Search Results - "Tarnow, L"
-
1
Vitamin D analogue therapy, cardiovascular risk and kidney function in people with Type 1 diabetes mellitus and diabetic nephropathy: a randomized trial
Published in Diabetic medicine (01-03-2015)“…Aim To evaluate the effects of therapy with the vitamin D analogue paricalcitol on markers of cardiovascular risk and kidney function in people with Type 1…”
Get full text
Journal Article -
2
Plasma matrix metalloproteinases are associated with incident cardiovascular disease and all-cause mortality in patients with type 1 diabetes: a 12-year follow-up study
Published in Cardiovascular diabetology (26-04-2017)“…Altered regulation of extracellular matrix remodeling by matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) may contribute to…”
Get full text
Journal Article -
3
Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy
Published in Kidney international (01-08-2006)“…Reduction of nephrotic range albuminuria is associated with markedly improved renal and cardiovascular outcome in patients with diabetic nephropathy…”
Get full text
Journal Article -
4
At least one in three people with Type 2 diabetes mellitus referred to a diabetes centre has symptomatic obstructive sleep apnoea
Published in Diabetic medicine (01-11-2014)“…Aims To investigate the prevalence of symptomatic obstructive sleep apnoea in unselected patients with Type 2 diabetes referred to a tertiary diabetes clinic…”
Get full text
Journal Article -
5
Effect of metformin and insulin vs. placebo and insulin on whole body composition in overweight patients with type 2 diabetes: a randomized placebo-controlled trial
Published in Osteoporosis international (01-09-2021)“…Summary Some studies indicate potential beneficial effects of metformin on body composition and bone. This trial compared metformin + insulin vs placebo +…”
Get full text
Journal Article -
6
Time course of the antiproteinuric and antihypertensive effects of direct renin inhibition in type 2 diabetes
Published in Kidney international (01-06-2008)“…Inhibition of renin with an active site inhibitor, aliskiren, lowers blood pressure (BP) in diabetic patients. Here, we studied the time course of the…”
Get full text
Journal Article -
7
The effect of metformin versus placebo in combination with insulin analogues on bone mineral density and trabecular bone score in patients with type 2 diabetes mellitus: a randomized placebo-controlled trial
Published in Osteoporosis international (01-11-2018)“…Summary Some antihyperglycemic medications have been found to affect bone metabolism. We assessed the long-term effects of metformin compared with placebo on…”
Get full text
Journal Article -
8
Arterial stiffness in people with Type 2 diabetes and obstructive sleep apnoea
Published in Diabetic medicine (01-10-2018)“…Aims To examine whether people with Type 2 diabetes with concurrent obstructive sleep apnoea have increased arterial stiffness as compared with people with…”
Get full text
Journal Article -
9
Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Kidney Injury Molecule 1 (KIM1) in patients with diabetic nephropathy: a cross-sectional study and the effects of lisinopril
Published in Diabetic medicine (01-10-2010)“…Diabet. Med. 27, 1144–1150 (2010) Aims Our aim was to evaluate the markers of tubulointerstitial damage, neutrophil gelatinase‐associated lipocalin (NGAL) and…”
Get full text
Journal Article -
10
A phase 2a, randomized, double‐blind 28‐day study of TZP‐102 a ghrelin receptor agonist for diabetic gastroparesis
Published in Neurogastroenterology and motility (01-02-2013)“…Background Gastroparesis causes significant morbidity and treatment options are limited. TZP‐102 a novel, macrocyclic, selective, oral ghrelin receptor…”
Get full text
Journal Article -
11
-
12
Increased serum adiponectin levels in type 1 diabetic patients with microvascular complications
Published in Diabetologia (01-09-2005)“…Low serum adiponectin (ADPN) has been associated with increased risk of cardiovascular disease (CVD) and retinopathy in patients with type 2 diabetes mellitus…”
Get full text
Journal Article -
13
Plasma N-terminal pro-B-type natriuretic peptide and mortality in type 2 diabetes
Published in Diabetologia (01-10-2006)“…Aims/hypothesis Raised N-terminal pro-B-type natriuretic peptide (NT-proBNP) is associated with a poor cardiac outcome in non-diabetic populations. Elevated…”
Get full text
Journal Article -
14
QT interval prolongation during spontaneous episodes of hypoglycaemia in type 1 diabetes: the impact of heart rate correction
Published in Diabetologia (01-09-2010)“…Aims/hypothesis Prolongation of the heart rate corrected QT interval (QTc) is seen during episodes of hypoglycaemia in type 1 diabetes. We studied the…”
Get full text
Journal Article -
15
Comparing effects of insulin analogues and human insulin on nocturnal glycaemia in hypoglycaemia‐prone people with Type 1 diabetes
Published in Diabetic medicine (01-05-2017)“…Aims To assess the difference between analogue and human insulin with regard to nocturnal glucose profiles and risk of hypoglycaemia in people with recurrent…”
Get full text
Journal Article -
16
Arterial stiffness and endothelial dysfunction independently and synergistically predict cardiovascular and renal outcome in patients with type 1 diabetes
Published in Diabetic medicine (01-08-2012)“…Diabet. Med. 29, 990–994 (2012) Aims To evaluate whether pulse pressure alone or with placental growth factor as estimates of arterial stiffness and…”
Get full text
Journal Article -
17
Telomere length predicts all-cause mortality in patients with type 1 diabetes
Published in Diabetologia (2010)“…Aims/hypothesis Type 1 diabetic patients with diabetic nephropathy have increased mortality and morbidity compared with normoalbuminuric patients. Telomere…”
Get full text
Journal Article -
18
Effect of insulin analogues on frequency of non-severe hypoglycaemia in patients with type 1 diabetes prone to severe hypoglycaemia: The HypoAna trial
Published in Diabetes & metabolism (01-09-2016)“…Abstract Aim Insulin analogues reduce the risk of hypoglycaemia compared with human insulin in patients with type 1 diabetes (T1D) and minor hypoglycaemia…”
Get full text
Journal Article -
19
Hypoglycaemia and QT interval prolongation in type 1 diabetes – bridging the gap between clamp studies and spontaneous episodes
Published in Journal of diabetes and its complications (01-09-2014)“…Abstract Aims We propose a study design with controlled hypoglycaemia induced by subcutaneous injection of insulin and matched control episodes to bridge the…”
Get full text
Journal Article -
20
Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate
Published in Diabetologia (01-11-2004)“…It has been suggested that aldosterone plays a role in the initiation and progression of renal disease independently of arterial blood pressure and plasma…”
Get full text
Journal Article