Search Results - "Tariq, M."
-
1
Therapeutic targeting of microRNAs: current status and future challenges
Published in Nature reviews. Drug discovery (01-08-2014)“…Key Points MicroRNAs (miRNAs) have important roles in many aspects of human diseases, and their targeted inhibition may have substantial therapeutic impact…”
Get full text
Journal Article -
2
Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols
Published in Biomedicine & pharmacotherapy (01-09-2020)“…[Display omitted] •Here, we discussed the role of oxidative stress and inflammation in OA pathogenesis.•Here, we discussed the antioxidant and…”
Get full text
Journal Article -
3
Illuminating the silence: understanding the structure and function of small RNAs
Published in Nature reviews. Molecular cell biology (01-01-2007)“…RNA interference (RNAi) is triggered by double-stranded RNA helices that have been introduced exogenously into cells as small interfering (si)RNAs or that have…”
Get full text
Journal Article -
4
Post-Cataract Surgery Orbital Conjunctival Inclusion Cyst
Published in Ophthalmology (Rochester, Minn.) (01-09-2024)Get full text
Journal Article -
5
Morning Glory Disc Anomaly Associated Transsphenoidal Encephalocele
Published in Ophthalmology (Rochester, Minn.) (24-06-2024)Get full text
Journal Article -
6
Dehydrogenation of Alkanes and Aliphatic Groups by Pincer-Ligated Metal Complexes
Published in Chemical reviews (11-10-2017)“…The alkyl group is the most common component of organic molecules and the most difficult to selectively functionalize. The development of catalysts for…”
Get full text
Journal Article -
7
Machine Learning: Quantum vs Classical
Published in IEEE access (2020)“…Encouraged by growing computing power and algorithmic development, machine learning technologies have become powerful tools for a wide variety of application…”
Get full text
Journal Article -
8
Clinical phenotype, radiological features, and treatment of myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) optic neuritis
Published in Current opinion in neurology (01-02-2020)“…To review the clinical characteristics, radiological manifestations and treatment of myelin oligodendrocyte glycoprotein (MOG)-immunoglobulin G (IgG) optic…”
Get full text
Journal Article -
9
Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3
Published in Cell stem cell (04-08-2016)“…Emerging evidence from the current outbreak of Zika virus (ZIKV) indicates a strong causal link between Zika and microcephaly. To investigate how ZIKV…”
Get full text
Journal Article -
10
Immunopathogenesis of osteoarthritis
Published in Clinical immunology (Orlando, Fla.) (01-03-2013)“…Abstract Even though osteoarthritis (OA) is mainly considered as a degradative condition of the articular cartilage, there is increasing body of data…”
Get full text
Journal Article -
11
Tilted Optic Disc and Peripapillary Hyper-reflective Ovoid Mass-Like Structure
Published in Ophthalmology (Rochester, Minn.) (01-11-2023)Get full text
Journal Article -
12
ALKBH5 regulates anti–PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment
Published in Proceedings of the National Academy of Sciences - PNAS (18-08-2020)“…Although immune checkpoint blockade (ICB) therapy has revolutionized cancer treatment, many patients do not respond or develop resistance to ICB…”
Get full text
Journal Article -
13
Choroidal Neurofibromatosis
Published in Ophthalmology (Rochester, Minn.) (01-08-2023)Get full text
Journal Article -
14
Role of iNOS in osteoarthritis: Pathological and therapeutic aspects
Published in Journal of cellular physiology (01-10-2020)“…Accumulating evidence suggests that inflammation has a key role in the pathogenesis of osteoarthritis (OA). Nitric oxide (NO) has been established as one of…”
Get full text
Journal Article -
15
Nrf2/ARE pathway attenuates oxidative and apoptotic response in human osteoarthritis chondrocytes by activating ERK1/2/ELK1-P70S6K-P90RSK signaling axis
Published in Free radical biology & medicine (20-02-2018)“…Nrf2, a redox regulated transcription factor, has recently been shown to play a role in cartilage integrity but the mechanism remains largely unknown…”
Get full text
Journal Article -
16
Dynamics of Human and Viral RNA Methylation during Zika Virus Infection
Published in Cell host & microbe (09-11-2016)“…Infection with the flavivirus Zika (ZIKV) causes neurological, immunological, and developmental defects through incompletely understood mechanisms. We report…”
Get full text
Journal Article -
17
Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes
Published in Free radical biology & medicine (01-05-2017)“…Osteoarthritis (OA), characterized by progressive destruction of articular cartilage, is the most common form of human arthritis. Here, we evaluated the…”
Get full text
Journal Article -
18
Glial cell diversity and methamphetamine-induced neuroinflammation in human cerebral organoids
Published in Molecular psychiatry (01-04-2021)“…Methamphetamine (METH) is a potent stimulant that induces a euphoric state but also causes cognitive impairment, neurotoxicity and neurodevelopmental deficits…”
Get full text
Journal Article -
19
An Evolutionarily Conserved Long Noncoding RNA TUNA Controls Pluripotency and Neural Lineage Commitment
Published in Molecular cell (20-03-2014)“…Here, we generated a genome-scale shRNA library targeting long intergenic noncoding RNAs (lincRNAs) in the mouse. We performed an unbiased loss-of-function…”
Get full text
Journal Article -
20
Prevalence of potentially inappropriate medications use among older adults and risk factors using the 2015 American Geriatrics Society Beers criteria
Published in BMC geriatrics (29-05-2019)“…Older patients are commonly prescribed multiple medications therefore; medication misadventures are common and expected among older patients. The use of…”
Get full text
Journal Article