Search Results - "Tavakkoli, Armin D."
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Major contributors to FLASH sparing efficacy emerge from murine skin studies: dose rate, total dose per fraction, anesthesia and oxygenation
Published in Frontiers in oncology (25-10-2024)“…Normal tissue sparing from radiation damage upon ultra-high dose rate irradiation, known as the FLASH effect with an equivalent tumor response, has been widely…”
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Enhancement of Radiation Therapy through Blockade of the Immune Checkpoint, V-domain Ig Suppressor of T Cell Activation (VISTA), in Melanoma and Adenocarcinoma Murine Models
Published in International journal of molecular sciences (01-09-2023)“…Radiation therapy (RT) has recently demonstrated promise at stimulating an enhanced immune response. The recent success of immunotherapies, such as checkpoint…”
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Anesthetic Oxygen Use and Sex Are Critical Factors in the FLASH Sparing Effect
Published in Advances in radiation oncology (01-06-2024)“…Ultra High Dose-Rate (UHDR) radiation has been reported to spare normal tissue, compared with Conventional Dose-Rate (CDR) radiation. However, important work…”
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Porcine-human glioma xenograft model. Immunosuppression and model reproducibility
Published in Cancer treatment and research communications (2024)“…Glioblastoma is the most common primary malignant and treatment-resistant human brain tumor. Rodent models have played an important role in understanding brain…”
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Oxygen Consumption In Vivo by Ultra-High Dose Rate Electron Irradiation Depends Upon Baseline Tissue Oxygenation
Published in International journal of radiation oncology, biology, physics (24-10-2024)“…This study aimed to assess the impact of tissue oxygen levels on transient oxygen consumption induced by ultra-high dose rate (UHDR) electron radiation in…”
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Establishing connectivity through microdissections of midbrain stimulation-related neural circuits
Published in Brain (London, England : 1878) (03-09-2024)“…Comprehensive understanding of the neural circuits involving the ventral tegmental area is essential for elucidating the anatomofunctional mechanisms governing…”
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