C

“…Cholesterol-rich nanoemulsions (LDE) bind to low-density lipoprotein (LDL) receptors and after injection into the bloodstream concentrate in aortas of…”
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Abstract 13025: Methotrexate Carried in Lipid Core Nanoparticles Prevented the Dilation and Dissection of the Aortic Arch in Mice With Marfan Syndrome by Increasing the Bioavailability of Intracellular Adenosine by Guido, Maria Carolina, Lopes, Natalia M, Albuquerque, Camila I, Tavares, Elaine R, Jensen, Leonardo, Pereira, Lygia V, Laurindo, Francisco R, Maranhao, Raul C

“…IntroductionMutations in the fibrillin-1 gene result in aneurysms and rupture of the aorta, the main cause of mortality in patients with Marfan syndrome (MFS)…”
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Abstract 13994: Anti-cellular Proliferation Therapy Reduces Atherosclerotic Plaques and Vascular Inflammation in Experimental Hypercholesterolemia by Gomes, Fernando L, Maranhao, Raul C, Tavares, Elaine R, Oliveira, Priscila C, Machado, Thiago V, Soeiro, Alexandre M, Higuchi, Maria de Lourdes, Kalil-Filho, Roberto, Serrano, Carlos V

“…IntroductionThe lipid nanoemulsion (LDE) binds intensely to LDL receptors due to similarity in molecular composition. Anti-proliferative agents paclitaxel…”
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Abstract 11952: Daunorubicin Associated With Lipid Nanoparticles Reduces Inflammation and Aortic Lesions in an Atherosclerosis Rabbit Model by Albuquerque, Camila I, Tavares, Elaine R, Guido, Maria Carolina, Lopes, Natalia M, Vanalli Baroni, Roberta, Jensen, Leonardo, Araujo Silva, Bruna M, Kalil, Roberto, Tavoni, Thauany M, Maranhao, Raul C

“…IntroductionNanoparticles that resemble the lipid structure of LDL, named LDE, concentrates on sites with high cell proliferation rates, as in atherosclerotic…”
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Lipid Core Nanoparticles as Vehicle for Docetaxel Reduces Atherosclerotic Lesion, Inflammation, Cell Death and Proliferation in an Atherosclerosis Rabbit Model by Meneghini, Bianca C., Tavares, Elaine R., Guido, Maria C., Tavoni, Tauany M., Filho, Roberto Kallil, Maranhao, Raul C.

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