Search Results - "Tatematsu, Bruna K"
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Vγ1 and Vγ4 gamma-delta T cells play opposing roles in the immunopathology of traumatic brain injury in males
Published in Nature communications (18-07-2023)“…Traumatic brain injury (TBI) is a leading cause of morbidity and mortality. The innate and adaptive immune responses play an important role in the pathogenesis…”
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Gamma-delta T cells modulate the microbiota and fecal micro-RNAs to maintain mucosal tolerance
Published in Microbiome (23-02-2023)“…Gamma-delta (γδ) T cells are a major cell population in the intestinal mucosa and are key mediators of mucosal tolerance and microbiota composition. Little is…”
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Nasal administration of anti-CD3 monoclonal antibody ameliorates disease in a mouse model of Alzheimer's disease
Published in Proceedings of the National Academy of Sciences - PNAS (12-09-2023)“…Emerging evidence suggests that dysregulation of neuroinflammation, particularly that orchestrated by microglia, plays a significant role in the pathogenesis…”
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γδ T Cell-Secreted XCL1 Mediates Anti-CD3-Induced Oral Tolerance
Published in The Journal of immunology (1950) (15-11-2019)“…Oral tolerance is defined as the specific suppression of cellular and/or humoral immune responses to an Ag by prior administration of the Ag through the oral…”
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Gamma-delta T cells suppress microbial metabolites that activate striatal neurons and induce repetitive/compulsive behavior in mice
Published in Brain, behavior, and immunity (01-03-2024)“…•γδ T cells regulate the gut microbiota.•In the absence of γδ T cells, mice develop a microbial dysbiosis with the growth of microbes involved in the…”
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