Search Results - "Tatsuya Atsumi"

COVID-19 pandemic in Japan by Amengual, Olga, Atsumi, Tatsuya

“…The disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Coronavirus Disease-2019 (COVID-19), is a global emergency. The first…”
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Enhanced Formation and Disordered Regulation of NETs in Myeloperoxidase-ANCA-Associated Microscopic Polyangiitis by NAKAZAWA, Daigo, SHIDA, Haruki, TOMARU, Utano, YOSHIDA, Masaharu, NISHIO, Saori, ATSUMI, Tatsuya, ISHIZU, Akihiro

“…Microscopic polyangiitis (MPA) is an ANCA-associated vasculitis that affects small vessels, especially renal glomeruli. We recently demonstrated that the…”
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Thrombomodulin as a Physiological Modulator of Intravascular Injury by Watanabe-Kusunoki, Kanako, Nakazawa, Daigo, Ishizu, Akihiro, Atsumi, Tatsuya

“…Thrombomodulin (TM), which is predominantly expressed on the endothelium, plays an important role in maintaining vascular homeostasis by regulating the…”
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Systemic lupus erythematosus: nothing stale her infinite variety by Oku, Kenji, Atsumi, Tatsuya

“…Systemic lupus erythematosus (SLE) is a representative systemic autoimmune disease that has various types of manifestations in multiple organs. Additionally,…”
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Reversible Diffuse Bronchial Wall Thickening by Aso, Kuniyuki, Fujieda, Yuichiro, Atsumi, Tatsuya

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Lipid Droplet Protein PLIN1 Regulates Inflammatory Polarity in Human Macrophages and is Involved in Atherosclerotic Plaque Development by Promoting Stable Lipid Storage by Cho, Kyu Yong, Miyoshi, Hideaki, Nakamura, Akinobu, Greenberg, Andrew S, Atsumi, Tatsuya

“…Aim: Perilipins (PLINs), peripheral lipid droplet (LD) proteins, play important roles in lipid accumulation and maturation in adipocytes. The relationship…”
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Itaconate ameliorates autoimmunity by modulating T cell imbalance via metabolic and epigenetic reprogramming by Aso, Kuniyuki, Kono, Michihito, Kanda, Masatoshi, Kudo, Yuki, Sakiyama, Kodai, Hisada, Ryo, Karino, Kohei, Ueda, Yusho, Nakazawa, Daigo, Fujieda, Yuichiro, Kato, Masaru, Amengual, Olga, Atsumi, Tatsuya

“…Dysregulation of Th17 and Treg cells contributes to the pathophysiology of many autoimmune diseases. Herein, we show that itaconate, an immunomodulatory…”
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Amelioration of fatty liver index in patients with type 2 diabetes on ipragliflozin: an association with glucose-lowering effects by Takase, Takahiro, Nakamura, Akinobu, Miyoshi, Hideaki, Yamamoto, Chiho, Atsumi, Tatsuya

“…In this study, we investigated the ameliorating effects of ipragliflozin on fatty liver in patients with type 2 diabetes. The factors that influenced the…”
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Antiresorptive agents-related osteonecrosis of the jaw (ARONJ) in rheumatoid arthritis by Fujieda, Yuichiro, Atsumi, Tatsuya

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Efficacy of the antiphospholipid score for the diagnosis of antiphospholipid syndrome and its predictive value for thrombotic events by Otomo, Kotaro, Atsumi, Tatsuya, Amengual, Olga, Fujieda, Yuichiro, Kato, Masaru, Oku, Kenji, Horita, Tetsuya, Yasuda, Shinsuke, Koike, Takao

“…Objective To define the antiphospholipid score (aPL‐S) by testing multiple antiphospholipid antibodies (aPL) and to evaluate its efficacy for the diagnosis of…”
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Has lupus anticoagulant testing had its day? by Fujieda, Yuichiro, Atsumi, Tatsuya

“…Antibodies against phosphatidylserine–prothrombin complexes (PS–PT) are one type of antiphospholipid antibody that is responsible for lupus anticoagulant…”
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Long-term efficacy and safety of tocilizumab in refractory Takayasu arteritis: final results of the randomized controlled phase 3 TAKT study by Nakaoka, Yoshikazu, Isobe, Mitsuaki, Tanaka, Yoshiya, Ishii, Tomonori, Ooka, Seido, Niiro, Hiroaki, Tamura, Naoto, Banno, Shogo, Yoshifuji, Hajime, Sakata, Yasushi, Kawakami, Atsushi, Atsumi, Tatsuya, Furuta, Shunsuke, Kohsaka, Hitoshi, Suzuki, Katsuya, Hara, Ryoki, Maejima, Yasuhiro, Tsukamoto, Hiroshi, Takasaki, Yoshinari, Yamashita, Katsuhisa, Okada, Norihiro, Yamakido, Shinji, Takei, Syuji, Yokota, Shumpei, Nishimoto, Norihiro

“…Abstract Objective To investigate the long-term efficacy and safety of the IL-6 receptor antibody tocilizumab in patients with Takayasu arteritis (TAK)…”
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An Antiphospholipid Antibody Profile as a Biomarker for Thrombophilia in Systemic Lupus Erythematosus by Hisada, Ryo, Atsumi, Tatsuya

“…Despite recent advances in treatment and significant improvements in prognosis, thrombosis remains the major cause of death in systemic lupus erythematosus…”
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Positive association between the proinsulin-to-C-peptide ratio and prolonged hyperglycemic time in type 2 diabetes by Miya, Aika, Nakamura, Akinobu, Nomoto, Hiroshi, Kameda, Hiraku, Atsumi, Tatsuya

“…The proinsulin-to-C-peptide (PI:C) ratio is an index applied during the early stage of pancreatic β-cell dysfunction. The aim of this study was to identify the…”
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Antiphospholipid syndrome, "the best prophet of the future" by Amengual, Olga, Atsumi, Tatsuya

“…The antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the occurrence of venous and arterial thromboses, often multiple, and…”
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LAMP3 induces apoptosis and autoantigen release in Sjögren’s syndrome patients by Tanaka, Tsutomu, Warner, Blake M., Odani, Toshio, Ji, Youngmi, Mo, Ying-Qian, Nakamura, Hiroyuki, Jang, Shyh-Ing, Yin, Hongen, Michael, Drew G., Hirata, Noriyuki, Suizu, Futoshi, Ishigaki, Satoko, Oliveira, Fabiola Reis, Motta, Ana Carolina F., Ribeiro-Silva, Alfredo, Rocha, Eduardo M., Atsumi, Tatsuya, Noguchi, Masayuki, Chiorini, John A.

“…Primary Sjögren’s syndrome (pSS) is a complex autoimmune disease characterized by dysfunction of secretory epithelia with only palliative therapy. Patients…”
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16th International congress on antiphospholipid antibodies task force report on antiphospholipid syndrome laboratory diagnostics and trends by Atsumi, Tatsuya, Chighizola, Cecilia B, Fujieda, Yuichiro, Mackie, Ian, Radin, Massimo, Roubey, Robert, Bertolaccini, Maria Laura

“…Classification criteria for antiphospholipid syndrome (APS) require IgG or IgM isotypes of the anticardiolipin (aCL) antibodies, anti-β2 glycoprotein I…”
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Comparison of adding tocilizumab to methotrexate with switching to tocilizumab in patients with rheumatoid arthritis with inadequate response to methotrexate: 52-week results from a prospective, randomised, controlled study (SURPRISE study) by Kaneko, Yuko, Atsumi, Tatsuya, Tanaka, Yoshiya, Inoo, Masayuki, Kobayashi-Haraoka, Hitomi, Amano, Koichi, Miyata, Masayuki, Murakawa, Yohko, Yasuoka, Hidekata, Hirata, Shintaro, Nagasawa, Hayato, Tanaka, Eiichi, Miyasaka, Nobuyuki, Yamanaka, Hisashi, Yamamoto, Kazuhiko, Takeuchi, Tsutomu

“…To compare the efficacy and safety between tocilizumab added to methotrexate and tocilizumab switched from methotrexate in patients with active rheumatoid…”
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Log-linear relationship between endogenous insulin secretion and glycemic variability in patients with type 2 diabetes on continuous glucose monitoring by Miya, Aika, Nakamura, Akinobu, Handa, Takahisa, Nomoto, Hiroshi, Kameda, Hiraku, Cho, Kyu Yong, Nagai, So, Ito, Yoichi M., Miyoshi, Hideaki, Atsumi, Tatsuya

“…The contribution of endogenous insulin secretion to glycemic variability (GV) may differ between patients with impaired insulin secretion and those with…”
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Rheumatology practice in Japan: challenges and opportunities by Oku, Kenji, Atsumi, Tatsuya

“…This article aims to and describes the characteristics of rheumatology practice in Japan, focusing on the medical environment for the treatment of rheumatoid…”
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