Search Results - "Taubner, Lara M"

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  1. 1

    Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays by Wilham, Jason M, Orrú, Christina D, Bessen, Richard A, Atarashi, Ryuichiro, Sano, Kazunori, Race, Brent, Meade-White, Kimberly D, Taubner, Lara M, Timmes, Andrew, Caughey, Byron

    Published in PLoS pathogens (01-12-2010)
    “…A major problem for the effective diagnosis and management of prion diseases is the lack of rapid high-throughput assays to measure low levels of prions. Such…”
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    Journal Article
  2. 2

    Structure of the Flexible Amino-Terminal Domain of Prion Protein Bound to a Sulfated Glycan by Taubner, Lara M., Bienkiewicz, Ewa A., Copié, Valérie, Caughey, Byron

    Published in Journal of molecular biology (22-01-2010)
    “…The intrinsically disordered amino-proximal domain of hamster prion protein (PrP) contains four copies of a highly conserved octapeptide sequence, PHGGGWGQ,…”
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    Journal Article
  3. 3

    Parallel In-register Intermolecular β-Sheet Architectures for Prion-seeded Prion Protein (PrP) Amyloids by Groveman, Bradley R., Dolan, Michael A., Taubner, Lara M., Kraus, Allison, Wickner, Reed B., Caughey, Byron

    Published in The Journal of biological chemistry (29-08-2014)
    “…Structures of the infectious form of prion protein (e.g. PrPSc or PrP-Scrapie) remain poorly defined. The prevalent structural models of PrPSc retain most of…”
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    Journal Article
  4. 4

    Prion protein misfolding and disease by Moore, Roger A, Taubner, Lara M, Priola, Suzette A

    Published in Current opinion in structural biology (01-02-2009)
    “…Transmissible spongiform encephalopathies (TSEs or prion diseases) are a rare group of invariably fatal neurodegenerative disorders that affect humans and…”
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  5. 5

    Structural Studies of Apo Nosl, an Accessory Protein of the Nitrous Oxide Reductase System:  Insights from Structural Homology with MerB, a Mercury Resistance Protein by Taubner, Lara M, McGuirl, Michele A, Dooley, David M, Copié, Valérie

    Published in Biochemistry (Easton) (10-10-2006)
    “…The formation of the unique catalytic tetranuclear copper cluster (CuZ) of nitrous oxide reductase, N2OR, requires the coexpression of a multiprotein assembly…”
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  6. 6

    Rapid End-Point Quantitation of Prion Seeding Activity with Sensitivity Comparable to Bioassays: e1001217 by Wilham, Jason M, Orrú, Christina D, Bessen, Richard A, Atarashi, Ryuichiro, Sano, Kazunori, Race, Brent, Meade-White, Kimberly D, Taubner, Lara M, Timmes, Andrew, Caughey, Byron

    Published in PLoS pathogens (01-12-2010)
    “…A major problem for the effective diagnosis and management of prion diseases is the lack of rapid high-throughput assays to measure low levels of prions. Such…”
    Get full text
    Journal Article
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    Efficient method for the t-butyldimethylsilylation of alcohols with N, O-bis( t-butyldimethylsilyl)acetamide by Johnson, David A., Taubner, Lara M.

    Published in Tetrahedron letters (29-01-1996)
    “…The efficient t-butyldimethylsilylation of alcohols—including tertiary and sterically hindered secondary alcohols—can be achieved using N, O-bis(…”
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    Journal Article