Search Results - "Taskintuna, Kaan"
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PGC-1α repression dysregulates lipid metabolism and induces lipid droplet accumulation in the retinal pigment epithelium
Published in Cell death & disease (01-06-2024)“…Drusen, the yellow deposits under the retina, are composed of lipids and proteins, and represent a hallmark of age-related macular degeneration (AMD). Lipid…”
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Sex-dependent regulation of retinal pigment epithelium and retinal function by Pgc-1α
Published in Frontiers in cellular neuroscience (02-09-2024)“…Age-related macular degeneration (AMD) is a major cause of blindness that affects people over 60. While aging is the prominent factor in AMD, studies have…”
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The Anti-Aging Hormone Klotho Promotes Retinal Pigment Epithelium Cell Viability and Metabolism by Activating the AMPK/PGC-1α Pathway
Published in Antioxidants (01-02-2023)“…Initially discovered by Makuto Kuro-o in 1997, Klotho is a putative aging-suppressor gene when overexpressed and accelerates aging when deleted in mice…”
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Comparison of outcomes of four different treatment modalities for diabetic vitreous haemorrhage
Published in Scientific reports (28-02-2020)“…We compared outcomes of four different management modalities for diabetic VH. Patients with diabetic VH were identified in this retrospective study undertaken…”
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Abstract 4126304: A Cardiac Targeting Peptide Linked to miRNA106a Targets and Suppresses Genes Known to Cause Heart Failure: Reversing Heart Failure at the Source
Published in Circulation (New York, N.Y.) (12-11-2024)“…Abstract only Background: About one in five adults at age 40 will develop heart failure (HF) during their lifetime. Risk factors for HF (e.g., hypertension,…”
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