Search Results - "Tarn, Derrick"
-
1
Use of Size and a Copolymer Design Feature To Improve the Biodistribution and the Enhanced Permeability and Retention Effect of Doxorubicin-Loaded Mesoporous Silica Nanoparticles in a Murine Xenograft Tumor Model
Published in ACS nano (24-05-2011)“…A key challenge for improving the efficacy of passive drug delivery to tumor sites by a nanocarrier is to limit reticuloendothelial system uptake and to…”
Get full text
Journal Article -
2
Processing Pathway Dependence of Amorphous Silica Nanoparticle Toxicity: Colloidal vs Pyrolytic
Published in Journal of the American Chemical Society (26-09-2012)“…We have developed structure/toxicity relationships for amorphous silica nanoparticles (NPs) synthesized through low-temperature colloidal (e.g., Stöber…”
Get full text
Journal Article -
3
Involvement of Lysosomal Exocytosis in the Excretion of Mesoporous Silica Nanoparticles and Enhancement of the Drug Delivery Effect by Exocytosis Inhibition
Published in Small (Weinheim an der Bergstrasse, Germany) (11-03-2013)“…The exocytosis of phosphonate modified mesoporous silica nanoparticles (P‐MSNs) is demonstrated and lysosomal exocytosis is identified as the mechanism…”
Get full text
Journal Article -
4
Mesoporous Silica Nanoparticle Nanocarriers: Biofunctionality and Biocompatibility
Published in Accounts of chemical research (19-03-2013)“…The study of ordered mesoporous silica materials has exploded since their discovery by Mobil researchers 20 years ago. The ability to make uniformly sized,…”
Get full text
Journal Article -
5
pH-Responsive Dual Cargo Delivery from Mesoporous Silica Nanoparticles with a Metal-Latched Nanogate
Published in Inorganic chemistry (18-02-2013)“…A nanogate composed of two iminodiacetic acid (IDA) molecules and a metal ion latch was designed, synthesized, and assembled on mesoporous silica…”
Get full text
Journal Article -
6
Cardiac paraganglioma
Published in Canadian Medical Association journal (CMAJ) (31-07-2017)“…A 25-year-old woman with a history of anemia and anxiety presented to her hematologist with palpitations. An echocardiogram was ordered, which showed a right…”
Get full text
Journal Article -
7
Two-Photon-Triggered Drug Delivery via Fluorescent Nanovalves
Published in Small (Weinheim an der Bergstrasse, Germany) (14-05-2014)“…Mesoporous silica nanoparticles (MSN) are functionalized in the walls with an original fluorophore with a high two‐photon absorption cross‐section. The pores…”
Get full text
Journal Article -
8
Two-Photon-Triggered Drug Delivery in Cancer Cells Using Nanoimpellers
Published in Angewandte Chemie International Edition (16-12-2013)“…A therapy of cancer cells: Two‐photon‐triggered camptothecin delivery (see picture) with nanoimpellers was studied in MCF‐7 breast cancer cells. A fluorophore…”
Get full text
Journal Article -
9
Nanomachines on Porous Silica Nanoparticles for Cargo Delivery
Published 01-01-2013“…The field of nanomachines based on mesoporous and microporous silica nanoparticles is a relatively new one, but has quickly gained widespread popularity due to…”
Get full text
Dissertation -
10
Use of Size and a Co-polymer Design Feature to Improve the Biodistribution and the Enhanced Permeability and Retention Effect of Doxorubicin-loaded Mesoporous Silica Nanoparticles in a Murine Xenograft Tumor Model
Published in ACS nano (27-04-2011)“…A key challenge for improving the efficacy of passive drug delivery to tumor sites by a nanocarrier is to limit reticuloendothelial system (RES) uptake and to…”
Get full text
Journal Article -
11
Processing pathway dependence of amorphous silica nanoparticle toxicity - colloidal versus pyrolytic
Published in Journal of the American Chemical Society (17-09-2012)“…We have developed structure/toxicity relationships for amorphous silica nanoparticles (NPs) synthesized through low temperature, colloidal (e.g. Stöber silica)…”
Get full text
Journal Article -
12
Two-Photon-Triggered Drug Delivery in Cancer Cells Using Nanoimpellers
Published in Angewandte Chemie (16-12-2013)“…Transport per Flügelrad: Der durch einen Zweiphotonenprozess ausgelöste Camptothecin‐Transport in MCF‐7‐Krebszellen mithilfe von Nanoimpellern (siehe Bild)…”
Get full text
Journal Article -
13
Two‐Photon‐Triggered Drug Delivery in Cancer Cells Using Nanoimpellers
Published in Angewandte Chemie (16-12-2013)Get full text
Journal Article