Search Results - "Tate, Michelle D"

MicroRNA as Type I Interferon-Regulated Transcripts and Modulators of the Innate Immune Response by Forster, Samuel C, Tate, Michelle D, Hertzog, Paul J

“…Type I interferons (IFNs) are an important family of cytokines that regulate innate and adaptive immune responses to pathogens, in cancer and inflammatory…”
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Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease by McAuley, Julie L, Tate, Michelle D, MacKenzie-Kludas, Charley J, Pinar, Anita, Zeng, Weiguang, Stutz, Andrea, Latz, Eicke, Brown, Lorena E, Mansell, Ashley

“…The ability for a host to recognize infection is critical for virus clearance and often begins with induction of inflammation. The PB1-F2 of pathogenic…”
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Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation by Lang, Tali, Lee, Jacinta P. W., Elgass, Kirstin, Pinar, Anita A., Tate, Michelle D., Aitken, Elizabeth H., Fan, Huapeng, Creed, Sarah J., Deen, Nadia S., Traore, Daouda A. K., Mueller, Ivo, Stanisic, Danielle, Baiwog, Francesca S., Skene, Colin, Wilce, Matthew C. J., Mansell, Ashley, Morand, Eric F., Harris, James

“…Macrophage migration inhibitory factor (MIF) exerts multiple effects on immune cells, as well as having functions outside the immune system. MIF can promote…”
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Taking AIM at Influenza: The Role of the AIM2 Inflammasome by Xu, Dianne W, Tate, Michelle D

“…Influenza A viruses (IAV) are dynamic and highly mutable respiratory pathogens that present persistent public health challenges. Inflammasomes, as components…”
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Die Another Way: Interplay between Influenza A Virus, Inflammation and Cell Death by Laghlali, Gabriel, Lawlor, Kate E, Tate, Michelle D

“…Influenza A virus (IAV) is a major concern to human health due to the ongoing global threat of a pandemic. Inflammatory and cell death signalling pathways play…”
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Repurposing drugs targeting the P2X7 receptor to limit hyperinflammation and disease during influenza virus infection by Rosli, Sarah, Kirby, Francis J., Lawlor, Kate E., Rainczuk, Kate, Drummond, Grant R., Mansell, Ashley, Tate, Michelle D.

“…Background and Purpose Severe influenza A virus (IAV) infections are associated with damaging hyperinflammation that can be fatal. There is an urgent need to…”
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The role of neutrophils during mild and severe influenza virus infections of mice by Tate, Michelle D, Ioannidis, Lisa J, Croker, Ben, Brown, Lorena E, Brooks, Andrew G, Reading, Patrick C

“…Neutrophils have been implicated in both protective and pathological responses following influenza virus infections. We have used mAb 1A8 (anti-Ly6G) to…”
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Playing hide and seek: how glycosylation of the influenza virus hemagglutinin can modulate the immune response to infection by Tate, Michelle D, Job, Emma R, Deng, Yi-Mo, Gunalan, Vithiagaran, Maurer-Stroh, Sebastian, Reading, Patrick C

“…Seasonal influenza A viruses (IAV) originate from pandemic IAV and have undergone changes in antigenic structure, including addition of glycans to the…”
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Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection by Tate, Michelle D, Deng, Yi-Mo, Jones, Jessica E, Anderson, Gary P, Brooks, Andrew G, Reading, Patrick C

“…The clinical response to influenza infection ranges from mild disease to severe pneumonia and it remains unclear whether the inflammatory response to infection…”
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Critical Role of Airway Macrophages in Modulating Disease Severity during Influenza Virus Infection of Mice by Tate, Michelle D, Pickett, Danielle L, van Rooijen, Nico, Brooks, Andrew G, Reading, Patrick C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Aggregated Hendra virus C-protein activates the NLRP3 inflammasome to induce inflammation by Barry, Kristian, Harpur, Christopher, Lam, Maggie, Tate, Michelle D, Mansell, Ashley

“…Abstract Background Hendra virus is an emerging virus with a geographically broad host reservoir. In humans, Hendra virus causes excessive inflammatory disease…”
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Gasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection by Rosli, Sarah, Harpur, Christopher M., Lam, Maggie, West, Alison C., Hodges, Christopher, Mansell, Ashley, Lawlor, Kate E., Tate, Michelle D.

“…Excessive inflammation and tissue damage during severe influenza A virus (IAV) infection can lead to the development of fatal pulmonary disease. Pyroptosis is…”
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Specific sites of N-linked glycosylation on the hemagglutinin of H1N1 subtype influenza A virus determine sensitivity to inhibitors of the innate immune system and virulence in mice by Tate, Michelle D, Brooks, Andrew G, Reading, Patrick C

“…Oligosaccharides on the hemagglutinin (HA) and neuraminidase of influenza A virus (IAV) are a target for recognition by lectins of the innate immune system,…”
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ADAM17 selectively activates the IL‐6 trans‐signaling/ERK MAPK axis in KRAS‐addicted lung cancer by Saad, Mohamed I, Alhayyani, Sultan, McLeod, Louise, Yu, Liang, Alanazi, Mohammad, Deswaerte, Virginie, Tang, Ke, Jarde, Thierry, Smith, Julian A, Prodanovic, Zdenka, Tate, Michelle D, Balic, Jesse J, Watkins, D Neil, Cain, Jason E, Bozinovski, Steven, Algar, Elizabeth, Kohmoto, Tomohiro, Ebi, Hiromichi, Ferlin, Walter, Garbers, Christoph, Ruwanpura, Saleela, Sagi, Irit, Rose‐John, Stefan, Jenkins, Brendan J

“…Oncogenic KRAS mutations are major drivers of lung adenocarcinoma (LAC), yet the direct therapeutic targeting of KRAS has been problematic. Here, we reveal an…”
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Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection by Coldbeck-Shackley, Rosa C, Romeo, Ornella, Rosli, Sarah, Gearing, Linden J, Gould, Jodee A, Lim, San S, Van der Hoek, Kylie H, Eyre, Nicholas S, Shue, Byron, Robertson, Sarah A, Best, Sonja M, Tate, Michelle D, Hertzog, Paul J, Beard, Michael R

“…The immunological surveillance factors controlling vulnerability of the female reproductive tract (FRT) to sexually transmitted viral infections are not well…”
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Flu on the Brain: Identification of Highly Pathogenic Influenza in the Brains of Wild Carnivores in The Netherlands by Barry, Kristian T, Tate, Michelle D

“…Highly pathogenic avian influenza (HPAI) viruses circulate in wild birds and can infect domestic poultry [...]…”
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N-Linked Glycosylation Facilitates Sialic Acid-Independent Attachment and Entry of Influenza A Viruses into Cells Expressing DC-SIGN or L-SIGN by LONDRIGAN, Sarah L, TURVILLE, Stuart G, TATE, Michelle D, DENG, Yi-Mo, BROOKS, Andrew G, READING, Patrick C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema by Ruwanpura, Saleela M, McLeod, Louise, Dousha, Lovisa F, Seow, Huei J, Alhayyani, Sultan, Tate, Michelle D, Deswaerte, Virginie, Brooks, Gavin D, Bozinovski, Steven, MacDonald, Martin, Garbers, Christoph, King, Paul T, Bardin, Philip G, Vlahos, Ross, Rose-John, Stefan, Anderson, Gary P, Jenkins, Brendan J

“…The potent immunomodulatory cytokine IL-6 is consistently up-regulated in human lungs with emphysema and in mouse emphysema models; however, the mechanisms by…”
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Too young to die? How aging affects cellular innate immune responses to influenza virus and disease severity by Harpur, Christopher M., Le Page, Mélanie A., Tate, Michelle D.

“…Influenza is a respiratory viral infection that causes significant morbidity and mortality worldwide. The innate immune cell response elicited during influenza…”
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Cell-surface receptors on macrophages and dendritic cells for attachment and entry of influenza virus by Londrigan, Sarah L., Tate, Michelle D., Brooks, Andrew G., Reading, Patrick C.

“…Review of interactions between influenza A virus and C‐type lectin receptors on macrophages and dendritic cells that may result in virus entry and infection…”
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