Search Results - "Taussig, Ronald"

Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice by Potthoff, Matthew J, Potts, Austin, He, Tianteng, Duarte, João A G, Taussig, Ronald, Mangelsdorf, David J, Kliewer, Steven A, Burgess, Shawn C

“…Bile acid sequestrants are nonabsorbable resins designed to treat hypercholesterolemia by preventing ileal uptake of bile acids, thus increasing catabolism of…”
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The role of ventral striatal cAMP signaling in stress-induced behaviors by Plattner, Florian, Hayashi, Kanehiro, Hernández, Adan, Benavides, David R, Tassin, Tara C, Tan, Chunfeng, Day, Jonathan, Fina, Maggy W, Yuen, Eunice Y, Yan, Zhen, Goldberg, Matthew S, Nairn, Angus C, Greengard, Paul, Nestler, Eric J, Taussig, Ronald, Nishi, Akinori, Houslay, Miles D, Bibb, James A

“…Changes in cAMP signalling in the brain influence mood and responses to stress. Here, the authors found that Cdk5 regulates cAMP degradation by PDE4…”
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mechanism of cell death involving an adenylyl cyclase/PKA signaling pathway is induced by the Cry1Ab toxin of Bacillus thuringiensis by Zhang, X, Candas, M, Griko, N.B, Taussig, R, Bulla, L.A. Jr

“…Many pathogenic organisms and their toxins target host cell receptors, the consequence of which is altered signaling events that lead to aberrant activity or…”
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Use of a cAMP BRET Sensor to Characterize a Novel Regulation of cAMP by the Sphingosine 1-Phosphate/G13 Pathway by Jiang, Lily I., Collins, Julie, Davis, Richard, Lin, Keng-Mean, DeCamp, Dianne, Roach, Tamara, Hsueh, Robert, Rebres, Robert A., Ross, Elliott M., Taussig, Ronald, Fraser, Iain, Sternweis, Paul C.

“…Regulation of intracellular cyclic adenosine 3 ′,5 ′-monophosphate (cAMP) is integral in mediating cell growth, cell differentiation, and immune responses in…”
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Gain-of-Function Properties of a Dynamin 2 Mutant Implicated in Charcot-Marie-Tooth Disease by Tassin, Tara C, Barylko, Barbara, Hedde, Per Niklas, Chen, Yan, Binns, Derk D, James, Nicholas G, Mueller, Joachim D, Jameson, David M, Taussig, Ronald, Albanesi, Joseph P

“…Mutations in the gene encoding dynamin 2 (DNM2), a GTPase that catalyzes membrane constriction and fission, are associated with two autosomal-dominant motor…”
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A Novel Mechanism for Adenylyl Cyclase Inhibition from the Crystal Structure of Its Complex with Catechol Estrogen by Steegborn, Clemens, Litvin, Tatiana N., Hess, Kenneth C., Capper, Austin B., Taussig, Ronald, Buck, Jochen, Levin, Lonny R., Wu, Hao

“…Catechol estrogens are steroid metabolites that elicit physiological responses through binding to a variety of cellular targets. We show here that catechol…”
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Raf kinase activation of adenylyl cyclases: isoform-selective regulation by Ding, Qingming, Gros, Robert, Gray, Ian D, Taussig, Ronald, Ferguson, Stephen S G, Feldman, Ross D

“…Adenylyl cyclases (AC), a family of enzymes that catalyze the synthesis of cyclic AMP, are critical regulators of cellular functions. The activity of adenylyl…”
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Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel by Wickman, Kevin D, Iñiguez-Lluhi, Jorge A, Davenport, Philip A, Taussig, Ronald, Krapivinsky, Grigory B, Linder, Maurine E, Gilman, Alfred G, Clapham, David E

“…Acetylcholine activates inwardly rectifying potassium channels (IK.ACh) in the heart through muscarinic receptor binding and activation of…”
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Mutations Uncover a Role for Two Magnesium Ions in the Catalytic Mechanism of Adenylyl Cyclase by Zimmermann, Gregor, Zhou, Dongmei, Taussig, Ronald

“…The recent determination of the crystal structure of adenylyl cyclase has elucidated many structural features that determine the regulatory properties of the…”
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Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases by Park, Sung-Jun, Ahmad, Faiyaz, Philp, Andrew, Baar, Keith, Williams, Tishan, Luo, Haibin, Ke, Hengming, Rehmann, Holger, Taussig, Ronald, Brown, Alexandra L, Kim, Myung K, Beaven, Michael A, Burgin, Alex B, Manganiello, Vincent, Chung, Jay H

“…Doc number: P73…”
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Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases by Park, Sung-Jun, Ahmad, Faiyaz, Philp, Andrew, Baar, Keith, Williams, Tishan, Luo, Haibin, Ke, Hengming, Rehmann, Holger, Taussig, Ronald, Brown, Alexandra L., Kim, Myung K., Beaven, Michael A., Burgin, Alex B., Manganiello, Vincent, Chung, Jay H.

“…Resveratrol, a polyphenol in red wine, has been reported as a calorie restriction mimetic with potential antiaging and antidiabetogenic properties. It is…”
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Activating mutation of adenylyl cyclase reverses its inhibition by G proteins by Zimmermann, G, Zhou, D, Taussig, R

“…We have implemented a yeast genetic selection developed previously by our laboratory to identify mutant mammalian type V adenylyl cyclases insensitive to…”
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Isozyme-dependent Sensitivity of Adenylyl Cyclases to P-site-mediated Inhibition by Adenine Nucleosides and Nucleoside 3′-Polyphosphates by Johnson, Roger A., Désaubry, Laurent, Bianchi, Glen, Shoshani, Ilana, Lyons, Edward, Taussig, Ronald, Watson, Peter A., Cali, James J., Krupinski, John, Pieroni, Joseph P., Iyengar, Ravi

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Protein Kinase C Alters the Responsiveness of Adenylyl Cyclases to G Protein α and βγ Subunits by Zimmermann, Gregor, Taussig, Ronald

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Assays of recombinant adenylyl cyclases expressed in Sf9 cells by Taussig, Ronald

“…This chapter outlines procedures for the expression of mammalian membrane-bound adenylyl cyclases (AC) in Sf9 cells and subsequent in vitro methods for…”
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Mammalian Membrane-bound Adenylyl Cyclases (∗) by Taussig, Ronald, Gilman, Alfred G.

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Deciphering signaling outcomes from a system of complex networks by Hsueh, Robert C, Natarajan, Madhusudan, Fraser, Iain, Pond, Blake, Liu, Jamie, Mumby, Susanne, Han, Heping, Jiang, Lily I, Simon, Melvin I, Taussig, Ronald, Sternweis, Paul C

“…Cellular signal transduction machinery integrates information from multiple inputs to actuate discrete cellular behaviors. Interaction complexity exists when…”
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Inhibition of Adenylyl Cyclase by G$_{i\alpha} by Taussig, Ronald, Iñiguez-Lluhi, Jorge A., Gilman, Alfred G.

“…Evidence suggests that both α and βγ subunits of heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins) inhibit adenylyl cyclase. Although…”
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Overview of the Alliance for Cellular Signaling by Gilman, Alfred G, Simon, Melvin I, Bourne, Henry R, Harris, Bruce A, Long, Rochelle, Ross, Elliott M, Stull, James T, Taussig, Ronald, Arkin, Adam P, Cobb, Melanie H, Cyster, Jason G, Devreotes, Peter N, Ferrell, James E, Fruman, David, Gold, Michael, Weiss, Arthur, Berridge, Michael J, Cantley, Lewis C, Catterall, William A, Coughlin, Shaun R, Olson, Eric N, Smith, Temple F, Brugge, Joan S, Botstein, David, Dixon, Jack E, Hunter, Tony, Lefkowitz, Robert J, Pawson, Anthony J, Sternberg, Paul W, Varmus, Harold, Subramaniam, Shankar, Sinkovits, Robert S, Li, Joshua, Mock, Dennis, Ning, Yuhong, Saunders, Brian, Sternweis, Paul C, Hilgemann, Donald, Scheuermann, Richard H, DeCamp, Dianne, Hsueh, Robert, Lin, Keng-Mean, Ni, Yan, Seaman, William E, Simpson, Paul C, O'Connell, Timothy D, Roach, Tamara, Choi, Sangdun, Eversole-Cire, Pamela, Fraser, Iain, Mumby, Marc C, Zhao, Yingming, Brekken, Deirdre, Shu, Hongjun, Meyer, Tobias, Chandy, Grischa, Heo, Won Do, Liou, Jen, O'Rourke, Nancy, Verghese, Mary, Mumby, Susanne M, Han, Heping, Brown, H Alex, Forrester, Jeffrey S, Ivanova, Pavlina, Milne, Stephen B, Casey, Patrick J, Harden, T Kendall, Doyle, John, Gray, Martha L, Michnick, Stephen, Schmidt, Martin A, Toner, Mehmet, Tsien, Roger Y, Natarajan, Madhusudan, Ranganathan, Rama, Sambrano, Gilberto R

“…The Alliance for Cellular Signaling is a large-scale collaboration designed to answer global questions about signalling networks. Pathways will be studied…”
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G protein-coupled receptor-mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness by Dbouk, Hashem A, Vadas, Oscar, Shymanets, Aliaksei, Burke, John E, Salamon, Rachel S, Khalil, Bassem D, Barrett, Mathew O, Waldo, Gary L, Surve, Chinmay, Hsueh, Christine, Perisic, Olga, Harteneck, Christian, Shepherd, Peter R, Harden, T Kendall, Smrcka, Alan V, Taussig, Ronald, Bresnick, Anne R, Nürnberg, Bernd, Williams, Roger L, Backer, Jonathan M

“…Synergistic activation by heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors (GPCRs) and receptor tyrosine kinases distinguishes…”
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