Search Results - "Tatosian, DA"

Validation of a microdose probe drug cocktail for clinical drug interaction assessments for drug transporters and CYP3A by Prueksaritanont, T, Tatosian, DA, Chu, X, Railkar, R, Evers, R, Chavez‐Eng, C, Lutz, R, Zeng, W, Yabut, J, Chan, GH, Cai, X, Latham, AH, Hehman, J, Stypinski, D, Brejda, J, Zhou, C, Thornton, B, Bateman, KP, Fraser, I, Stoch, SA

“…A microdose cocktail containing midazolam, dabigatran etexilate, pitavastatin, rosuvastatin, and atorvastatin has been established to allow simultaneous…”
Get full text

Leveraging a Clinical Phase Ib Proof‐of‐Concept Study for the GPR40 Agonist MK‐8666 in Patients With Type 2 Diabetes for Model‐Informed Phase II Dose Selection by Krug, AW, Vaddady, P, Railkar, RA, Musser, BJ, Cote, J, Ederveen, AGH, Krefetz, DG, DeNoia, E, Free, AL, Morrow, L, Chakravarthy, MV, Kauh, E, Tatosian, DA, Kothare, PA

“…GPR40 mediates free fatty acid–induced insulin secretion in beta cells. We investigated the safety, pharmacokinetics, and glucose response of MK‐8666, a…”
Get full text

Portable in situ fluorescence cytometry of microscale cell-based assays by Tatosian, Daniel A, Shuler, Michael L, Kim, Donghyun

“…A portable fluorescence cytometric system has been developed for characterizing chemical concentration and cellular status in microscale cell culture analog…”
Get more information