Search Results - "Tarpley, Jason W"
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Neural substrates for expectation-modulated fear learning in the amygdala and periaqueductal gray
Published in Nature neuroscience (01-08-2010)“…Fear conditioning results from the association that develops between a neutral conditioned stimulus and an aversive unconditioned stimulus (UCS), which is…”
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Transcranial Doppler After Endovascular Treatment to Evaluate Collateral Status and Outcomes in Patients With Large‐Vessel Occlusion
Published in Stroke: vascular and interventional neurology (01-03-2022)“…Background Recent advances in endovascular therapy (EVT) have led to significant improvements in functional outcomes of patients with stroke. However, early…”
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Evaluating Outcome Prediction Models in Endovascular Stroke Treatment Using Baseline, Treatment, and Posttreatment Variables
Published in Stroke: vascular and interventional neurology (01-11-2021)“…Background Statistical models to predict outcomes after endovascular therapy for acute ischemic stroke often incorporate baseline (pretreatment) variables…”
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The behavioral and neuroanatomical effects of IB4-saporin treatment in rat models of nociceptive and neuropathic pain
Published in Brain research (10-12-2004)“…One distinguishing feature of primary afferent neurons is their ability to bind the lectin IB(4). Previous work suggested that neurons in the inner part of…”
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Block of peripheral nerve sodium channels selectively inhibits features of neuropathic pain in rats
Published in Molecular pharmacology (01-03-2006)“…Several sodium channel blockers are used clinically to treat neuropathic pain. However, many patients fail to achieve adequate pain relief from these highly…”
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6
Unilateral Storage of Fear Memories by the Amygdala
Published in The Journal of neuroscience (20-04-2005)“…Pavlovian fear conditioning is an associative learning task in which subjects are trained to respond defensively to a neutral conditioned stimulus (CS) by…”
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COVID-19 Impact on Acute Ischemic Stroke Treatment at 9 Comprehensive Stroke Centers across Los Angeles
Published in Cerebrovascular diseases (Basel, Switzerland) (01-12-2021)“…To describe the impact of COVID-19 on acute cerebrovascular disease care across 9 comprehensive stroke centers throughout Los Angeles County (LAC). Volume of…”
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Discovery of potent and use-dependent sodium channel blockers for treatment of chronic pain
Published in Bioorganic & medicinal chemistry letters (02-06-2005)“…The discovery and structure–activity relationship (SAR) studies of a novel class of sodium channel blockers are disclosed. A new series of voltage-gated sodium…”
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Abstract WP143: Use Of CTP For Evaluation Of EVT Candidates In The Early Time Window (<6 Hours From Lkwt) Does Not Delay EVT T And Use Of CTP Beyond 6 Hours Improves Speed Of EVT
Published in Stroke (1970) (01-02-2023)“…IntroductionComputerized Tomography Perfusion (CTP) improves detection of distal occlusion and aids in patient selection for endovascular therapy (EVT) for…”
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Abstract WP196: Seasonal Variation In Stroke Ischemic Hospitalization: Results From The A Large Health System In Six Western States Of The United States
Published in Stroke (1970) (01-02-2023)“…BackgroundEvidence of seasonal variations in the incidence of stroke is inconsistent with some studies reporting no association and some a significant rise in…”
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Abstract WP29: A Propensity-Matched Analysis of Outcomes for Patients With M2 Branch Occlusions at Endovascular Stroke Centers
Published in Stroke (1970) (01-02-2019)“…Abstract only Introduction: Endovascular therapy (EVT) for Emergent Large Vessel Occlusion (ELVO) is recommended for patients with acute proximal MCA (M1…”
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Abstract WP161: Patients With Lower Stroke Scales Take Longer To Treat With Endovascular Thrombectomy Because Of A Longer Time To Identify Their Lvo Not Because Of Longer Procedural Time: Time To Identify And Triage An Lvo Is More Important Determinant Of Treatment Speed Than Procedural Time
Published in Stroke (1970) (01-02-2022)“…IntroductionThe seminal trials of thrombectomy in 2015/16 enrolled a relatively homogenous population of patients with ICA terminus or M1 occlusion and a…”
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Abstract WMP90: Patients With MEVO Take Longer To Treat With Endovascular Thrombectomy Because Of A Longer Time To Identify Candidates For Therapy (door To Groin Puncture) As Well As Longer Procedural Times (groin Puncture To First Thrombectomy Pass)
Published in Stroke (1970) (01-02-2022)“…IntroductionThe seminal trials of thrombectomy in 2015/16 enrolled a relatively homogenous population of patients with acute ischemic stroke due to ICA…”
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Abstract TP109: The Impact Of Atrial Fibrillation (Afib) On The Discharge Disposition In Patients Who Received Acute Stroke Intervention Therapies? Results From A Large Health System In Six Western States Of The United States
Published in Stroke (1970) (01-02-2023)“…IntroductionLimited studies indicate patients with acute ischemic stroke (AIS) due to atrial fibrillation (Afib) may not respond as well to intravenous…”
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Abstract TP14: Does Atrial Fibrillation (Afib) Impact The Rate Of 90 Days Modified Rankin Scale (mRS) In Patients Who Received Intravenous Thrombolytic (IVT) Before Endovascular Treatment (EVT)?results From A Large Health System In Six Western States Of The United States
Published in Stroke (1970) (01-02-2023)“…IntroductionPrevious studies indicate patients with acute ischemic stroke (AIS) due to Afib may not respond well to intravenous thrombolysis (IVT) compared to…”
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Abstract WP161: Does History Of Atrial Fibrillation (Afib) Impact TICI Scores In Acute Ischemic Stroke Patients Receiving Endovascular Treatment With Or Without Iv Thrombolytics? Results From A Large Health System In Six Western States Of The United States
Published in Stroke (1970) (01-02-2023)“…IntroductionDespite the importance of Afib in stroke, it is unclear whether patients with acute ischemic stroke (AIS) and Afib have a different response to…”
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Abstract P5: IV Alteplase Benefits Thrombectomy Patients With Incomplete TICI 2 Endovascular Reperfusion but Not Those With Complete TICI 3 Endovascular Reperfusion
Published in Stroke (1970) (01-03-2021)“…IntroductionThere is debate regarding how IV tPA influences the efficacy of Endovascular therapy (EVT). One hypothesized potential benefit of thrombolytics is…”
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Abstract P8: IV Alteplase Prior to Thrombectomy Benefitted Patients With M1 Occlusions but Not Thrombectomy Patients With M2 Occlusions
Published in Stroke (1970) (01-03-2021)“…IntroductionEndovascular Therapy (EVT) has overwhelming efficacy for the treatment of acute ischemic stroke due to large vessel occlusion. There is debate…”
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Abstract P122: The Impact of Center Certification Status on Acute Stroke Care Within a Multi-Hospital System in Western United States
Published in Stroke (1970) (01-03-2021)“…IntroductionWe aimed to investigate the impact of certification status on process of care metrics and clinical outcome in a large multi-center hospital system…”
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Abstract WP120: Can Early Transcranial Doppler Ultrasound Predict Early Neurological Deterioration And Risk Of Hemorrhagic Transformation After Endovascular Treatment?
Published in Stroke (1970) (01-02-2022)“…BackgroundRecent advances in endovascular therapy (EVT) have led to a significant improvement in functional outcomes of patients with stroke. However, early…”
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