Search Results - "Tarsa, Peter"

BET bromodomain inhibitors regulate keratinocyte plasticity by Schutzius, Gabi, Kolter, Christian, Bergling, Sebastian, Tortelli, Federico, Fuchs, Florian, Renner, Steffen, Guagnano, Vito, Cotesta, Simona, Rueeger, Heinrich, Faller, Michael, Bouchez, Laure, Salathe, Adrian, Nigsch, Florian, Richards, Shola M., Louis, Malvina, Gruber, Viktoria, Aebi, Alexandra, Turner, Jonathan, Grandjean, Frederic, Li, Jun, Dimitri, Chris, Thomas, Jason R., Schirle, Markus, Blank, Jutta, Drueckes, Peter, Vaupel, Andrea, Tiedt, Ralph, Manley, Paul W., Klopp, Julia, Hemmig, Rene, Zink, Florence, Leroy, Nelly, Carbone, Walter, Roma, Guglielmo, Keller, Caroline Gubser, Dales, Natalie, Beyerbach, Armin, Zimmerlin, Alfred, Bonenfant, Debora, Terranova, Remi, Berwick, Amy, Sahambi, Sukhdeep, Reynolds, Aimee, Jennings, Lori L., Ruffner, Heinz, Tarsa, Peter, Bouwmeester, Tewis, Driver, Vickie, Frederiksen, Mathias, Lohmann, Felix, Kirkland, Susan

“…Although most acute skin wounds heal rapidly, non-healing skin ulcers represent an increasing and substantial unmet medical need that urgently requires…”
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Interlaced Optical Force-Fluorescence Measurements for Single Molecule Biophysics by Brau, Ricardo R., Tarsa, Peter B., Ferrer, Jorge M., Lee, Peter, Lang, Matthew J.

“…Combining optical tweezers with single molecule fluorescence offers a powerful technique to study the biophysical properties of single proteins and molecules…”
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Detecting Force-Induced Molecular Transitions with Fluorescence Resonant Energy Transfer by Tarsa, Peter B., Brau, Ricardo R., Barch, Mariya, Ferrer, Jorge M., Freyzon, Yelena, Matsudaira, Paul, Lang, Matthew J.

“…Don't FRET: The first successful combination of optical‐tweezers force microscopy and single‐molecule fluorescence resonant energy transfer (FRET) is…”
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The influence of aqueous content in small scale salt screening—Improving hit rate for weakly basic, low solubility drugs by Tarsa, Peter B., Towler, Christopher S., Woollam, Grahame, Berghausen, Jörg

“…Salt screening and selection is a well established approach for improving the properties of drug candidates, including dissolution rate and bioavailability…”
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Trace Moisture Detection Using Continuous-Wave Cavity Ring-Down Spectroscopy by Dudek, John B, Tarsa, Peter B, Velasquez, Armando, Wladyslawski, Mark, Rabinowitz, Paul, Lehmann, Kevin K

“…We have developed an instrument to measure trace concentrations of small hydride species in gases using continuous-wave cavity ring-down spectroscopy with…”
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Single-cell detection by cavity ring-down spectroscopy by Tarsa, Peter B., Wist, Aislyn D., Rabinowitz, Paul, Lehmann, Kevin K.

“…The implementation of cavity ring-down spectroscopy in an optical fiber resonator extends the viability of this highly sensitive technique for label-free…”
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Evanescent field absorption in a passive optical fiber resonator using continuous-wave cavity ring-down spectroscopy by Tarsa, Peter B., Rabinowitz, Paul, Lehmann, Kevin K.

“…We combine the sensitivity advantages of cavity ring-down spectroscopy (CRDS) with the versatility of optical fiber sensing technology in a spatially extended…”
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The Discovery of N‑(1-Methyl-5-(trifluoromethyl)‑1H‑pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)‑1H‑indole-1-carboxamide (Acrizanib), a VEGFR‑2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration by Adams, Christopher M, Anderson, Karen, Artman, Gerald, Bizec, Jean-Claude, Cepeda, Rosemarie, Elliott, Jason, Fassbender, Elizabeth, Ghosh, Malay, Hanks, Shawn, Hardegger, Leo A, Hosagrahara, Vinayak P, Jaffee, Bruce, Jendza, Keith, Ji, Nan, Johnson, Leland, Lee, Wendy, Liu, Donglei, Liu, Fang, Long, Debby, Ma, Fupeng, Mainolfi, Nello, Meredith, Erik L, Miranda, Karl, Peng, Yao, Poor, Stephen, Powers, James, Qiu, Yubin, Rao, Chang, Shen, Siyuan, Sivak, Jeremy M, Solovay, Catherine, Tarsa, Peter, Woolfenden, Amber, Zhang, Chun, Zhang, Yiqin

“…A noninvasive topical ocular therapy for the treatment of neovascular or “wet” age-related macular degeneration would provide a patient administered…”
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Discovery of Oral VEGFR‑2 Inhibitors with Prolonged Ocular Retention That Are Efficacious in Models of Wet Age-Related Macular Degeneration by Meredith, Erik L, Mainolfi, Nello, Poor, Stephen, Qiu, Yubin, Miranda, Karl, Powers, James, Liu, Donglei, Ma, Fupeng, Solovay, Catherine, Rao, Chang, Johnson, Leland, Ji, Nan, Artman, Gerald, Hardegger, Leo, Hanks, Shawn, Shen, Siyuan, Woolfenden, Amber, Fassbender, Elizabeth, Sivak, Jeremy M, Zhang, Yiqin, Long, Debby, Cepeda, Rosemarie, Liu, Fang, Hosagrahara, Vinayak P, Lee, Wendy, Tarsa, Peter, Anderson, Karen, Elliott, Jason, Jaffee, Bruce

“…The benefit of intravitreal anti-VEGF therapy in treating wet age-related macular degeneration (AMD) is well established. Identification of VEGFR-2 inhibitors…”
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The Discovery of N -(1-Methyl-5-(trifluoromethyl)-1 H -pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1 H -indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration by Adams, Christopher M., Anderson, Karen, Artman, Gerald, Bizec, Jean-Claude, Cepeda, Rosemarie, Elliott, Jason, Fassbender, Elizabeth, Ghosh, Malay, Hanks, Shawn, Hardegger, Leo A., Hosagrahara, Vinayak P., Jaffee, Bruce, Jendza, Keith, Ji, Nan, Johnson, Leland, Lee, Wendy, Liu, Donglei, Liu, Fang, Long, Debby, Ma, Fupeng, Mainolfi, Nello, Meredith, Erik L., Miranda, Karl, Peng, Yao, Poor, Stephen, Powers, James, Qiu, Yubin, Rao, Chang, Shen, Siyuan, Sivak, Jeremy M., Solovay, Catherine, Tarsa, Peter, Woolfenden, Amber, Zhang, Chun, Zhang, Yiqin

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Optical fiber cavity ring-down spectroscopy by Tarsa, Peter Bowie

“…The improved sensitivity of Cavity Ring-down Spectroscopy (CRDS) over traditional molecular absorption spectroscopy techniques has resulted in its widespread…”
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Detecting Force-Induced Molecular Transitions with Fluorescence Resonant Energy Transfer by Tarsa, Peter B., Brau, Ricardo R., Barch, Mariya, Ferrer, Jorge M., Freyzon, Yelena, Matsudaira, Paul, Lang, Matthew J.

“…Erfolgreiche Kombination: Zum ersten Mal gelang es, die Kraftmikroskopie mit optischen Pinzetten und dem resonanten Einzelmolekül‐Fluoreszenz‐Energietransfer…”
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Optical fiber cavity ring -down spectroscopy by Tarsa, Peter Bowie

“…The improved sensitivity of Cavity Ring-down Spectroscopy (CRDS) over traditional molecular absorption spectroscopy techniques has resulted in its widespread…”
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