Search Results - "Tatyana V. Volkova"

Permeability of New Antifungal Fluconazole Derivatives through a Lipophilic Membrane: Experiment and Modeling by Volkova, Tatyana V, Perlovich, German L

“…Relationships between the structures of molecules and their properties form the basis of modern chemistry and lay the foundation for structure-based drug…”
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Cocrystal formation, crystal structure, solubility and permeability studies for novel 1,2,4-thiadiazole derivative as a potent neuroprotector by Surov, Artem O., Volkova, Tatyana V., Churakov, Andrei V., Proshin, Alexey N., Terekhova, Irina V., Perlovich, German L.

“…The cocrystallization approach has been applied to modify the poor solubility profile of the biologically active 1,2,4-thiadiazole derivative (TDZ). Extensive…”
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New Antifungal Compound: Impact of Cosolvency, Micellization and Complexation on Solubility and Permeability Processes by Volkova, Tatyana V., Simonova, Olga R., Perlovich, German L.

“…Poor solubility of new antifungal of 1,2,4-triazole class (S-119)—a structural analogue of fluconazole in aqueous media was estimated. The solubility…”
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Another Move towards Bicalutamide Dissolution and Permeability Improvement with Acetylated β-Cyclodextrin Solid Dispersion by Volkova, Tatyana V., Simonova, Olga R., Perlovich, German L.

“…The complex formation of antiandrogen bicalutamide (BCL) with methylated (Me-β-CD) and acetylated (Ac-β-CD) β-cyclodextrins was investigated in buffer solution…”
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Features of the local structure and transport properties of ZrO2-Y2O3-Eu2O3 solid solutions by Borik, Mikhail A., Volkova, Tatyana V., Kuritsyna, Irina E., Lomonova, Elena E., Myzina, Valentina A., Ryabochkina, Polina A., Tabachkova, Nataliya Yu

“…The features of the local crystal structure for the series of the (ZrO2)1-х-у(Y2O3)х(Eu2O3)y (x = 0.027–0.38; y = 0.001; 0.005) solid solutions with different…”
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Physicochemical Profile of Antiandrogen Drug Bicalutamide: Solubility, Distribution, Permeability by Volkova, Tatyana V, Simonova, Olga R, Perlovich, German L

“…The pharmacologically relevant physicochemical properties of the antiandrogen drug bicalutamide (BCL) have been determined for the first time. Solubility in…”
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Understanding of Relationship between Phospholipid Membrane Permeability and Self-Diffusion Coefficients of Some Drugs and Biologically Active Compounds in Model Solvents by Blokhina, Svetlana V, Volkova, Tatyana V, Golubev, Vasiliy A, Perlovich, German L

“…In this work we measured self-diffusion coefficients of 5 drugs (aspirin, caffeine, ethionamide, salicylic acid, and paracetamol) and 11 biologically active…”
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Formation Thermodynamics of Carbamazepine with Benzamide, Para-Hydroxybenzamide and Isonicotinamide Cocrystals: Experimental and Theoretical Study by Manin, Alex N, Boycov, Denis E, Simonova, Olga R, Volkova, Tatyana V, Churakov, Andrei V, Perlovich, German L

“…Formation thermodynamic parameters for three cocrystals of carbamazepine (CBZ) with structurally related coformers (benzamide (BZA), para-hydroxybenzamide…”
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Chiral Recognition R- and RS- of New Antifungal: Complexation/Solubilization/Dissolution Thermodynamics and Permeability Assay by Volkova, Tatyana V, Simonova, Olga R, Levshin, Igor B, Perlovich, German L

“…Novel potential antifungal of 1,2,4-triazole class have been synthesized as pure enantiomer (R-98) and racemic (RS-186). The effect of…”
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Towards an understanding of the molecular mechanism of solvation of drug molecules: a thermodynamic approach by crystal lattice energy, sublimation, and solubility exemplified by paracetamol, acetanilide, and phenacetin by Perlovich, German L, Volkova, Tatyana V, Bauer-Brandl, Annette

“…Temperature dependencies of saturated vapor pressure for the monoclinic modification of paracetamol (acetaminophen), acetanilide, and phenacetin…”
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Comparative analysis of solubilization and complexation characteristics for new antifungal compound with cyclodextrins. Impact of cyclodextrins on distribution process by Volkova, Tatyana V., Perlovich, German L.

“…•Solubility of new antifungal compound in three cyclodextrins at pH 2.0 and pH 7.4 was studied by phase-solubility method in temperature range 298-313.15…”
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Novel Isothiourea Derivatives as Potent Neuroprotectors and Cognition Enhancers: Synthesis, Biological and Physicochemical Properties by Perlovich, German L, Proshin, Alexey N, Volkova, Tatyana V, Kurkov, Sergey V, Grigoriev, Vlaimir V, Petrova, Ludmila N, Bachurin, Sergey O

“…Various salts of 3-allyl-1,1-dibenzyl-2-ethyl-isothiourea, 1 (hydrochloride), 2 (hydrobromide), and 3 (hydroiodide), were synthesized. Ca-blocking properties…”
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Permeability of diverse drugs through a lipid barrier: Impact of pH and cyclodextrin by Volkova, Tatyana V., Simonova, Olga R., Perlovich, German L.

“…[Display omitted] •Permeability of 34 diverse drug compounds through the PermeaPad was determined.•Reliable permeability correlations in the framework of the…”
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Extending the Range of Nitrofurantoin Solid Forms: Effect of Molecular and Crystal Structure on Formation Thermodynamics and Physicochemical Properties by Surov, Artem O, Voronin, Alexander P, Drozd, Ksenia V, Volkova, Tatyana V, Vasilev, Nikita, Batov, Dmitriy, Churakov, Andrei V, Perlovich, German L

“…In this work, four novel pharmaceutical cocrystals of nitrofurantoin, an antibacterial drug, with isonicotinamide, picolinamide, 2-hydroxybenzamide, and…”
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Effect of the ionic radius of stabilizing oxide cation on the local structure and transport properties of zirconia based solid solutions by Artemov, Sergey A., Borik, Mikhail A., Kulebyakin, Alexey V., Kuritsyna, Irina E., Larina, Nataliya A., Lomonova, Elena E., Myzina, Valentina A., Ryabochkina, Polina A., Tabachkova, Nataliya Yu, Volkova, Tatyana V.

“…•The local structure of ZrO2-Yb2O3-R2O3 (R-Y,Sc) was studied by optical spectroscopy.•The features of oxygen vacancies positions relative of Sc3+, Yb3+, Y3+…”
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Synthetic analogues of memantine as neuroprotective and influenza viral inhibitors: in vitro and physicochemical studies by Tencheva, Aleksandra, Liu, Rui, Volkova, Tatyana V., Chayrov, Radoslav, Mitrev, Yavor, Štícha, Martin, Li, Yuhuan, Jiang, Hailun, Li, Zhuorong, Stankova, Ivanka, Perlovich, German L.

“…Drug compounds including memantine moieties are an important group of biologically active agents for different pathologies, including the Alzheimer’s disease…”
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Polymeric composites of 1,2,4-thiadiazole: solubility, dissolution and permeability assay by Volkova, Tatyana V., Domanina, Ekaterina N., Chislov, Mikhail V., Proshin, Alexey N., Terekhova, Irina V.

“…The derivative of 1,2,4-thiadiazole (TDZ) can be considered as a perspective agent for the Alzheimer’s disease prevention. Due to a highly lipophilic…”
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The effect of different polymers on the solubility, permeability and distribution of poor soluble 1,2,4-thiadiazole derivative by Volkova, Tatyana V., Domanina, Ekaterina N., Kumeev, Roman S., Proshin, Alexey N., Terekhova, Irina V.

“…Solubility and permeability are the main parameters determining the bioavailability of drugs. In this study the increased solubility of novel 1,2,4-thiadiazole…”
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Novel 1,2,4-Thiadiazole Derivatives as Potent Neuroprotectors: Approach to Creation of Bioavailable Drugs by Perlovich, German L, Proshin, Alexey N, Volkova, Tatyana V, Petrova, Ludmila N, Bachurin, Sergey O

“…Novel 1,2,4-thiadiazole derivatives as potent neuroprotectors were synthesized and identified. Their ability to inhibit the glutamate stimulated Ca uptake was…”
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Solubility and distribution of bicycle derivatives of 1,3-selenazine in pharmaceutically relevant media by saturation shake-flask method by Blokhina, Svetlana V., Ol'khovich, Marina V., Sharapova, Angelica V., Volkova, Tatyana V., Proshin, Alexey N., Perlovich, German L.

“…•Solubility of biologically active selenium bicyclic compounds were measured.•Temperature dependence of distribution coefficients in two-phase systems was…”
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