Search Results - "Tatebayashi, Tomoko"
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A study of the intestinal absorption of an ester-type prodrug, ME3229, in rats: active efflux transport as a cause of poor bioavailability of the active drug
Published in The Journal of pharmacology and experimental therapeutics (01-08-2000)“…The intestinal absorption of a prodrug is affected by a number of factors, such as its membrane permeability, stability in the gut lumen, and conversion to the…”
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Chronic treatment with fluvoxamine desensitizes 5-HT2C receptor-mediated hypolocomotion in rats
Published in Pharmacology, biochemistry and behavior (01-08-2004)“…The effectiveness of fluvoxamine, a selective serotonin re-uptake inhibitor (SSRI), in the treatment of anxiety disorders, such as obsessive-compulsive, panic…”
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Physiological models are good tools to predict rat bioavailability of EF5154 prodrugs from in vitro intestinal parameters
Published in Journal of pharmaceutical sciences (01-04-2009)“…There are only a few reports on the methods that predict in vivo bioavailability from in vitro intestinal parameters. In the present study, we constructed…”
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Chronic treatment with fluvoxamine desensitizes 5-HT 2C receptor-mediated hypolocomotion in rats
Published in Pharmacology, biochemistry and behavior (2004)“…The effectiveness of fluvoxamine, a selective serotonin re-uptake inhibitor (SSRI), in the treatment of anxiety disorders, such as obsessive-compulsive, panic…”
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Mutagenicity study of the new cephalosporin antibiotic cefditoren pivoxil
Published in Arzneimittel-Forschung (01-08-1996)“…The mutagenicity of a cephalosporin antibiotic, (-)-(6R,7R)-2,2-dimethylpropionyloxymethyl 7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-[(Z)-2-…”
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