Search Results - "Tatsumi, Koichiro"
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Vascular remodeling in pulmonary arterial hypertension: Multiple cancer-like pathways and possible treatment modalities
Published in International journal of cardiology (17-02-2011)“…Abstract Most patients with severe pulmonary arterial hypertension (PAH) demonstrate persistent structural alterations in small pulmonary arterioles at the…”
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Endothelial cells and pulmonary arterial hypertension: apoptosis, proliferation, interaction and transdifferentiation
Published in Respiratory research (13-10-2009)“…Severe pulmonary arterial hypertension, whether idiopathic or secondary, is characterized by structural alterations of microscopically small pulmonary…”
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Vildagliptin ameliorates pulmonary fibrosis in lipopolysaccharide-induced lung injury by inhibiting endothelial-to-mesenchymal transition
Published in Respiratory research (16-10-2017)“…Pulmonary fibrosis is a late manifestation of acute respiratory distress syndrome (ARDS). Sepsis is a major cause of ARDS, and its pathogenesis includes…”
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Reference values for spirometry, including vital capacity, in Japanese adults calculated with the LMS method and compared with previous values
Published in Respiratory investigation (01-07-2014)“…Abstract Background Reference values for lung function tests should be periodically updated because of birth cohort effects and improved technology. This study…”
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Effectiveness and Outcome of Pulmonary Arterial Hypertension-Specific Therapy in Japanese Patients With Pulmonary Arterial Hypertension
Published in Circulation Journal (01-01-2018)“…Background:The trend of the initial treatment strategy for pulmonary arterial hypertension (PAH) has changed from monotherapies to upfront combination…”
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Pathophysiological Roles of Stress-Activated Protein Kinases in Pulmonary Fibrosis
Published in International journal of molecular sciences (03-06-2021)“…Idiopathic pulmonary fibrosis (IPF) is one of the most symptomatic progressive fibrotic lung diseases, in which patients have an extremely poor prognosis…”
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Isolation and characterization of endothelial-to-mesenchymal transition cells in pulmonary arterial hypertension
Published in American journal of physiology. Lung cellular and molecular physiology (01-01-2018)“…Endothelial-to-mesenchymal transition (EndMT) is a process in which endothelial cells lose polarity and cell-to cell contacts, and undergo a dramatic…”
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Clinical characteristics of pulmonary nocardiosis in immunocompetent patients
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01-11-2016)“…Abstract Pulmonary nocardiosis is a rare but potentially serious infection typically in immunosuppressed patients (ISPs). It is also known to occur in…”
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Inhaled GM-CSF for Pulmonary Alveolar Proteinosis
Published in The New England journal of medicine (05-09-2019)“…In patients with autoimmune pulmonary alveolar proteinosis, the use of inhaled recombinant granulocyte–macrophage colony-stimulating factor resulted in a…”
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Selexipag for the treatment of chronic thromboembolic pulmonary hypertension
Published in The European respiratory journal (01-07-2022)“…Background Treatment options for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) remain limited. Selexipag, an oral selective IP prostacyclin…”
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Endobronchial Ultrasonography for Positron Emission Tomography and Computed Tomography–Negative Lymph Node Staging in Non-Small Cell Lung Cancer
Published in The Annals of thoracic surgery (01-11-2014)“…Background Integrated positron emission tomography (PET) with computed tomography (CT) is a useful modality to investigate lymph node metastases for non-small…”
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Different Transcriptome Features of Peripheral Blood Mononuclear Cells in Non-Emphysematous Chronic Obstructive Pulmonary Disease
Published in International journal of molecular sciences (20-12-2023)“…Non-emphysematous chronic obstructive pulmonary disease (COPD), which is defined based on chest computed tomography findings, presented different transcriptome…”
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Effects of Anti-Fibrotic Drugs on Transcriptome of Peripheral Blood Mononuclear Cells in Idiopathic Pulmonary Fibrosis
Published in International journal of molecular sciences (01-04-2024)“…Two anti-fibrotic drugs, pirfenidone (PFD) and nintedanib (NTD), are currently used to treat idiopathic pulmonary fibrosis (IPF). Peripheral blood mononuclear…”
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Neutrophil-to-lymphocyte ratio is a prognostic factor reflecting immune condition of tumor microenvironment in squamous cell lung cancer
Published in Scientific reports (03-01-2024)“…Inflammatory factors in the peripheral blood, such as the C-reactive protein level and neutrophil-to-lymphocyte ratio (NLR), are prognostic markers in multiple…”
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Risk factors for skeletal-related events in non-small cell lung cancer patients treated with bone-modifying agents
Published in Supportive care in cancer (01-07-2021)“…Purpose The risk factors for skeletal-related events (SREs) among non-small cell lung cancer (NSCLC) patients during treatment with bone-modifying agents…”
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Long-Term Outcome of Chronic Thromboembolic Pulmonary Hypertension at a Single Japanese Pulmonary Endarterectomy Center
Published in Circulation Journal (2018)“…Background:Several new treatments for chronic thromboembolic pulmonary hypertension (CTEPH) have appeared in recent years, which have led to changes in the…”
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Recent progress in the diagnosis and management of chronic thromboembolic pulmonary hypertension
Published in Respiratory investigation (01-09-2013)“…Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a form of pulmonary hypertension caused by non-resolving thromboembolisms of the pulmonary…”
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Long-term outcome after pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension
Published in The Journal of thoracic and cardiovascular surgery (01-08-2012)“…Objectives Pulmonary endarterectomy is the treatment of choice for chronic thromboembolic pulmonary hypertension. Although several reports demonstrated…”
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Endothelial cell-related autophagic pathways in Sugen/hypoxia-exposed pulmonary arterial hypertensive rats
Published in American journal of physiology. Lung cellular and molecular physiology (01-11-2017)“…Pulmonary arterial hypertension (PAH) is characterized by progressive obstructive remodeling of pulmonary arteries. However, no reports have described the…”
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