Search Results - "Tatum, Sean M."
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Ceramides and other sphingolipids as drivers of cardiovascular disease
Published in Nature reviews cardiology (01-10-2021)“…Increases in calorie consumption and sedentary lifestyles are fuelling a global pandemic of cardiometabolic diseases, including coronary artery disease,…”
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2
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure
Published in Cell metabolism (02-03-2021)“…The metabolic rewiring of cardiomyocytes is a widely accepted hallmark of heart failure (HF). These metabolic changes include a decrease in mitochondrial…”
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Germline and conditional ghrelin knockout increases islet size
Published in The Journal of clinical investigation (15-12-2023)“…Conflicting studies in recent years report that genetic or pharmacological increases or decreases in ghrelin either increase or have no effect on islet size…”
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4
Ceramides are fuel gauges on the drive to cardiometabolic disease
Published in Physiological reviews (01-07-2024)“…Ceramides are signals of fatty acid excess that accumulate when a cell's energetic needs have been met and its nutrient storage has reached capacity. As these…”
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Skeletal muscle-specific inducible AMPKα1/α2 knockout mice develop muscle weakness, glycogen depletion, and fibrosis that persists during disuse atrophy
Published in American journal of physiology: endocrinology and metabolism (01-01-2024)“…The 5' adenosine monophosphate-activated protein kinase (AMPK) is an important skeletal muscle regulator implicated as a possible therapeutic target to…”
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6
Germline and conditional ghrelin knockout increases islet size
Published in The Journal of clinical investigation (15-12-2023)“…Conflicting studies in recent years report that genetic or pharmacological increases or decreases in ghrelin either increase or have no effect on islet size…”
Get full text
Journal Article