Search Results - "Tavakol‐Afshari, Jalil"
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A new generation of mesenchymal stromal/stem cells differentially trained by immunoregulatory probiotics in a lupus microenvironment
Published in Stem cell research & therapy (10-12-2023)“…Increasing evidence suggests that multipotent mesenchymal stem/stromal cells (MSCs) are a promising intervention strategy in treating autoimmune inflammatory…”
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Stimulating effect of nanocurcumin and crocin on proliferation and pluripotency of bone marrow-derived mesenchymal stem cells
Published in Iranian journal of basic medical sciences (01-01-2024)“…Enhancement of proliferation, pluripotency, and self-renewal capacity as the unique features of MSCs can improve their therapeutic potential to regenerate…”
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The potential role of miRNA in regulating macrophage polarization
Published in Heliyon (01-11-2023)“…Macrophage polarization is a dynamic process determining the outcome of various physiological and pathological situations through inducing pro-inflammatory…”
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Chromosomal Instability in Various Generations of Human Mesenchymal Stem Cells Following the Therapeutic Radiation
Published in Stem cells international (29-08-2023)“…Background. Radiotherapy is a crucial treatment for most malignancies. However, it can cause several side effects, including the development of secondary…”
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Efficacy analysis of hydroxychloroquine therapy in systemic lupus erythematosus: a study on disease activity and immunological biomarkers
Published in Inflammopharmacology (01-10-2018)“…Background Hydroxychloroquine (HCQ) is a widely prescribed medication to patients with systemic lupus erythematosus (SLE), with potential anti-inflammatory…”
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Are mesenchymal stem cells able to manage cytokine storm in COVID-19 patients? A review of recent studies
Published in Regenerative therapy (01-12-2021)“…The Covid-19 disease has recently become one of the biggest challenges globally, and there is still no specific medication. Findings showed the immune system…”
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Safety and efficacy of bone marrow derived-mesenchymal stem cells transplantation in patients with amyotrophic lateral sclerosis
Published in Regenerative therapy (01-12-2021)“…Stem cell-based treatments have emerged as potentially effective approaches to delay the progression of amyotrophic lateral sclerosis (ALS). This study was…”
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Specific Clinical and Immunological Changes Following Mesenchymal Stem Cell Transplantation in COVID-19-induced Acute Respiratory Distress Syndrome Patients: A Phase-I Clinical Trial
Published in Iranian journal of allergy, asthma, and immunology (01-12-2022)“…Acute respiratory distress syndrome (ARDS) is a systemic inflammation resulting from immune system overactivity. ARDS is also a fatal complication of COVID-19…”
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The impact of CYP19A1 variants and haplotypes on breast cancer risk, clinicopathological features and prognosis
Published in Molecular genetics & genomic medicine (01-07-2021)“…Background Different genetic variants in hormone‐regulating pathways have been identified to influence the risk of breast cancer. This study aimed to evaluate…”
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A significant increase in expression of FOXP3 and IL-17 genes in patients with allergic rhinitis underwent accelerated rush immunotherapy
Published in Iranian journal of basic medical sciences (01-09-2019)“…Allergic rhinitis (AR) is a common hypersensitivity disease worldwide. Immunotherapy has been performed as the best treatment for years. This study aimed to…”
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Cardioprotective microRNAs: Lessons from stem cell-derived exosomal microRNAs to treat cardiovascular disease
Published in Atherosclerosis (01-06-2019)“…The stem cell-based therapy has emerged as a promising therapeutic strategy for treating cardiovascular ischemic diseases (CVIDs), such as myocardial…”
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12
Novel selective Cox-2 inhibitors induce apoptosis in Caco-2 colorectal carcinoma cell line
Published in European journal of pharmaceutical sciences (20-11-2011)“…The cyclooxygenase-2 (COX-2) inhibitors including celecoxib inhibit cell growth and induce apoptosis in cancer cells. As COX-2 is over expressed in solid…”
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Interactions of mesenchymal stromal/stem cells and immune cells following MSC-based therapeutic approaches in rheumatoid arthritis
Published in Cellular immunology (01-11-2023)“…•Rheumatoid arthritis (RA) is a chronic autoimmune disorder involving joints and synovium due to dysregulated immune responses.•Mesenchymal stem cells (MSCs)…”
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Evaluation of serum interleukins-6, 8 and 10 levels as diagnostic markers of neonatal infection and possibility of mortality
Published in Iranian journal of basic medical sciences (01-12-2013)“…Bacterial infection contributes substantially to neonatal morbidity and mortality. Early diagnosis of neonatal sepsis is difficult because clinical signs are…”
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Therapeutic potential of mesenchymal stem cell-derived exosomes for allergic airway inflammation
Published in Cellular immunology (01-03-2024)“…•MSC-derived exosomes are nano-sized biological vesicles extensively administered in inflammatory disorders.•MSC-derived exosomes can implicated in allergic…”
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In Vivo Growth Inhibition of Human Caucasian Prostate Adenocarcinoma in Nude Mice Induced by Amygdalin with Metabolic Enzyme Combinations
Published in BioMed research international (21-05-2022)“…Cancer of the prostate is an indicated type that is often recorded as a kind of cancer in men and the second critical cause of mortality through cancer cases…”
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Anti‐inflammatory and immune‐modulatory impacts of berberine on activation of autoreactive T cells in autoimmune inflammation
Published in Journal of cellular and molecular medicine (01-12-2020)“…Autoreactive inflammatory CD4+ T cells, such as T helper (Th)1 and Th17 subtypes, have been found to associate with the pathogenesis of autoimmune disorders…”
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MicroRNA (miRNA) as a biomarker for diagnosis, prognosis, and therapeutics molecules in neurodegenerative disease
Published in Biomedicine & pharmacotherapy (01-08-2024)“…Neurodegenerative diseases that include Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), Huntington's disease (HD), and…”
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Dysregulated balance in Th17/Treg axis of Pristane-induced lupus mouse model, are mesenchymal stem cells therapeutic?
Published in International immunopharmacology (01-04-2023)“…This study investigated whether engraftment of MSCs helped prevent or alleviate the clinical course of SLE in a model of induced lupus by Pristane (as an…”
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Analysis of CFTR Gene Mutations in Children with Cystic Fibrosis, First Report from North-East of Iran
Published in Iranian journal of basic medical sciences (01-08-2013)“…More than 1500 registered mutations in cystic fibrosis transmembrane regulator (CFTR) gene are responsible for dysfunction of an ion channel protein and a wide…”
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