Search Results - "Tasuku Nakabori"

Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice by Tanaka, Satoshi, Hikita, Hayato, Tatsumi, Tomohide, Sakamori, Ryotaro, Nozaki, Yasutoshi, Sakane, Sadatsugu, Shiode, Yuto, Nakabori, Tasuku, Saito, Yoshinobu, Hiramatsu, Naoki, Tabata, Keisuke, Kawabata, Tsuyoshi, Hamasaki, Maho, Eguchi, Hidetoshi, Nagano, Hiroaki, Yoshimori, Tamotsu, Takehara, Tetsuo

“…Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease worldwide. It encompasses a spectrum ranging from simple steatosis to fatty liver…”
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Hepatitis C virus infection suppresses hepatitis B virus replication via the RIG-I-like helicase pathway by Murai, Kazuhiro, Hikita, Hayato, Kai, Yugo, Kondo, Yasuteru, Fukuoka, Makoto, Fukutomi, Keisuke, Doi, Akira, Yamai, Takuo, Nakabori, Tasuku, Fukuda, Ryo, Takahashi, Takeshi, Miyakawa, Kei, Suemizu, Hiroshi, Ryo, Akihide, Yamada, Ryoko, Kodama, Takahiro, Sakamori, Ryotaro, Tatsumi, Tomohide, Takehara, Tetsuo

“…Mechanisms of hepatitis B virus (HBV) reactivation after hepatitis C virus (HCV) elimination by direct-acting antiviral (DAA) treatment in HBV/HCV-co-infected…”
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Mcl-1 expression is a predictive marker of response to gemcitabine plus nab-paclitaxel for metastatic pancreatic cancer by Urabe, Makiko, Ikezawa, Kenji, Seiki, Yusuke, Watsuji, Ko, Kawamoto, Yasuharu, Hirao, Takeru, Kai, Yugo, Takada, Ryoji, Yamai, Takuo, Mukai, Kaori, Nakabori, Tasuku, Uehara, Hiroyuki, Nagata, Shigenori, Ohkawa, Kazuyoshi

“…Antiapoptotic protein, including Mcl-1, expression is frequently observed in pancreatic cancer. Gemcitabine plus nabpaclitaxel (GnP) is the standard…”
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Clinical significance of germline breast cancer susceptibility gene (gBRCA) testing and olaparib as maintenance therapy for patients with pancreatic cancer by Kawamoto, Yasuharu, Yamai, Takuo, Ikezawa, Kenji, Seiki, Yusuke, Watsuji, Ko, Hirao, Takeru, Urabe, Makiko, Kai, Yugo, Takada, Ryoji, Mukai, Kaori, Nakabori, Tasuku, Uehara, Hiroyuki, Inoue, Tazuko, Fujisawa, Fumie, Ohkawa, Kazuyoshi

“…Germline breast cancer susceptibility gene (gBRCA) mutation in patients with pancreatic cancer (PC) is not common in clinical practice. Therefore, factors that…”
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Early detection of venous thromboembolism after the initiation of chemotherapy predicts a poor prognosis in patients with unresectable metastatic pancreatic cancer who underwent first-line chemotherapy with gemcitabine plus nab-paclitaxel by Yamai, Takuo, Ikezawa, Kenji, Hiraga, Erika, Kawamoto, Yasuharu, Hirao, Takeru, Higashi, Sena, Daiku, Kazuma, Maeda, Shingo, Abe, Yutaro, Urabe, Makiko, Kai, Yugo, Takada, Ryoji, Nakabori, Tasuku, Fukutake, Nobuyasu, Uehara, Hiroyuki, Fujita, Masashi, Ohkawa, Kazuyoshi

“…Pancreatic cancer is associated with a high thromboembolism risk. We investigated the significance of early venous thromboembolism (VTE) detection in patients…”
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Parallel administration of nanoliposomal irinotecan and levo-leucovorin for pancreatic cancer by Takada, Ryoji, Ikezawa, Kenji, Yamai, Takuo, Watsuji, Ko, Seiki, Yusuke, Kawamoto, Yasuharu, Hirao, Takeru, Higashi, Sena, Urabe, Makiko, Kai, Yugo, Nakabori, Tasuku, Uehara, Hiroyuki, Kotani, Michiyo, Yagi, Toshinari, Kimura, Miho, Nozaki, Keisuke, Takagi, Mari, Ohkawa, Kazuyoshi

“…Nanoliposomal irinotecan (nal-IRI) plus 5-fluorouracil (5-FU)/levo-leucovorin (Levo-LV) was approved for unresectable pancreatic cancer (UR-PC) in March 2020…”
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Hepatitis C virus enhances Rubicon expression, leading to autophagy inhibition and intracellular innate immune activation by Shiode, Yuto, Hikita, Hayato, Tanaka, Satoshi, Shirai, Kumiko, Doi, Akira, Sakane, Sadatsugu, Kai, Yugo, Nakabori, Tasuku, Yamada, Ryoko, Kodama, Takahiro, Narumi, Ryohei, Sakamori, Ryotaro, Eguchi, Hidetoshi, Tomonaga, Takeshi, Tatsumi, Tomohide, Takehara, Tetsuo

“…Autophagy, a degradation system, works to maintain cellular homeostasis. However, as the impact of Hepatitis C virus (HCV) infection on hepatocyte autophagy…”
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Feasibility of atezolizumab and bevacizumab combination regimens in patients with hepatocellular carcinoma and lung cancer taking direct oral anticoagulants by Nakabori, Tasuku, Kunimasa, Kei, Kawabata, Masaki, Higashi, Sena, Mukai, Kaori, Kawamura, Takahisa, Inoue, Takako, Tamiya, Motohiro, Nishino, Kazumi, Ohkawa, Kazuyoshi

“…Aim Atezolizumab and bevacizumab (Atezo/Bev) combination immunotherapy regimens and direct oral anticoagulants (DOACs) are both associated with bleeding…”
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Focally Spared Region in Diffuse Type of Liver Metastasis From Renal Cell Carcinoma by Nakabori, Tasuku, Abe, Yutaro, Honma, Keiichiro, Ohkawa, Kazuyoshi

“…Liver metastasis is not uncommon in various malignant tumors. Most of liver metastases present as discrete masses. However, liver metastases can appear as…”
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Safety and Feasibility of Combining On-Demand Selective Locoregional Treatment with First-Line Atezolizumab Plus Bevacizumab for Patients with Unresectable Hepatocellular Carcinoma by Nakabori, Tasuku, Higashi, Sena, Abe, Yutaro, Mukai, Kaori, Ikawa, Toshiki, Konishi, Koji, Maeda, Noboru, Nakanishi, Katsuyuki, Hasegawa, Shinichiro, Wada, Hiroshi, Ohkawa, Kazuyoshi

“…Various locoregional treatments for localized hepatocellular carcinoma (HCC) have been developed. This retrospective study investigated the safety and…”
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Establishment of preanalytical conditions for microRNA profile analysis of clinical plasma samples by Suzuki, Kuno, Yamaguchi, Tatsuya, Kohda, Masakazu, Tanaka, Masami, Takemura, Hiroyuki, Wakita, Mitsuru, Tabe, Yoko, Kato, Shunsuke, Nasu, Motomi, Hashimoto, Takashi, Mine, Shinji, Serizawa, Nobuko, Tomishima, Ko, Nagahara, Akihito, Matsuda, Takahisa, Yamaji, Taiki, Tsugane, Shoichiro, Saito, Yutaka, Daiko, Hiroyuki, Yoshikawa, Takaki, Kato, Ken, Okusaka, Takuji, Ochiya, Takahiro, Yamamoto, Yusuke, Yotsui, Shoji, Yamamoto, Takashi, Yamasaki, Tomoyuki, Miyata, Hiroshi, Yasui, Masayoshi, Omori, Takeshi, Ohkawa, Kazuyoshi, Ikezawa, Kenji, Nakabori, Tasuku, Sugimoto, Naotoshi, Kudo, Toshihiro, Yoshida, Keiichi, Ohue, Masayuki, Nishizawa, Takashi

“…The relationship between the expression of microRNAs (miRNAs) in blood and a variety of diseases has been investigated. MiRNA-based liquid biopsy has attracted…”
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An age-group analysis on the efficacy of chemotherapy in older adult patients with metastatic biliary tract cancer: a Japanese cancer registry cohort study by Hirao, Takeru, Ikezawa, Kenji, Morishima, Toshitaka, Daiku, Kazuma, Seiki, Yusuke, Watsuji, Ko, Kawamoto, Yasuharu, Higashi, Sena, Urabe, Makiko, Kai, Yugo, Takada, Ryoji, Yamai, Takuo, Mukai, Kaori, Nakabori, Tasuku, Uehara, Hiroyuki, Miyashiro, Isao, Ohkawa, Kazuyoshi

“…The effectiveness of chemotherapy in older adult patients with biliary tract cancer (BTC) remains to be established, despite the fact that the majority of…”
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A case of refractory tumor bleeding from an ampullary adenocarcinoma: Compression hemostasis with a self‐expandable metallic stent by Daiku, Kazuma, Ikezawa, Kenji, Maeda, Shingo, Abe, Yutaro, Kai, Yugo, Takada, Ryoji, Yamai, Takuo, Fukutake, Nobuyasu, Nakabori, Tasuku, Uehara, Hiroyuki, Ohkawa, Kazuyoshi

“…Although patients with ampullary cancers frequently experience obstructive jaundice and tumor bleeding, there have been few reports on efficient management of…”
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5-Fluorouracil/L-Leucovorin Plus Oxaliplatin (FOLFOX) Regimen as Salvage Chemotherapy for Patients with Unresectable Pancreatic Cancer Receiving Gemcitabine and Nab-Paclitaxel and 5-Fluorouracil/L-Leucovorin Plus Nanoliposomal Irinotecan: Preliminary Results from Clinical Practice by Yamai, Takuo, Ikezawa, Kenji, Kawamoto, Yasuharu, Hirao, Takeru, Higashi, Sena, Daiku, Kazuma, Maeda, Shingo, Abe, Yutaro, Urabe, Makiko, Kai, Yugo, Takada, Ryoji, Nakabori, Tasuku, Uehara, Hiroyuki, Ohkawa, Kazuyoshi

“…Salvage chemotherapy for patients with unresectable pancreatic cancer (UR-PC) who have been treated with gemcitabine and nab-paclitaxel (GnP), and…”
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Immunological responses against hepatitis B virus in human peripheral blood mononuclear cell-engrafted mice by Aono, Satoshi, Tatsumi, Tomohide, Yoshioka, Teppei, Tawara, Seiichi, Nishio, Akira, Onishi, Yoshiki, Fukutomi, Keisuke, Nakabori, Tasuku, Kodama, Takahiro, Shigekawa, Minoru, Hikita, Hayato, Sakamori, Ryotaro, Takahashi, Takeshi, Suemizu, Hiroshi, Takehara, Tetsuo

“…It is well known that immune-mediated virus elimination is necessary for the treatment of HBV infection. Reconstitution of human immune cells in liver chimeric…”
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Oil blotting paper for formalin fixation increases endoscopic ultrasound‐guided tissue acquisition‐collected sample volumes on glass slides by Yamai, Takuo, Ikezawa, Kenji, Seiki, Yusuke, Watsuji, Ko, Kawamoto, Yasuharu, Hirao, Takeru, Daiku, Kazuma, Maeda, Shingo, Urabe, Makiko, Kai, Yugo, Takada, Ryoji, Mukai, Kaori, Nakabori, Tasuku, Uehara, Hiroyuki, Tsuzaki, Sayoko, Ryu, Ayumi, Tanada, Satoshi, Nagata, Shigenori, Ohkawa, Kazuyoshi

“…Objectives Endoscopic ultrasound‐guided tissue acquisition (EUS‐TA) is used for pathological diagnosis and obtaining samples for molecular testing,…”
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Baseline quasispecies selection and novel mutations contribute to emerging resistance-associated substitutions in hepatitis C virus after direct-acting antiviral treatment by Kai, Yugo, Hikita, Hayato, Morishita, Naoki, Murai, Kazuhiro, Nakabori, Tasuku, Iio, Sadaharu, Hagiwara, Hideki, Imai, Yasuharu, Tamura, Shinji, Tsutsui, Syusaku, Naito, Masafumi, Nishiuchi, Meiko, Kondo, Yasuteru, Kato, Takanobu, Suemizu, Hiroshi, Yamada, Ryoko, Oze, Tsugiko, Yakushijin, Takayuki, Hiramatsu, Naoki, Sakamori, Ryotaro, Tatsumi, Tomohide, Takehara, Tetsuo

“…Resistance-associated substitutions (RASs) in hepatitis C virus (HCV) appear upon failure of treatment with direct-acting antivirals (DAAs). However, their…”
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Usefulness of on‐site cytology of liver tumor biopsy in specimen sampling for cancer genomic profiling test by Nakabori, Tasuku, Abe, Yutaro, Higashi, Sena, Mukai, Kaori, Yoshioka, Risa, Morimoto, Yuki, Koyanagi, Yuki, Tanada, Satoshi, Nagata, Shigenori, Honma, Keiichiro, Ohkawa, Kazuyoshi

“…Aim Appropriate sample selection with a tumor fraction ≥20% without necrosis contamination is required for successful cancer genomic profiling (CGP). Rapid…”
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Portal Vein Aneurysm in a Patient with Cirrhosis Type C Controlled by Direct-Acting Antiviral Treatment by Higashi, Sena, Nakabori, Tasuku, Mukai, Kaori, Seiki, Yusuke, Watsuji, Ko, Hirao, Takeru, Kawamoto, Yasuharu, Urabe, Makiko, Kai, Yugo, Takada, Ryoji, Yamai, Takuo, Ikezawa, Kenji, Uehara, Hiroyuki, Ohkawa, Kazuyoshi

“…Abstract Introduction: Portal vein aneurysm (PVA) is a rare saccular or fusiform portal vein dilatation. The management and optimal treatment of PVA remain…”
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Sensitivity of cytology in liver tumor biopsy and its significance in the prompt clinical diagnosis of non‐hepatocellular carcinoma by Nakabori, Tasuku, Abe, Yutaro, Higashi, Sena, Mukai, Kaori, Shingetsu, Azusa, Nishimura, Sanako, Tsuzaki, Sayoko, Ryu, Ayumi, Tanada, Satoshi, Nagata, Shigenori, Honma, Keiichiro, Ohkawa, Kazuyoshi

“…Background Cytology is a fast and simple modality for identifying malignancies and tumor histology. In this study, we analyzed the sensitivity of cytology for…”
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