Search Results - "Tarnuzzer, Roy"

Vacancy Engineered Ceria Nanostructures for Protection from Radiation-Induced Cellular Damage by Tarnuzzer, Roy W, Colon, Jimmie, Patil, Swanand, Seal, Sudipta

“…The ability of engineered cerium oxide nanoparticles to confer radioprotection was examined. Human normal and tumor cells were treated with nanoceria and…”
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Integrated Molecular Characterization of Uterine Carcinosarcoma by Cherniack, Andrew D., Murray, Bradley A., Hu, Xin, Ling, Shiyun, Soslow, Robert A., Zuna, Rosemary E., Laird, Peter W., Kucherlapati, Raju, Mills, Gordon B., Akbani, Rehan, Auman, J. Todd, Balasundaram, Miruna, Balu, Saianand, Baylin, Stephen B., Bodenheimer, Tom, Bogomolniy, Faina, Brooks, Denise, Carlsen, Rebecca, Cherniack, Andrew D., Cho, Juok, Chuah, Eric, Chudamani, Sudha, David, Mutch, Ferguson, Martin L., Frick, Jessica, Gabriel, Stacey, Gehlenborg, Nils, Gerken, Mark, Getz, Gad, Gupta, Manaswi, Heiman, David I., Hess, Julian, Hoffmann, Robert, Holt, Robert A., Hu, Xin, Hutter, Carolyn M., Jefferys, Stuart R., Kanchi, Rupa S., Kandoth, Cyriac, Kerr, Sarah, Kim, Jaegil, Lai, Phillip H., Laird, Peter W., Lander, Eric, Lawrence, Michael S., Lee, Darlene, Leshchiner, Ignaty, Levine, Douglas A., Lichtenberg, Tara M., Ling, Shiyun, Liu, Jia, Liu, Wenbin, Lolla, Laxmi, Lu, Yiling, Ma, Yussanne, Maglinte, Dennis T., Marra, Marco A., Mayo, Michael, Meng, Shaowu, Meyerson, Matthew, Moore, Richard A., Mose, Lisle E., Mungall, Karen, Murray, Bradley A., Naresh, Rashi, Parker, Joel S., Perou, Charles M., Radenbaugh, Amie J., Ramirez, Nilsa C., Rathmell, W. Kimryn, Roach, Jeffrey, Robertson, A. Gordon, Sadeghi, Sara, Saksena, Gordon, Salvesen, Helga B., Sheth, Margi, Shi, Yan, Shih, Juliann, Skelly, Tara, Sofia, Heidi J., Soloway, Matthew G., Sun, Charlie, Tan, Donghui, Tarnuzzer, Roy, Thorne, Leigh B., Tseng, Jill, Veluvolu, Umadevi, Verhaak, Roel G.W., Voet, Doug, Wan, Yunhu, Wang, Chen, Weisenberger, Daniel J., Wilkerson, Matthew D., Winterhoff, Boris, Wong, Tina, Yang, Liming, Zhang, Hailei, Zhu, Jing-chun, Zuna, Rosemary E., Weinstein, John N.

“…We performed genomic, epigenomic, transcriptomic, and proteomic characterizations of uterine carcinosarcomas (UCSs). Cohort samples had extensive copy-number…”
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Estrogen accelerates cutaneous wound healing associated with an increase in TGF-β1 levels by Ashcroft, Gillian S, Dodsworth, Joanne, Boxtel, Egon Van, Tarnuzzer, Roy W, Horan, Michael A, Schultz, Gregory S, Ferguson, Mark W.J

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Analysis of germline-driven ancestry-associated gene expression in cancers by Chambwe, Nyasha, Sayaman, Rosalyn W., Hu, Donglei, Huntsman, Scott, Carrot-Zhang, Jian, Berger, Ashton C., Han, Seunghun, Meyerson, Matthew, Damrauer, Jeffrey S., Hoadley, Katherine A., Felau, Ina, Demchok, John A., Mensah, Michael K.A., Tarnuzzer, Roy, Wang, Zhining, Yang, Liming, Knijnenburg, Theo A., Robertson, A. Gordon, Yau, Christina, Benz, Christopher, Huang, Kuan-lin, Newberg, Justin Y., Frampton, Garrett M., Mashl, R. Jay, Ding, Li, Romanel, Alessandro, Demichelis, Francesca, Zhou, Wanding, Laird, Peter W., Shen, Hui, Wong, Christopher K., Stuart, Joshua M., Lazar, Alexander J., Le, Xiuning, Oak, Ninad, Kemal, Anab, Caesar-Johnson, Samantha, Zenklusen, Jean C., Ziv, Elad, Beroukhim, Rameen, Cherniack, Andrew D.

“…Differential mRNA expression between ancestry groups can be explained by both genetic and environmental factors. We outline a computational workflow to…”
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Analytical protocol to identify local ancestry-associated molecular features in cancer by Carrot-Zhang, Jian, Han, Seunghun, Zhou, Wanding, Damrauer, Jeffrey S., Kemal, Anab, Berger, Ashton C., Meyerson, Matthew, Hoadley, Katherine A., Felau, Ina, Caesar-Johnson, Samantha, Demchok, John A., Mensah, Michael K.A., Tarnuzzer, Roy, Wang, Zhining, Yang, Liming, Zenklusen, Jean C., Chambwe, Nyasha, Knijnenburg, Theo A., Robertson, A. Gordon, Yau, Christina, Benz, Christopher, Huang, Kuan-lin, Newberg, Justin, Frampton, Garret, Mashl, R. Jay, Ding, Li, Romanel, Alessandro, Demichelis, Francesca, Sayaman, Rosalyn W., Ziv, Elad, Laird, Peter W., Shen, Hui, Wong, Christopher K., Stuart, Joshua M., Lazar, Alexander J., Le, Xiuning, Oak, Ninad, Cherniack, Andrew D., Beroukhim, Rameen

“…People of different ancestries vary in cancer risk and outcome, and their molecular differences may indicate sources of these variations. Determining the…”
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Matrix Metalloproteinase Inhibition Modulates Fibroblast-Mediated Matrix Contraction and Collagen Production In Vitro by Daniels, Julie T, Cambrey, Alison D, Occleston, Nicholas L, Garrett, Qian, Tarnuzzer, Roy W, Schultz, Gregory S, Khaw, Peng T

“…To investigate the effect of matrix metalloproteinase (MMP) inhibition on fibroblast-mediated matrix contraction and production. Free-floating…”
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Fibronectin fragments promote human retinal endothelial cell adhesion and proliferation and ERK activation through α5β1 Integrin and PI 3-kinase by WILSON, Sylvia H, LJUBILMOV, Alexander V, MORTAL, Alex O, CABALLERO, Sergio, SHAW, Lynn C, SPOERRI, Polyxenie E, TARNUZZER, Roy W, GRANT, Maria B

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Adenosine Receptor Activation Induces Vascular Endothelial Growth Factor in Human Retinal Endothelial Cells by Grant, Maria B, Tarnuzzer, Roy W, Caballero, Sergio, Ozeck, Mark J, Davis, Margaret I, Spoerri, Polyxenie E, Feoktistov, Igor, Biaggioni, Italo, Shryock, John C, Belardinelli, Luiz

“…Adenosine, released in increased amounts by hypoxic tissues, is thought to be an angiogenic factor that links altered cellular metabolism caused by oxygen…”
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Effects of Tenascin-C on Normal and Diabetic Retinal Endothelial Cells in Culture by Castellon, Raquel, Caballero, Sergio, Hamdi, Hamdi K, Atilano, Shari R, Aoki, Annette M, Tarnuzzer, Roy W, Kenney, M. Cristina, Grant, Maria B, Ljubimov, Alexander V

“…Tenascin-C (TN-C) is expressed in embryogenesis, tissue remodeling, and healing. It is up-regulated in retinas of patients affected by diabetic retinopathy…”
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Comprehensive Characterization of Cancer Driver Genes and Mutations by Colaprico, Antonio, Cao, Song, Liang, Wen-Wei, Hess, Julian M., Ferguson, Martin L., Hutter, Carolyn M., Tarnuzzer, Roy, Wang, Zhining, Noble, Michael S., Dhankani, Varsha, Knijnenburg, Theo, Miller, Michael, Abeshouse, Adam, Ladanyi, Marc, Luna, Augustin, Wong, Christopher K., Yau, Christina, Kasaian, Katayoon, Kucherlapati, Melanie H., Danilova, Ludmila, Bootwalla, Moiz S., Fan, Cheng, Mose, Lisle E., Roach, Jeffrey, Tan, Donghui, Covington, Kyle, Donehower, Lawrence A., Drummond, Jennifer, Liu, Xiuping, Morgan, Margaret, Wheeler, David A., Appelbaum, Elizabeth L., Bailey, Matthew, Kandoth, Cyriac, Wilson, Richard K., Penny, Robert, Thompson, Eric, Zmuda, Erik, de Carvalho, Ana C., Fregnani, José H., Huntsman, David, Kohl, Bernard, Paklina, Oxana, McPherson, Christopher, Barnholtz-Sloan, Jill S., Tucker, Kelinda, Larson, Caroline, Iacocca, Mary, Bergeron, Alain, Sepulveda, Antonia, Desjardins, Laurence, Sastre, Xavier, Cheng, Feixiong, Force, Seth, Khuri, Fadlo, Owonikoko, Taofeek, Korpershoek, Esther, Looijenga, Leendert, DiMeco, Francesco, Kycler, Witold, Chung, Ki, Noushmehr, Houtan, Scarpace, Lisa, Campo, Elias, Van Bang, Nguyen, Colman, Howard, Breggia, Anne, Bryce, Alan H., Copland, John A., Petersen, Gloria, Zhang, Lizhi, Mann, Graham, Mirsaidi, Cyrus, Zaren, Howard, Stancul, Irina, Tcaciuc, Diana, Arnaout, Angel, Rassl, Doris M., Urba, Walter, Farver, Carol, Raymond, Daniel, Dinkin, Mikhail, Carpino, Guido, Dubina, Michael, Abdel-Rahman, Mohamed H., Mandt, Randy, Nguyen, Phuong, Rai, Karan, Waldmann, Jens, Fassnacht, Martin, Simon, Ronald, Fehrenbach, Ashley, von Deimling, Andreas, Jacobus, Laura, Carlotti, Carlos Gilberto, Godwin, Eryn M., Carey, Thomas, Getz, Gad, Lazar, Alexander J., Ding, Li

“…Identifying molecular cancer drivers is critical for precision oncology. Multiple advanced algorithms to identify drivers now exist, but systematic attempts to…”
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The repertoire of mutational signatures in human cancer by Alexandrov, Ludmil B., Kim, Jaegil, Haradhvala, Nicholas J., Huang, Mi Ni, Tian Ng, Alvin Wei, Wu, Yang, Boot, Arnoud, Covington, Kyle R., Gordenin, Dmitry A., Bergstrom, Erik N., Islam, S. M. Ashiqul, Lopez-Bigas, Nuria, Klimczak, Leszek J., McPherson, John R., Morganella, Sandro, Sabarinathan, Radhakrishnan, Wheeler, David A., Mustonen, Ville, Getz, Gad, Rozen, Steven G., Stratton, Michael R.

“…Somatic mutations in cancer genomes are caused by multiple mutational processes, each of which generates a characteristic mutational signature 1 . Here, as…”
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Pan-cancer analysis of whole genomes by Campbell, Peter J, Getz, Gad, Korbel, Jan O, Stuart, Joshua M, Jennings, Jennifer L, Stein, Lincoln D, Perry, Marc D

“…Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome…”
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Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer by Kim, Jaegil, Bellmunt, Joaquim, Cherniack, Andrew D., Hinoue, Toshinori, Hoadley, Katherine A., Gibb, Ewan A., Shukla, Sachet A., Sanchez-Vega, Francisco, Reuter, Victor E., Sadeghi, Sara, Pedamallu, Chandra Sekhar, Lu, Yiling, Klimczak, Leszek J., Zhang, Jiexin, Choo, Caleb, Leraas, Kristen M., Lichtenberg, Tara M., Schultz, Nicholaus, Getz, Gad, Mills, Gordon B., Al-Ahmadie, Hikmat, Alexopoulou, Iakovina, Ally, Adrian, Beaver, Allison, Bellmunt, Joaquim, Boice, Lori, Bootwalla, Moiz S., Bowen, Jay, Brooks, Denise, Broom, Bradley M., Bshara, Wiam, Bullman, Susan, Burks, Eric, Carvalho, Benilton S., Carvalho, Andre L., Castro, Mauro A.A., Chagas, Vinicius S., Cherniack, Andrew D., Cortessis, Victoria K., Czerniak, Bogdan A., Daneshmand, Siamak, Dhalla, Noreen, Egea, Sophie C., Engel, Jay, Felau, Ina, Gastier-Foster, Julie M., Getz, Gad, Gordenin, Dmitry A., Hansel, Donna E., Harr, Jodi, Hartmann, Arndt, Hinoue, Toshinori, Jones, Steven J.M., Kahnoski, Richard J., Kasaian, Katayoon, Lai, Phillip H., Lane, Brian R., Liu, Jia, Lolla, Laxmi, Lotan, Yair, Lu, Yiling, Lucchesi, Fabiano R., Mallery, David, Marra, Marco A., Mills, Gordon B., Mungall, Karen L., Ojesina, Akinyemi I., Parekh, Dipen J., Sekhar Pedamallu, Chandra, Pihl, Todd, Rathmell, W. Kimryn, Robertson, A. Gordon, Sadeghi, Sara, Saller, Charles, Salner, Andrew, Sanchez-Vega, Francisco, Scapulatempo-Neto, Cristovam, Schuckman, Anne K., Shukla, Sachet A., Simko, Jeff, Sipahimalani, Payal, Sorcini, Andrea, Stoehr, Robert, Su, Xiaoping, Tarnuzzer, Roy, Thiessen, Nina, Thorne, Leigh, Tse, Kane, Wach, Sven, Wang, Zhining, Weinstein, John N., Wise, Lisa, Wong, Tina, Wu, Ye, Zach, Leigh Anne, Zenklusen, Jean C., Zhang, Jiashan (Julia), Zhang, Jiexin, Zwarthoff, Ellen C., Weinstein, John N.

“…We report a comprehensive analysis of 412 muscle-invasive bladder cancers characterized by multiple TCGA analytical platforms. Fifty-eight genes were…”
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Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma by Carlsen, Rebecca, Chuah, Eric, Clarke, Amanda, Holt, Robert A., Mayo, Michael, Schein, Jacqueline E., Thiessen, Nina, Cheung, Dorothy, Bowlby, Reanne, Shinbrot, Eve, Donehower, Lawrence A., Bowen, Jay, Helsel, Carmen, Leraas, Kristen M., Wise, Lisa, Shih, Juliann, Cherniack, Andrew D., Saksena, Gordon, Pedamallu, Chandra Sekhar, Chin, Lynda, Cho, Juok, Defreitas, Timothy, Meier, Sam, Lawrence, Michael, Hu, Jianhong, Wang, Min, Morton, Donna, Korchina, Viktoriya, Lewis, Lora, Bellair, Michelle, Lee, Sandra, Shmulevich, Ilya, Zhang, Wei, Liu, Yuexin, Iype, Lisa, Makhlouf, Hala, Kakar, Sanjay, Yeh, Matthew M., Kleiner, David E., El-Serag, Hashem B., Mishra, Lopa, Ling, Shiyun, Su, Xiaoping, Chen, Jian, Tong, Pan, Aburatani, Hiroyuki, Tatsuno, Kenji, Seiser, Eric, Gao, Jianjiong, Ochoa, Angelica, Shen, Ronglai, Arora, Arshi, Radenbaugh, Amie, Moore, David D., Totoki, Yasushi, Shibata, Tatsuhiro, Yau, Christina, Slagle, Betty L., Ojesina, Akinyemi I., Koire, Amanda, Hsu, Teng-Kuei, Felau, Ina, Wang, Zhining, Yang, Liming, Zenklusen, Jean C., Hutter, Carolyn M., Sofia, Heidi J., Chudamani, Sudha, Liu, Jia, Lolla, Laxmi, Wu, Ye, Pihl, Todd, Huang, Mei, Junior, Carlos Gilberto Carlotti, Silva, Orlando de Castro, Ahn, Keun Soo, Moser, Catherine D., Giordano, Thomas J., Crain, Daniel, Curley, Erin, Morris, Scott, Paulauskis, Joseph, Shelton, Candace, Shelton, Troy, Roberts, Lewis R., Hagedorn, Curt H., O'Brien, Daniel R., Perou, Charles M., Skelly, Tara, Veluvolu, Umadevi, Balu, Saianand, Hoyle, Alan P., Jefferys, Stuart R., Meng, Shaowu, Mose, Lisle E., Simons, Janae V., Hoadley, Katherine A., Shen, Hui, Berrios, Mario, Laird, Peter W.

“…Liver cancer has the second highest worldwide cancer mortality rate and has limited therapeutic options. We analyzed 363 hepatocellular carcinoma (HCC) cases…”
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Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma by Hruban, Ralph H., Moffitt, Richard A., Gupta, Manaswi, Getz, Gad, Gabriel, Stacey B., Meyerson, Matthew, Laird, Peter W., Loher, Phillipe, Rigoutsos, Isidore, Telonis, Aristeidis G., Mezlini, Aziz M., Hoadley, Katherine A., Murray, Bradley A., Hess, Julian, Zhang, Hailei, Tiao, Grace, Schumacher, Steven E., Noble, Michael S., Gehlenborg, Nils, Lawrence, Michael S., Bowlby, Reanne, Birol, Inanc, Weinstein, John N., Spellman, Paul T., Liu, Yuexin, Paul, Drwiega, Smyrk, Thomas, Gerken, Mark, Lau, Kevin, Renkel, Jeremy, Wise, Lisa, Yena, Peggy, Zmuda, Erik, Shih, Juliann, Balasundaram, Miruna, Chu, Andy, Chuah, Eric, Dhalla, Noreen, Mungall, Andrew J., Thiessen, Nina, Brooks, Denise, Balu, Saianand, Jefferys, Stuart R., Jones, Corbin D., Mose, Lisle E., Shi, Yan, Simons, Janae V., Soloway, Matthew G., Tan, Donghui, Chaffee, Kari, Oberg, Ann, Wheeler, David A., Bartlett, John, Stephen, Yeager, Howard, Zaren, Breggia, Anne, Shroff, Rachna T., Liu, Jia, Lolla, Laxmi, Pihl, Todd, Roggin, Kevin, Becker, Karl-Friedrich, Boice, Lori, Pretti da Cunha Tirapelli, Daniela, Huelsenbeck-Dill, Lori, Jenkins, Roger, Kemp, Rafael, Lyadov, Vladimir, Maithel, Shishir, Manikhas, Georgy, Montgomery, Eric, Noushmehr, Houtan, Owonikoko, Taofeek, Rieger-Christ, Kimberly, Sica, Gabriel, Su, Tao, Sullivan, Travis, Tarvin, Katherine, Urbanski, Stefan, Curley, Erin, Gardner, Johanna, Shelton, Candace, Bathe, Oliver, Hibshoosh, Hanina, Radenbaugh, Amie, Berrios, Mario, Bootwalla, Moiz S., Maglinte, Dennis T., Triche, Timothy J., Weisenberger, Daniel J., Kucherlapati, Melanie, Meier, Sam, Tempero, Margaret, Bailey, Peter, Gill, Anthony, Kench, James, Demchok, John A., Ferguson, Martin L., Tarnuzzer, Roy, Wang, Zhining

“…We performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic ductal adenocarcinoma (PDAC) specimens, including samples with…”
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Integrated genomic characterization of oesophageal carcinoma by Reis, R. M., The Cancer Genome Atlas Research Network

“…This work was supported by the Intramural Research Program and the following grants from the United States National Institutes of Health: 5U24CA143799,…”
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Integrated genomic and molecular characterization of cervical cancer by Saller, Charles, Tarvin, Katherine, Yau, Christina, Robertson, A. Gordon, Mungall, Karen, Lim, Lynette, Mar, Richard, Clarke, Amanda, Tam, Angela, Dhalla, Noreen, Carlsen, Rebecca, Holt, Robert A, Jones, Steven J. M, Hadjipanayis, Angela, Seidman, Jonathan, Rabeno, Brenda, Huelsenbeck-Dill, Lori, Iacocca, Mary, Petrelli, Nicholas, Adebamowo, Sally N, Adebamowo, Clement, Shelton, Candace, Crain, Daniel, Mallery, David, Curley, Erin, Gardner, Johanna, Shelton, Troy, Wu, Ye, Birrer, Michael, Miller, Christopher A, Fulton, Robert S, Appelbaum, Elizabeth L, Rader, Janet S, Behmaram, Behnaz, Bradley, William, Wrangle, John, Schultz, Nikolaus, Ladanyi, Marc, Felau, Ina, Zenklusen, Jean C, Demchok, John A, Sheth, Margi, Ferguson, Martin L, Tarnuzzer, Roy, Zhang, Jiashan, Wang, Zhining, Olaniyan, Olayinka, Sofia, Heidi J, Chen, Zhong, Saleh, Anthony D, Cheng, Hui, Parfitt, Jeremy, Albert, Monique, Sekhon, Harman, Gilbert, Sebastien, Myers, Jerome, Tucker, Kelinda, Lester, Jenny, Wan, Yunhu, Miller, Judy, Cherniack, Andrew D, Meyerson, Matthew, Voet, Doug, Kim, Jaegil, Lawrence, Michael S, Gehlenborg, Nils, Lin, Pei, Gabriel, Stacey B, Schumacher, Steven E, Leraas, Kristen M, Gastier-Foster, Julie M, Danilova, Ludmila, Salvesen, Helga B, Ju, Zhenlin, Diao, Lixia, Zhao, Hao, Ryan, Michael C, Averett Byers, Lauren, Yuan, Yuan, Bristow, Christopher A, Shaw, Kenna R. Mills, Radenbaugh, Amie, Chalise, Prabhakar, Godwin, Andrew K, Auman, J. Todd, Perou, Charles M, Veluvolu, Umadevi, Rathmell, W. Kimryn, Simons, Janae V, Mose, Lisle E, Shi, Yan, Thorne, Leigh B, Walker, Joan, Moore, Kathleen, McMeekin, Scott, Nelson, Tina, Bhargava, Rohit, Bootwalla, Moiz S, Triche, Timothy, Jr, Agnew, Kathy J

“…Cervical cancer remains one of the leading causes of cancer-related deaths worldwide. Here we report the extensive molecular characterization of 228 primary…”
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Pathogenic Germline Variants in 10,389 Adult Cancers by Ritter, Deborah I., Reynolds, Sheila, Houlahan, Kathleen E., Cho, Juok, Reynolds, Sheila, Akbani, Rehan, Phillips, Sarah M., Zhang, Hongxin, Balasundaram, Miruna, Chuah, Eric, Holt, Robert, Schein, Jacqueline E., Sipahimalani, Payal, Thiessen, Nina, Beroukhim, Rameen, Cope, Leslie, Weisenberger, Daniel J., Hoyle, Alan P., Jefferys, Stuart R., Mieczkowski, Piotr A., Perou, Amy H., Shi, Yan, Veluvolu, Umadevi, Fan, Huihui, Donehower, Lawrence A., Ding, Li, Mardis, Elaine R., Curley, Erin, Mallery, David, Paulauskis, Joseph, Lichtenberg, Tara M., Eschbacher, Jennifer, Ittmann, Michael, Andry, Chris, Tavobilov, Mikhail, Cramer, Daniel, Barrett, Wendi, Karlan, Beth Y., Zach, Leigh Anne, Hu, Hai, Swanson, Patricia, Chabot, John, Su, Tao, Voronina, Olga, Signoretti, Sabina, Berchuck, Andrew, Houck, John, Hartmann, Arndt, Hanh, Phan Thi, Juhl, Hartmut, Kopp, Karla, Roberts, Lewis, Yang, Ju Dong, Moran, Cesar, Ramondetta, Lois, Troncoso, Patricia, Tsao, Anne, Wistuba, Ignacio, Scolyer, Richard, Stretch, Jonathan, Wilmott, James, Reuter, Victor, Park, Joong-Won, Hung, Nguyen Phi, Kebebew, Electron, Pinto, Peter A., Moncrieff, Marc, Pass, Harvey, Botnariuc, Natalia, Pirtac, Maria, Tamakawa, Raina, Antenucci, Anna, Facciolo, Francesco, Chevalier, Simone, Brewer, Cathy, Pennell, Nathan A., Omberg, Larsson, Pilarski, Robert, Senecal, Kelly, Schadendorf, Dirk, Sauter, Guido, Olabode, Oluwole, Disaia, Philip, Roggin, Kevin, Mannelli, Massimo, Postier, Russel, Walker, Joan, Feldman, Michael, Dhir, Rajiv, Luketich, James, Prince, Mark, Rozek, Laura, Fong, Kwun M., Shriver, Craig D., Govindan, Ramaswamy, Heath, Sharon, Aredes, Natália D., Wendl, Michael C., Reimand, Jüri, Meric-Bernstam, Funda

“…We conducted the largest investigation of predisposition variants in cancer to date, discovering 853 pathogenic or likely pathogenic variants in 8% of 10,389…”
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The evolutionary history of 2,658 cancers by Gerstung, Moritz, Jolly, Clemency, Leshchiner, Ignaty, Dentro, Stefan C., Gonzalez, Santiago, Rosebrock, Daniel, Mitchell, Thomas J., Rubanova, Yulia, Anur, Pavana, Yu, Kaixian, Tarabichi, Maxime, Deshwar, Amit, Wintersinger, Jeff, Kleinheinz, Kortine, Vázquez-García, Ignacio, Haase, Kerstin, Jerman, Lara, Sengupta, Subhajit, Macintyre, Geoff, Malikic, Salem, Donmez, Nilgun, Livitz, Dimitri G., Cmero, Marek, Demeulemeester, Jonas, Schumacher, Steven, Fan, Yu, Yao, Xiaotong, Lee, Juhee, Schlesner, Matthias, Boutros, Paul C., Bowtell, David D., Zhu, Hongtu, Getz, Gad, Imielinski, Marcin, Beroukhim, Rameen, Sahinalp, S. Cenk, Ji, Yuan, Peifer, Martin, Markowetz, Florian, Mustonen, Ville, Yuan, Ke, Wang, Wenyi, Morris, Quaid D., Spellman, Paul T., Wedge, David C., Van Loo, Peter

“…Cancer develops through a process of somatic evolution 1 , 2 . Sequencing data from a single biopsy represent a snapshot of this process that can reveal the…”
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The Molecular Taxonomy of Primary Prostate Cancer by Abeshouse, Adam, Akbani, Rehan, Ally, Adrian, Andry, Christopher D., Auman, J. Todd, Beroukhim, Rameen, Boutros, Paul C., Bradley, Robert K., Bristow, Christopher A., Bryce, Alan H., Butterfield, Yaron S.N., Button, Michael, Carroll, Peter R., Carter, Scott L., Carver, Brett S., Chan, June M., Chen, Yu, Cherniack, Andrew D., Cibulskis, Kristian, Ciriello, Giovanni, Costello, Anthony J., Dvinge, Heidi, Felau, Ina, Gardner, Johanna, Gehlenborg, Nils, Graefen, Markus, Guin, Ranabir, Gupta, Manaswi, Hadjipanayis, Angela, Hayes, D. Neil, Heiman, David I., Hoadley, Katherine A., Holbrook, Andrea H., Hoyle, Alan P., Huang, Mei, Ittmann, Michael, Kahles, Andre, Kane, Christopher J., Kerger, Michael, Klein, Robert J., Lai, Phillip H., Laird, Peter W., Lander, Eric S., Latour, Mathieu, Lawrence, Michael S., Lau, Kevin, LeBien, Tucker, Leraas, Kristen M., Lin, Pei, Linehan, W. Marston, Lolla, Laxmi, Longacre, Teri, Lu, Yiling, Mallery, David, Mariamidze, Armaz, Meng, Shaowu, Meyerson, Matthew, Mieczkowski, Piotr A., Mills, Gordon B., Minner, Sarah, Morrison, Carl, Naresh, Rashi, Nelson, Joel, Nelson, Peter S., Newton, Yulia, Noushmehr, Houtan, Parfenov, Michael, Park, Peter J., Piché, Alain, Rathmell, W. Kimryn, Reynolds, Sheila M., Roach, Jeffrey, Robertson, A. Gordon, Sadeghi, Sara, Scarlata, Eleonora, Shen, Ronglai, Shi, Yan, Shih, Juliann, Skelly, Tara, Sofia, Heidi J., Stewart, Chip, Sun, Charlie, Tan, Donghui, Taylor, Barry S., Teebagy, Patrick, Têtu, Bernard, Thiessen, Nina, Tirapelli, Daniela P., Tomlins, Scott A., Trevisan, Felipe Amstalden, True, Lawrence D., Weinhold, Nils, Wilkerson, Matthew D., Wu, Junyuan, Wu, Ye, Xu, Andrew W., Yadav, Shalini S., Yang, Lixing, Yena, Peggy, Zeng, Thomas

“…There is substantial heterogeneity among primary prostate cancers, evident in the spectrum of molecular abnormalities and its variable clinical course. As part…”
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