Search Results - "Taskén, K."

Low Expression of miR-424-3p is Highly Correlated with Clinical Failure in Prostate Cancer by Richardsen, E., Andersen, S., Al-Saad, S., Rakaee, M., Nordby, Y., Pedersen, M. I., Ness, N., Ingebriktsen, L. M., Fassina, A., Taskén, K. A., Mills, I. G., Donnem, T., Bremnes, R. M., Busund, L. T.

“…Prostate cancer (PC) is a highly heterogenous disease and one of the leading causes of mortality in developed countries. Recently, studies have shown that…”
Get full text

Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia by Ånensen, N, Hjelle, S M, Van Belle, W, Haaland, I, Silden, E, Bourdon, J-C, Hovland, R, Taskén, K, Knappskog, S, Lønning, P E, Bruserud, Ø, Gjertsen, B T

“…The wild-type tumor-suppressor gene TP53 encodes several isoforms of the p53 protein. However, while the role of p53 in controlling normal cell cycle…”
Get full text

Autologous bone marrow Th cells can support multiple myeloma cell proliferation in vitro and in xenografted mice by Wang, D, Fløisand, Y, Myklebust, C V, Bürgler, S, Parente-Ribes, A, Hofgaard, P O, Bogen, B, Taskén, K, Tjønnfjord, G E, Schjesvold, F, Dalgaard, J, Tveita, A, Munthe, L A

“…Multiple myeloma (MM) is a plasma cell malignancy where MM cell growth is supported by the bone marrow (BM) microenvironment with poorly defined cellular and…”
Get full text

Killer immunoglobulin-like receptors (KIRS) on 3rd trimester decidual natural killer cells by Johnsen, G.M, Sheng, V.O.Y, Taskén, K, Staff, A.C, Malmberg, K.J

Get full text

P626: FUNCTIONAL SCREENING OF PI3K INHIBITORS STRATIFIES RESPONDERS TO IDELALISIB AND INDICATES DRUG CLASS ACTIVITY IN IDELALISIB‐REFRACTORY CLL by Skånland, S., Yanping, Y., Athanasiadis, P., Karlsen, L., Urban, A., Murali, I., Fernandes, S., Hilli, A., Taskén, K., Bertoni, F., Mato, A., Normant, E., Brown, J., Tjønnfjord, G., Aittokallio, T.

Get full text

Compartmentalization of cAMP signaling in adipogenesis, lipogenesis, and lipolysis by Rogne, M, Taskén, K

“…Energy storage and release at times of food excess or fasting are carefully coordinated processes that depend on the appropriate differentiation of mesenchymal…”
Get more information

Expression of Serotonin Receptors 2B and 4 in Human Prostate Cancer Tissue and Effects of Their Antagonists on Prostate Cancer Cell Lines by Dizeyi, N., Bjartell, A., Hedlund, P., Taskén, K.A., Gadaleanu, V., Abrahamsson, P-A.

“…Overexpression of receptors to neuroendocrine (NE) cell products has been suggested to contribute to development of hormone-refractory prostate cancer (HRPC)…”
Get full text

Molecular architecture of signal complexes regulating immune cell function by Torgersen, K M, Aandahl, E M, Taskén, K

“…Signals transmitted via multichain immunoreceptors control the development, differentiation and activation of hematopoetic cells. The cytoplasmic parts of…”
Get more information

Compartmentalized cAMP signalling is important in the regulation of Ca(2+) cycling in the heart by Lygren, B, Taskén, K

“…Co-ordinated myocyte handling of calcium is essential for efficient excitation-contraction coupling in the heart. The calcium cycling activity can be modulated…”
Get more information

Multiplexed phosphospecific flow cytometry enables large‐scale signaling profiling and drug screening in blood platelets by Spurgeon, B. E. J., Aburima, A., Oberprieler, N. G., Taskén, K., Naseem, K. M.

“…Summary Background Dissecting the signaling events that contribute to platelet activation will increase our understanding of platelet function and aid in the…”
Get full text

Targeting of type I protein kinase A to lipid rafts is required for platelet inhibition by the 3′,5′‐cyclic adenosine monophosphate‐signaling pathway by Raslan, Z., Magwenzi, S., Aburima, A., Taskén, K., Naseem, K. M.

“…Summary Background Platelet adhesion to von Willebrand factor (VWF) is modulated by 3′,5′‐cyclic adenosine monophosphate (cAMP) signaling through protein…”
Get full text

Review: Spatiotemporal dynamics of hCG/cAMP signaling and regulation of placental function by Weedon-Fekjær, M.S, Taskén, K

“…Abstract The pregnancy hormone human chorionic gonadotropin (hCG) is essential to sustain early pregnancy and involved in regulation of progesterone…”
Get full text

Spatiotemporal control of cAMP signalling processes by anchored signalling complexes by Jarnaess, E, Taskén, K

“…Ligand-induced changes in cAMP concentration vary in duration, amplitude and extension into the cell. cAMP microdomains are shaped by adenylate cyclases that…”
Get more information

The molecular machinery for cAMP-dependent immunomodulation in T-cells by Taskén, K, Stokka, A J

“…cAMP inhibits Src-family kinase signalling by PKA (protein kinase A)-mediated phosphorylation and activation of Csk (C-terminal Src kinase). The PKA type I-Csk…”
Get more information

Mechanisms for cardiac dysfunction in COPD and respiratory failure by Larsen, K.O, Lygren, B, Sjaastad, I, Krobert, K.A, Arnkværn, K, Florholmen, G, Levy, F.O, Taskén, K, Christensen, G, Skjønsberg, O.H

Get full text

Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma by Nyakas, M., Aamdal, E., Jacobsen, K. D., Guren, T. K., Aamdal, S., Hagene, K. T., Brunsvig, P., Yndestad, A., Halvorsen, B., Tasken, K. A., Aukrust, P., Mælandsmo, G. M., Ueland, T.

“…Summary New therapies, including the anti‐cytotoxic T lymphocyte antigen (CTLA)‐4 antibody, ipilimumab, is approved for metastatic melanoma. Prognostic…”
Get full text

Phosphodiesterase 4D and Protein Kinase A Type II Constitute a Signaling Unit in the Centrosomal Area by Taskén, Kristin A., Collas, Philippe, Kemmner, Wolfram A., Witczak, Oliwia, Conti, Marco, Taskén, Kjetil

“…The mediation of cAMP effects by specific pools of protein kinase A (PKA) targeted to distinct subcellular domains raises the question of how inactivation of…”
Get full text

Increased PP1 and PP2A mediating reduced Ser16 phosphorylated PLB is a possible mechanism for cardiac dysfunction in alveolar hypoxia by Larsen, K.-O, Lygren, B, Sjaastad, I, Krobert, K.A, Florholmen, G, Arnkværn, K, Levy, F.O, Skjønsberg, O.H, Taskén, K, Christensen, G

Get full text

Combined Env- and Gag-specific T cell responses in relation to programmed death-1 receptor and CD4⁺ T cell loss rates in human immunodeficiency virus-1 infection by Pettersen, F.O, Taskén, K, Kvale, D

“…Additional progression markers for human immunodeficiency virus (HIV) infection are warranted. In this study we related antigen-specific responses in CD4⁺ and…”
Get full text

Molecular Cloning, cDNA Structure, and Chromosomal Localization of the Human Type II cGMP-Dependent Protein Kinase by Ørstavik, S, Solberg, R, Taskén, K, Nordahl, M, Altherr, M.R, Hansson, V, Jahnsen, T, Sandberg, M

“…The type II cGMP-dependent protein kinase is an enzyme originally isolated from the small intestine, and is thought to be involved in the regulation of…”
Get full text