Search Results - "Tat, Vivian"

Characterization of Unique Pathological Features of COVID-Associated Coagulopathy: Studies with AC70 hACE2 Transgenic Mice Highly Permissive to SARS-CoV-2 Infection by Drelich, Aleksandra K, Rayavara, Kempaiah, Hsu, Jason, Saenkham-Huntsinger, Panatda, Judy, Barbara M, Tat, Vivian, Ksiazek, Thomas G, Peng, Bi-Hung, Tseng, Chien-Te K

“…COVID-associated coagulopathy seemly plays a key role in post-acute sequelae of SARS- CoV-2 infection. However, the underlying pathophysiological mechanisms…”
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A Bacteriophage-Based, Highly Efficacious, Needle- and Adjuvant-Free, Mucosal COVID-19 Vaccine by Zhu, Jingen, Jain, Swati, Sha, Jian, Batra, Himanshu, Ananthaswamy, Neeti, Kilgore, Paul B, Hendrix, Emily K, Hosakote, Yashoda M, Wu, Xiaorong, Olano, Juan P, Kayode, Adeyemi, Galindo, Cristi L, Banga, Simran, Drelich, Aleksandra, Tat, Vivian, Tseng, Chien-Te K, Chopra, Ashok K, Rao, Venigalla B

“…The U.S. Food and Drug Administration-authorized mRNA- and adenovirus-based SARS-CoV-2 vaccines are intramuscularly injected in two doses and effective in…”
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Evaluation of Type I Interferon Treatment in Hospitalized COVID-19 Patients: A Retrospective Cohort Study by Tat, Vivian Y, Huang, Pinghan, Khanipov, Kamil, Tat, Nathan Y, Tseng, Chien-Te Kent, Golovko, George

“…Coronavirus disease 2019 (COVID-19) continues to cause morbidity and mortality worldwide; therefore, effective treatments remain crucial to controlling it. As…”
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A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta by Carter, Brandon, Huang, Pinghan, Liu, Ge, Liang, Yuejin, Lin, Paulo J C, Peng, Bi-Hung, McKay, Lindsay G A, Dimitrakakis, Alexander, Hsu, Jason, Tat, Vivian, Saenkham-Huntsinger, Panatda, Chen, Jinjin, Kaseke, Clarety, Gaiha, Gaurav D, Xu, Qiaobing, Griffiths, Anthony, Tam, Ying K, Tseng, Chien-Te K, Gifford, David K

“…Licensed COVID-19 vaccines ameliorate viral infection by inducing production of neutralizing antibodies that bind the SARS-CoV-2 Spike protein and inhibit…”
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Self-Masked Aldehyde Inhibitors of Human Cathepsin L Are Potent Anti-CoV-2 Agents by Zhu, Jiyun, Li, Linfeng, Drelich, Aleksandra, Chenna, Bala C., Mellott, Drake M., Taylor, Zane W., Tat, Vivian, Garcia, Christopher Z., Katzfuss, Ardala, Tseng, Chien-Te K., Meek, Thomas D.

“…Cysteine proteases comprise an important class of drug targets, especially for infectious diseases such as Chagas disease (cruzain) and COVID-19 (3CL protease,…”
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Endogenous Type I interferon signaling plays a pivotal role in restricted SARS-CoV-2 infection in human ACE2 transgenic mice by Kempaiah, Kempaiah Rayavara, Drelich, Aleksandra, Hsu, Jason C, Tat, Vivian, Tseng, Chien-Te K

“…Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become pandemic, resulting in severe…”
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Induction of multivalent and balanced T cell responses by modular nanoshell vaccine technology by Huang, Pinghan, Tsai, Hsiao-Han, Tat, Vivian, Hsu, Jason C, Aleksandra, Drelich, Chen, Hui-Wen, Hu, Che-Ming Jack, Tseng, Chien-Te

“…Abstract After the outbreak of COVID-19, cellular immunity has been shown to provide protection especially in breakthrough infection and B cell-deficient…”
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Protective Efficacy of Novel Engineered Human ACE2-Fc Fusion Protein Against Pan-SARS-CoV‑2 Infection In Vitro and in Vivo by Yu, Bo, Drelich, Aleksandra, Hsu, Jason, Tat, Vivian, Peng, Bi-Hung, Wei, Qisheng, Wang, Jianming, Wang, Hong, Wages, John, Mendelsohn, Andrew R., Larrick, James W., Tseng, Chien-Te

“…Enduring occurrence of severe COVID-19 for unvaccinated, aged, or immunocompromised individuals remains an urgent need. Soluble human angiotensin-converting…”
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Efficacy and self-similarity of SARS-CoV-2 thermal decontamination by Yap, Te Faye, Hsu, Jason C., Liu, Zhen, Rayavara, Kempaiah, Tat, Vivian, Tseng, Chien-Te K., Preston, Daniel J.

“…Dry heat decontamination has been shown to effectively inactivate viruses without compromising the integrity of delicate personal protective equipment (PPE),…”
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A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV‑2 Infection of Human and Monkey Cells by Mellott, Drake M, Tseng, Chien-Te, Drelich, Aleksandra, Fajtová, Pavla, Chenna, Bala C, Kostomiris, Demetrios H, Hsu, Jason, Zhu, Jiyun, Taylor, Zane W, Kocurek, Klaudia I, Tat, Vivian, Katzfuss, Ardala, Li, Linfeng, Giardini, Miriam A, Skinner, Danielle, Hirata, Ken, Yoon, Michael C, Beck, Sungjun, Carlin, Aaron F, Clark, Alex E, Beretta, Laura, Maneval, Daniel, Hook, Vivian, Frueh, Felix, Hurst, Brett L, Wang, Hong, Raushel, Frank M, O’Donoghue, Anthony J, de Siqueira-Neto, Jair Lage, Meek, Thomas D, McKerrow, James H

“…Host-cell cysteine proteases play an essential role in the processing of the viral spike protein of SARS coronaviruses. K777, an irreversible, covalent…”
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An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations by Westberg, Michael, Su, Yichi, Zou, Xinzhi, Huang, Pinghan, Rustagi, Arjun, Garhyan, Jaishree, Patel, Puja Bhavesh, Fernandez, Daniel, Wu, Yan, Hao, Chenzhou, Lo, Chieh-Wen, Karim, Marwah, Ning, Lin, Beck, Aimee, Saenkham-Huntsinger, Panatda, Tat, Vivian, Drelich, Aleksandra, Peng, Bi-Hung, Einav, Shirit, Tseng, Chien-Te K, Blish, Catherine, Lin, Michael Z

“…Inhibitors of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (M ) such as nirmatrelvir (NTV) and ensitrelvir (ETV) have proven…”
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Generation of a humanized mAce2 and a conditional hACE2 mouse models permissive to SARS-COV-2 infection by Song, I-Wen, Washington, Megan, Leynes, Carolina, Hsu, Jason, Rayavara, Kempaiah, Bae, Yangjin, Haelterman, Nele, Chen, Yuqing, Jiang, Ming-Ming, Drelich, Aleksandra, Tat, Vivian, Lanza, Denise G., Lorenzo, Isabel, Heaney, Jason D., Tseng, Chien-Te Kent, Lee, Brendan, Marom, Ronit

“…The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) remains a public health concern and a subject of active research effort. Development of…”
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Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 by Doxey, Matthew C, Burkart, Katrin, Bryazka, Dana, Dominguez, Regina-Mae Villanueva, Abdoli, Amir, Aboagye, Richard Gyan, Abu-Zaid, Ahmed, Ahmadi, Sepideh, Alhassan, Robert Kaba, Aljunid, Syed Mohamed, Almustanyir, Sami, Alvis-Guzman, Nelson, Areda, Demelash, Arulappan, Judie, Aujayeb, Avinash, Ayana, Tegegn Mulatu, Azadnajafabad, Sina, Azangou-Khyavy, Mohammadreza, Azari Jafari, Amirhossein, Barone-Adesi, Francesco, Batiha, Abdul-Monim Mohammad, Chattu, Vijay Kumar, Ching, Patrick R, Christopher, Devasahayam J, Cobb, Natalie L, Dandona, Rakhi, Dereje, Diriba, Digesa, Lankamo Ena, Dorostkar, Fariba, Ekholuenetale, Michael, El Sayed Zaki, Maysaa, Fagbamigbe, Adeniyi Francis, Faraj, Anwar, Gaidhane, Abhay Motiramji, Garg, Tushar, Gessner, Bradford D, Getachew, Melaku, Gupta, Veer Bala, Harorani, Mehdi, Hasani, Hamidreza, Hosseini, Mohammad-Salar, Hostiuc, Mihaela, Javanmardi, Fatemeh, Jayarajah, Umesh, Joseph, Nitin, Joukar, Farahnaz, Karaye, Ibraheem M, Katoto, Patrick DMC, Khajuria, Himanshu, Khosravifar, Mina, Kim, Min Seo, Kisa, Sezer, Lee, Sang-woong, Lotfi, Mojgan, Mahmoudi, Razzagh, Mir, Shabir Ahmad, Mirmoeeni, Seyyedmohammadsadeq, Misganaw, Abay Sisay, Moka, Nagabhishek, Momtazmanesh, Sara, Najafi, Houshang, Natto, Zuhair S, Odukoya, Oluwakemi Ololade, Padubidri, Jagadish Rao, Park, Eun-Cheol, Petcu, Ionela-Roxana, Pourtaheri, Naeimeh, Rabiee, Mohammad, Rabiee, Navid, Rahman, Md Obaidur, Rahman, Mosiur, Rahman, Muhammad Aziz, Redwan, Elrashdy Moustafa Mohamed, Rezaeian, Mohsen, Rogowski, Emma L B, Saddik, Basema, Sahebazzamani, Maryam, Sathian, Brijesh, Seylani, Allen, Sharhani, Asaad, Shiferaw, Damtew Solomon, Simpson, Colin R, Singh, Jasvinder A, Skryabina, Anna Aleksandrovna, Soltani-Zangbar, Mohammad Sadegh, Sreeramareddy, Chandrashekhar T, Suleman, Muhammad, Tahamtan, Alireza, Tandukar, Sarmila, Tat, Vivian Y, Temsah, Mohamad-Hani, Thapar, Rekha, Tovani-Palone, Marcos Roberto, Upadhyay, Era, Vardavas, Constantine, Waheed, Yasir, Zarrintan, Armin, Zeng, Wu, Zhang, Mengxi, Zumla, Alimuddin

“…The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as…”
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Global investments in pandemic preparedness and COVID-19: development assistance and domestic spending on health between 1990 and 2026 by Cogswell, Ian E, Pedroza, Paola, Solorio, Juan, Stutzman, Hayley, Wang, Yifeng, Abedi, Aidin, Abolhassani, Hassan, Abrigo, Michael R M, Adem, Mohammed Hussien, Alhassan, Robert Kaba, Al-Raddadi, Rajaa M, Alvis-Zakzuk, Nelson J, Ameyaw, Edward Kwabena, Aqeel, Muhammad, Arabloo, Jalal, Arab-Zozani, Morteza, Aravkin, Aleksandr Y, Barrow, Amadou, Batiha, Abdul-Monim Mohammad, Berezvai, Zombor, Bodolica, Virginia, Charan, Jaykaran, Debela, Sisay Abebe, Denova-Gutiérrez, Edgar, Dharmaratne, Samath Dhamminda, Diao, Nancy, Doan, Linh Phuong, dos Santos, Wendel Mombaque, Eini, Ebrahim, El Sayed Zaki, Maysaa, Enyew, Daniel Berhanie, Faraon, Emerito Jose A, Fekadu, Ginenus, Fowobaje, Kayode Raphael, Fullman, Nancy, Gamkrelidze, Amiran, Garcia-Gordillo, M A, Ghafourifard, Mansour, Gupta, Bhawna, Heyi, Demisu Zenbaba, Hiraike, Yuta, Hosseinzadeh, Mehdi, Hostiuc, Sorin, Jemere, Digisie Mequanint, Jozwiak, Jacek Jerzy, Kadashetti, Vidya, Kadir, Dler Hussein, Kandel, Himal, Karanth, Shama D, Keikavoosi-Arani, Leila, Khajuria, Himanshu, Kim, Hanna, Kim, Jihee, Kisa, Adnan, Kompani, Farzad, Lamnisos, Demetris, Machado, Vanessa Sintra Machado, Magdy Abd El Razek, Mohammed, Mahmoudi, Razzagh, Masoud, Ali, Maude, Richard James, Mechili, Enkeleint A, Meretoja, Atte, Mesregah, Mohamed Kamal, Mirza, Moonis, Moccia, Marcello, Moghadasi, Javad, Mohammadi, Mokhtar, Mohammed, Shafiu, Mohseni, Mohammad, Mokdad, Ali H, Mossialos, Elias, Mpundu-Kaambwa, Christine, Naqvi, Atta Abbas, Nzoputam, Chimezie Igwegbe, Oancea, Bogdan, Palicz, Tamás, Palladino, Raffaele, Patel, Jay, Paun, Mihaela, Perna, Simone, Prada, Sergio I, Ranabhat, Chhabi Lal, Rashidi, Mohammad-Mahdi, Reiner, Robert C, Rodriguez, Jefferson Antonio Buendia, Salari, Hedayat, Sanmarchi, Francesco, Schwendicke, Falk, Sepanlou, Sadaf G, Seylani, Allen, Sheikh, Aziz, Singh, Kuldeep, Song, Suhang, Tichopad, Ales, Vasic, Milena, Wang, Cong, Wickramasinghe, Nuwan Darshana, Zaman, Burhan Abdullah, Hay, Simon I

“…The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led…”
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