Search Results - "Tasinato, Elena"

Comparison of the Impact of VRP-034 and Polymyxin B upon Markers of Kidney Injury in Human Proximal Tubule Monolayers In Vitro by Pye, Keith, Tasinato, Elena, Shuttleworth, Siannah, Devlin, Claire, Brown, Colin

“…In this study, we assessed the impact of commercially available polymyxin B against VRP-034 (novel formulation of polymyxin B) using a validated in vitro human…”
Get full text

Development of a Highly Differentiated Human Primary Proximal Tubule MPS Model (aProximate MPS Flow) by Pisapia, Francesca, O'Brien, Donovan, Tasinato, Elena, Garner, Kathryn L, Brown, Colin D A

“…The kidney proximal tubule (PT) mediates renal drug elimination in vivo and is a major site of drug-induced toxicity. To reliably assess drug efficacy, it is…”
Get full text

Direct transcriptomic comparison of xenobiotic metabolism and toxicity pathway induction of airway epithelium models at an air–liquid interface generated from induced pluripotent stem cells and primary bronchial epithelial cells by Djidrovski, Ivo, Georgiou, Maria, Tasinato, Elena, Leonard, Martin O., Van den Bor, Jelle, Lako, Majlinda, Armstrong, Lyle

“…The airway epithelium represents the main barrier between inhaled air and the tissues of the respiratory tract and is therefore an important point of contact…”
Get full text