Search Results - "Tata, Prasanthi"

Predictive nonlinear modeling of malignant myelopoiesis and tyrosine kinase inhibitor therapy by Rodriguez, Jonathan, Iniguez, Abdon, Jena, Nilamani, Tata, Prasanthi, Liu, Zhong-Ying, Lander, Arthur D, Lowengrub, John, Van Etten, Richard A

“…Chronic myeloid leukemia (CML) is a blood cancer characterized by dysregulated production of maturing myeloid cells driven by the product of the Philadelphia…”
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The impact of Rhodiola rosea on biomarkers of diabetes, inflammation, and microbiota in a leptin receptor-knockout mouse model by Jafari, Mahtab, Juanson Arabit, Jasmin Grace, Courville, Robert, Kiani, Dara, Chaston, John M., Nguyen, Cindy Duy, Jena, Nilamani, Liu, Zhong-Ying, Tata, Prasanthi, Van Etten, Richard A.

“…Type 2 diabetes is the most prevalent endocrine disease in the world, and recently the gut microbiota have become a potential target for its management. Recent…”
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Increased BCR responsiveness in B cells from patients with chronic GVHD by Allen, Jessica L., Tata, Prasanthi V., Fore, Matthew S., Wooten, Jenna, Rudra, Sharmistha, Deal, Allison M., Sharf, Andrew, Hoffert, Todd, Roehrs, Philip A., Shea, Thomas C., Serody, Jonathan S., Richards, Kristy L., Jagasia, Madan, Lee, Stephanie J., Rizzieri, David, Horwitz, Mitchell E., Chao, Nelson J., Sarantopoulos, Stefanie

“…Although B cells have emerged as important contributors to chronic graft-versus-host-disease (cGVHD) pathogenesis, the mechanisms responsible for their…”
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An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD by Poe, Jonathan C., Jia, Wei, Su, Hsuan, Anand, Sarah, Rose, Jeremy J., Tata, Prasanthi V., Suthers, Amy N., Jones, Corbin D., Kuan, Pei Fen, Vincent, Benjamin G., Serody, Jonathan S., Horwitz, Mitchell E., Ho, Vincent T., Pavletic, Steven Z., Hakim, Frances T., Owzar, Kouros, Zhang, Dadong, Blazar, Bruce R., Siebel, Christian W., Chao, Nelson J., Maillard, Ivan, Sarantopoulos, Stefanie

“…B-cell receptor (BCR)-activated B cells contribute to pathogenesis in chronic graft-versus-host disease (cGVHD), a condition manifested by both B-cell…”
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Optimal experimental design for mathematical models of haematopoiesis by Lomeli, Luis Martinez, Iniguez, Abdon, Tata, Prasanthi, Jena, Nilamani, Liu, Zhong-Ying, Van Etten, Richard, Lander, Arthur D, Shahbaba, Babak, Lowengrub, John S, Minin, Vladimir N

“…The haematopoietic system has a highly regulated and complex structure in which cells are organized to successfully create and maintain new blood cells. It is…”
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Overexpression of Calreticulin Impairs Self-Renewal Capacity of Hematopoietic Stem Cells by Brooks, Stefan, Morse, Sarah, Craver, Brianna, Lai, Hew Yeng, Nguyen, Thanh Kim, Kim, Daniel, Fleischman, Angela G., Tata, Prasanthi, Jena, Nilamani, Liu, Zhong-Ying, Van Etten, Richard A.

“…Mutations in JAK2, c-MPL and CALR have all been identified as drivers of MPN pathogenesis. JAK2 and c-MPL are critical for hematopoietic stem cell self-renewal…”
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The MEK/ERK Inhibitor Trametinib Reduces Fibrosis in a Transduction-Transplantation Model of Mutated Calreticulin by Nguyen, Thanh Kim, Tata, Prasanthi, Brooks, Stefan, Jena, Nilamani, Morse, Sarah J, Liu, Zhong-ying, Lai, Hew Yeng, Rezk, Sherif, Van Etten, Richard A., Fleischman, Angela G

“…▪ Insertion or deletion mutations in calreticulin (CALR) are present in the majority of JAK2V617F-negative MPN patients. We utilized a murine retroviral…”
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High-Throughput Immunoglobulin Heavy Chain Variable Region Repertoire Analysis Of CD27+ B Cell Subsets From Patients With Chronic Gvhd by Tata, Prasanthi V., Vincent, Benjamin G., Kuan, Pei-Fen, Jones, Corbin, Serody, Jonathan, Sarantopoulos, Stefanie

“…Patients with chronic graft versus host disease (cGVHD) have persistently altered B cell homeostasis and loss of B cell tolerance, even years after allogeneic…”
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Abstract 4202: Targeting focal adhesion kinase is a novel approach to therapy of high-risk, Ikaros-mutant acute B-cell lymphoblastic leukemia by Jena, Nilamani, Joshi, Ila, Yoshida, Toshimi, Zhang, Zhihong, Liu, Zhong-Ying, Tata, Prasanthi, Shapiro, Irina M., Pachter, Jonathan A., Weaver, David T., Georgopoulos, Katia, Van Etten, Richard A.

“…Deletions and dominant-negative mutations in IKZF1, the gene encoding Ikaros transcription factor, are found in ∼85% of Ph+ B-ALL and in some cases of Ph−…”
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Central role for ikaros in pre-B cell differentiation and pathogenesis of high-risk B-cell acute lymphoblastic leukemia by Van Etten, Richard, Hu, Yeguang, Zhang, Zihong, Yoshida, Toshimi, Jena, Nilamani, Kashiwagi, Mariko, Joshi, Ila, El-Bardeesy, Nabeel, Somasundaram, Rajesh, Sigvardsson, Mikael, Liu, Zhong-Ying, Tata, Prasanthi, Korber, Shane, Raufi, Alex, Krause, Daniela, Paietta, Elisabeth, Georgopoulos, Katia

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BCR Hyper-Responsiveness In B Cells From Patients With Chronic Gvhd Is Blocked With The Syk Inhibitor R406 by Allen, Jessica L., Tata, Prasanthi V., Wooten, Jenna, Fore, Matthew S., Deal, Allison M., Sharf, Andrew, Hoffert, Todd, Roehrs, Philip A., Armistead, Paul M., Coghill, James, Wood, William A., Shea, Thomas C., Serody, Jonathan, Richards, Kristy L., Jagasia, Madan, Lee, Stephanie J., Rowe, Krista, Rizzieri, David, Horwitz, Mitchell E., Chao, Nelson J., Sarantopoulos, Stefanie

“…Our previous findings indicate that the excess BAFF present in patients with chronic GVHD (cGVHD) induces increased metabolic activity and B-cell survival ex…”
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Evaluation of MUC4 glycoprotein as a potential target for immunoliposomes in the treatment of pancreatic adenocarcinoma by Tata, Prasanthi

“…The purpose of this study is to understand the extent to which MUC4 (mucin) can be used to improve targeted delivery to pancreatic tumors and specifically…”
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