Search Results - "Tas, S W"

Spinning straw into gold: description of a disruptive rheumatology research platform inspired by the COVID-19 pandemic by Boekel, L, Hooijberg, F, Vogelzang, E H, Klarenbeek, P L, Bos, W H, Tas, S W, Wolbink, G J

“…Clinical research projects often use traditional methods in which data collection and signing informed consent forms rely on patients' visits to the research…”
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Dysregulated endothelial cell markers in systemic lupus erythematosus: a systematic review and meta-analysis by Bergkamp, S C, Wahadat, M J, Salah, A, Kuijpers, T W, Smith, V, Tas, S W, van den Berg, J M, Kamphuis, S, Schonenberg-Meinema, D

“…To perform a systematic literature review and meta-analysis on endothelial cell (EC) markers that are involved and dysregulated in systemic lupus erythematosus…”
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IgG4:IgG RNA ratio differentiates active disease from remission in granulomatosis with polyangiitis: a new disease activity marker? A cross-sectional and longitudinal study by Al-Soudi, A, Doorenspleet, M E, Esveldt, R E, Burgemeister, L T, Hak, A E, van den Born, B J H, Tas, S W, van Vollenhoven, R F, Klarenbeek, P L, de Vries, N

“…An important limitation in granulomatosis with polyangiitis (GPA) is the lack of disease activity markers. Immunoglobulin G4-positive (IgG4 ) B cells and…”
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Evidence for a pathogenic role of extrafollicular, IL-10–producing CCR6⁺B helper T cells in systemic lupus erythematosus by Facciotti, F., Larghi, P., Bosotti, R., Vasco, C., Gagliani, N., Cordiglierif, C., Mazzarag, S., Ranzani, V., Rottoli, E., Curti, S., Penatti, A., Karnani, B., Kobayashi, Y., Crosti, M., Bombaci, M., van Hamburg, J. P., Rossetti, G., Gualtierotti, R., Gerosa, M., Gatti, S., Torretta, S., Pignataro, L., Tas, S. W., Abrignani, S., Pagani, M., Grassi, F., Meroni, P. L., Flavell, R. A., Geginat, J.

“…Interleukin 10 (IL-10) is an antiinflammatory cytokine, but also promotes B cell responses and plays a pathogenic role in systemic lupus erythematosus (SLE)…”
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Macrophages from patients with SLE and rheumatoid arthritis have defective adhesion in vitro, while only SLE macrophages have impaired uptake of apoptotic cells by Tas, S W, Quartier, P, Botto, M, Fossati-Jimack, L

“…Background: It has been suggested that defective handling of apoptotic cells by macrophages plays a key role in the development of systemic lupus erythematosus…”
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Endothelial cells: From innocent bystanders to active participants in immune responses by Al-Soudi, A., Kaaij, M.H., Tas, S.W.

“…The endothelium is crucially important for the delivery of oxygen and nutrients throughout the body under homeostatic conditions. However, it also contributes…”
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Enhanced gene transfer to arthritic joints using adeno-associated virus type 5: implications for intra-articular gene therapy by Adriaansen, J, Tas, S W, Klarenbeek, P L, Bakker, A C, Apparailly, F, Firestein, G S, Jorgensen, C, Vervoordeldonk, M J B M, Tak, P P

“…Background: Gene therapy of the joint has great potential as a new therapeutic approach for the treatment of rheumatoid arthritis (RA). The vector chosen is of…”
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IL-10 producing regulatory and helper T-cells in systemic lupus erythematosus by Geginat, J., Vasco, M., Gerosa, M., Tas, S.W., Pagani, M., Grassi, F., Flavell, R.A., Meroni, Pl, Abrignani, S.

“…•IL-10 has a dual role in immune responses.•IL-10 is increased in lupus, promotes autoantibody production and is evaluated as a therapeutic target in SLE…”
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Longitudinal humoral response after SARS-CoV-2 vaccination in ocrelizumab treated MS patients: To wait and repopulate? by van Kempen, Z.L.E., Wieske, L., Stalman, E.W., Kummer, L. Y. L, van Dam, P.J., Volkers, A.G., Boekel, L., Toorop, A.A., Strijbis, E.M.M., Tas, S.W., Wolbink, G.J., Löwenberg, M., van Sandt, C., ten Brinke, A., Verstegen, N.J.M., Steenhuis, M., Kuijpers, T.W., van Ham, S.M., Rispens, T., Eftimov, F., Killestein, J.

“…The objective of this study was to measure humoral responses after SARS-CoV-2 vaccination in MS patients treated with ocrelizumab (OCR) compared to MS patients…”
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Biologics for rare inflammatory diseases: TNF blockade in the SAPHO syndrome by BURGEMEISTER, L. T, BAETEN, D. L. P, TAS, S. W

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Ticking the right boxes: classification of patients suspected of Lyme borreliosis at an academic referral center in the Netherlands by Coumou, J., Herkes, E.A., Brouwer, M.C., van de Beek, D., Tas, S.W., Casteelen, G., van Vugt, M., Starink, M.V., de Vries, H.J.C., de Wever, B., Spanjaard, L., Hovius, J.W.R.

“…To provide better care for patients suspected of having Lyme borreliosis (LB) we founded the Amsterdam Multidisciplinary Lyme borreliosis Center (AMLC). The…”
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A Dutch consensus statement on the diagnosis and treatment of ANCA-associated vasculitis by Dirikgil, E, Tas, S W, Rutgers, A, Verhoeven, P M J, van Laar, J M, Hagen, E C, Tekstra, J, L Hak, A E, van Paassen, P, Kok, M R, Goldschmeding, R, van Dam, B, Douma, C E, Remmelts, H H F, Sanders, J F, Jonker, J T, Rabelink, T J, Damoiseaux, J G M C, Bernelot Moens, H J, J W Bos, W, Teng, Y K O

“…Despite the availability of several guidelines on the diagnosis and treatment of antineutrophil cytoplasmic antibody-associated vasculitis (AAV), clinical…”
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Personalised treatment of arthritis in the next eRA by Tas, S W

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Inhibition of forkhead box class O family member transcription factors in rheumatoid synovial tissue by Ludikhuize, J., de Launay, D., Groot, D., Smeets, T. J. M., Vinkenoog, M., Sanders, M. E., Tas, S. W., Tak, P. P., Reedquist, K. A.

“…Objective Phosphatidylinositol 3‐kinase–dependent activation of protein kinase B (PKB) has been observed in rheumatoid arthritis (RA) synovial tissue, and…”
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C1q and C4b Bind Simultaneously to CR1 and Additively Support Erythrocyte Adhesion by Tas, Sander W, Klickstein, Lloyd B, Barbashov, Sergei F, Nicholson-Weller, Anne

“…Previously, we showed that soluble C1q bound specifically to CR1 on transfected cells. If the CR1-C1q interaction were to participate in immune complex…”
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ERN ReCONNET points to consider for treating patients living with autoimmune rheumatic diseases with antiviral therapies and anti-SARS-CoV-2 antibody products by Talarico, Rosaria, Ramirez, Giuseppe Alvise, Barreira, Sofia C, Cardamone, Chiara, Triggianese, Paola, Aguilera, Silvia, Andersen, Jeanette, Avcin, Tadej, Benistan, Karelle, Bertsias, George, Bortoluzzi, Alessandra, Bouillot, Coralie, Bulina, Inita, Burmester, Gerd R, Callens, Steven, Carreira, Patricia E, Cervera, Ricard, Cutolo, Maurizio, Damian, Laura, Della-Torre, Emanuel, Faria, Raquel, Fonseca, João E, Galetti, Ilaria, Hachulla, Eric, Iaccarino, Luca, Jacobsen, Søren, Khmelinskii, Nikita, Limper, Maarten, Marinello, Diana, Meyer, Alain, Moroncini, Gianluca, Nagy, Gyorgy, Olesinska, Marzena, Pamfil, Cristina, Pileckyte, Margarita, Pistello, Mauro, Rednic, Simona, Richez, Christophe, Romão, Vasco C, Schneider, Matthias, Sciascia, Savino, Scirè, Carlo Alberto, Simonini, Gabriele, Smith, Vanessa, Sulli, Alberto, Tani, Chiara, Tas, Sander W, Tincani, Angela, Vonk, Madelon C, Tektonidou, Maria, Mosca, Marta

“…Recent studies have shown that people who are immunocompromised may inadvertently play a role in spurring the mutations of the virus that create new variants…”
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Effects of B-cell directed therapy on the preclinical stage of rheumatoid arthritis: the PRAIRI study by Gerlag, Danielle M, Safy, Mary, Maijer, Karen I, Tang, Man Wai, Tas, Sander W, Starmans-Kool, Mirian J F, van Tubergen, Astrid, Janssen, Matthijs, de Hair, Maria, Hansson, Monika, de Vries, Niek, Zwinderman, Aeilko H, Tak, Paul P

“…We explored the effects of B-cell directed therapy in subjects at risk of developing autoantibodypositive rheumatoid arthritis (RA), who never experienced…”
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Ticking the right boxes: classification of patients suspected of Lyme borreliosis at an academic referral center in the Netherlands: Infectious diseases by Coumou, J, Herkes, E A, Brouwer, M C, van de Beek, D, Tas, S W, Casteelen, G, van Vugt, M, Starink, M V, de Vries, HJC, de Wever, B, Spanjaard, L, Hovius, JWR

“…To provide better care for patients suspected of having Lyme borreliosis (LB) we founded the Amsterdam Multidisciplinary Lyme borreliosis Center (AMLC). The…”
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Complement receptor 1/CD35 is a receptor for mannan-binding lectin by Ghiran, I, Barbashov, S F, Klickstein, L B, Tas, S W, Jensenius, J C, Nicholson-Weller, A

“…Mannan-binding lectin (MBL), a member of the collectin family, is known to have opsonic function, although identification of its cellular receptor has been…”
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SARS-CoV-2 omicron breakthrough infections in patients with multiple sclerosis by van Kempen, Zoé L E, Stalman, Eileen W, Steenhuis, Maurice, Kummer, Laura Y L, van Dam, Koos P J, Wilbrink, Maarten F, ten Brinke, Anja, van Ham, S Marieke, Kuijpers, Taco, Rispens, Theo, Eftimov, Filip, Wieske, Luuk, Killestein, Joep, vd Kooi, AJ, Raaphorst, J, Koos Zwinderman, AH, Löwenberg, M, Volkers, AG, D'Haens, G.R.A.M, Takkenberg, RB, Tas, SW, Spuls, PI, Bekkenk, MW, Musters, AH, Post, NF, Bosma, AL, Hilhorst, ML, Vegting, Y, Bemelman, FJ, Verstegen, N.J.M., Fernandez, L, Keijzer, S, Keijser, J.B.D., Cristianawati, O, Voskuyl, AE, Broens, B, Sanchez, AP, Nejentsev, S, Mirfazeli, ES, Wolbink, GJ, Boekel, L, Rutgers, BA, de Leeuw, K, Horváth, B, Verschuuren, J.J.G.M., Ruiter, A.M, van Ouwerkerk, L, van der Woude, D, Allaart, RCF, Teng, YKO, Busch, MH, Brusse, E., van Doorn, PA, Baars, MAE, Hijnen, DJ, Schreurs, CRG, van der Pol, WL, Goedee, HS, van Els, C.A.C.M, de Wit, J

“…BackgroundIt is unclear which patients with multiple sclerosis (MS) are most susceptible for omicron breakthrough infections.MethodsWe assessed omicron…”
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