Search Results - "Tarighat, Somayeh S"

Bioassay Development for Bispecific Antibodies—Challenges and Opportunities by Register, Ames C., Tarighat, Somayeh S., Lee, Ho Young

“…Antibody therapeutics are expanding with promising clinical outcomes, and diverse formats of antibodies are further developed and available for patients of the…”
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Galectin-1 and Galectin-3 in B-Cell Precursor Acute Lymphoblastic Leukemia by Fei, Fei, Zhang, Mingfeng, Tarighat, Somayeh S, Joo, Eun Ji, Yang, Lu, Heisterkamp, Nora

“…Acute lymphoblastic leukemias arising from the malignant transformation of B-cell precursors (BCP-ALLs) are protected against chemotherapy by both intrinsic…”
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Overcoming Microenvironment-Mediated Chemoprotection through Stromal Galectin-3 Inhibition in Acute Lymphoblastic Leukemia by Tarighat, Somayeh S, Fei, Fei, Joo, Eun Ji, Abdel-Azim, Hisham, Yang, Lu, Geng, Huimin, Bum-Erdene, Khuchtumur, Grice, I Darren, von Itzstein, Mark, Blanchard, Helen, Heisterkamp, Nora

“…Environmentally-mediated drug resistance in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) significantly contributes to relapse. Stromal cells in the…”
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Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia by Blum, William, Schwind, Sebastian, Tarighat, Somayeh S., Geyer, Susan, Eisfeld, Ann-Kathrin, Whitman, Susan, Walker, Alison, Klisovic, Rebecca, Byrd, John C., Santhanam, Ramasamy, Wang, Hongyan, Curfman, John P., Devine, Steven M., Jacob, Samson, Garr, Celia, Kefauver, Cheryl, Perrotti, Danilo, Chan, Kenneth K., Bloomfield, Clara D., Caligiuri, Michael A., Grever, Michael R., Garzon, Ramiro, Marcucci, Guido

“…We recently reported promising clinical activity for a 10-day regimen of decitabine in older AML patients; high miR-29b expression associated with clinical…”
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B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3 by Fei, Fei, Joo, Eun Ji, Tarighat, Somayeh S, Schiffer, Isabelle, Paz, Helicia, Fabbri, Muller, Abdel-Azim, Hisham, Groffen, John, Heisterkamp, Nora

“…The molecular interactions between B-cell precursor acute lymphoblastic leukemia (pre-B ALL) cells and stromal cells in the bone marrow that provide…”
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Novel Selective Galectin‑3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia by Bum-Erdene, Khuchtumur, Collins, Patrick M, Hugo, Matthew W, Tarighat, Somayeh S, Fei, Fei, Kishor, Chandan, Leffler, Hakon, Nilsson, Ulf. J, Groffen, John, Grice, I. Darren, Heisterkamp, Nora, Blanchard, Helen

“…Galectin-3 is a β-galactoside-specific, carbohydrate-recognizing protein (lectin) that is strongly implicated in cancer development, metastasis, and drug…”
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CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms by Castillo, Joseph, Wu, Esther, Lowe, Christopher, Srinivasan, Shrividhya, McCord, Ron, Wagle, Marie-Claire, Jayakar, Sangeeta, Edick, Melissa Gonzalez, Eastham-Anderson, Jeffrey, Liu, Bonnie, Hutchinson, Katherine E, Jones, Wendell, Stokes, Matthew P, Tarighat, Somayeh S, Holcomb, Thomas, Glibicky, Andrew, Romero, F Anthony, Magnuson, Steven, Huang, Shih-Min A, Plaks, Vicki, Giltnane, Jennifer M, Lackner, Mark R, Mounir, Zineb

“…Regulatory T cells (Treg) are immunosuppressive and negatively impact response to cancer immunotherapies. CREB-binding protein (CBP) and p300 are closely…”
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Targeting the RAS/MAPK pathway with miR-181a in acute myeloid leukemia by Huang, Xiaomeng, Schwind, Sebastian, Santhanam, Ramasamy, Eisfeld, Ann-Kathrin, Chiang, Chi-Ling, Lankenau, Malori, Yu, Bo, Hoellerbauer, Pia, Jin, Yan, Tarighat, Somayeh S, Khalife, Jihane, Walker, Alison, Perrotti, Danilo, Bloomfield, Clara D, Wang, Hongyan, Lee, Robert J, Lee, Ly James, Marcucci, Guido

“…Deregulation of microRNAs' expression frequently occurs in acute myeloid leukemia (AML). Lower miR-181a expression is associated with worse outcomes, but the…”
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SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome by Alachkar, Houda, Santhanam, Ramasamy, Maharry, Kati, Metzeler, Klaus H, Huang, Xiaomeng, Kohlschmidt, Jessica, Mendler, Jason H, Benito, Juliana M, Hickey, Christopher, Neviani, Paolo, Dorrance, Adrienne M, Anghelina, Mirela, Khalife, Jihane, Tarighat, Somayeh S, Volinia, Stefano, Whitman, Susan P, Paschka, Peter, Hoellerbauer, Pia, Wu, Yue-Zhong, Han, Lina, Bolon, Brad N, Blum, William, Mrózek, Krzysztof, Carroll, Andrew J, Perrotti, Danilo, Andreeff, Michael, Caligiuri, Michael A, Konopleva, Marina, Garzon, Ramiro, Bloomfield, Clara D, Marcucci, Guido

“…Aberrant expression of the secreted protein, acidic, cysteine-rich (osteonectin) (SPARC) gene, which encodes a matricellular protein that participates in…”
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Morphometric Analysis of Sunflower (Helianthus annuus L.) Achenes from Mexico and Eastern North America by Tarighat, Somayeh S, Lentz, David L, Matter, Stephen F, Bye, Robert

“…Sunflower (Helianthus annuus L.) has played a major role in the evolution of agricultural systems in the Americas. The discovery of ancient domesticated…”
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The dual epigenetic role of PRMT5 in acute myeloid leukemia: gene activation and repression via histone arginine methylation by Tarighat, S S, Santhanam, R, Frankhouser, D, Radomska, H S, Lai, H, Anghelina, M, Wang, H, Huang, X, Alinari, L, Walker, A, Caligiuri, M A, Croce, C M, Li, L, Garzon, R, Li, C, Baiocchi, R A, Marcucci, G

“…Changes in the enzymatic activity of protein arginine methyltransferase (PRMT) 5 have been associated with cancer; however, the protein’s role in acute myeloid…”
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Increased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: a novel epigenetic-targeting approach in acute myeloid leukemia by Mims, A, Walker, A R, Huang, X, Sun, J, Wang, H, Santhanam, R, Dorrance, A M, Walker, C, Hoellerbauer, P, Tarighat, S S, Chan, K K, Klisovic, R B, Perrotti, D, Caligiuri, M A, Byrd, J C, Chen, C-S, James Lee, L, Jacob, S, Mrózek, K, Bloomfield, C D, Blum, W, Garzon, R, Schwind, S, Marcucci, G

“…Histone deacetylase (HDAC) inhibitors either alone or in combination with hypomethylating agents have limited clinical effect in acute myeloid leukemia (AML)…”
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Abstract 1128: Preclinical and pharmacological activities of protein arginine methyltransferase 5(PRMT5) enzyme inhibition in acute myeloid leukemia by Tarighat, Somayeh S., Mahasenan, Kiran, Perrotti, Danilo, Garzon, Ramiro, Caligiuri, Michael, Li, Chenglong, Blum, William, Marcucci, Guido, Baiocchi, Robert A.

“…Abstract With standard cytotoxic chemotherapy the majority of patients with Acute Myeloid Leukemia (AML) fail to achieve long term remission. Protein Arginine…”
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Morphometric Analysis of Sunflower (Helianthus annuus L.) Achenes from Mexico and Eastern North America^sup 1 by Tarighat, Somayeh S, Lentz, David L, Matter, Stephen F, Bye, Robert

“…Morphometric Analysis of Sunflower ( Helianthus annuus L.) Achenes from Mexico and Eastern North America. Sunflower (Helianthus annuus L.) has played a major…”
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Morphometric Analysis of Sunflower (Helianthus annuus L.) Achenes from Mexico and Eastern North America1 by Tarighat, Somayeh S., Lentz, David L., Matter, Stephen F., Bye, Robert

“…Morphometric Analysis of Sunflower ( Helianthus annuus L.) Achenes from Mexico and Eastern North America. Sunflower ( Helianthus annuus L . ) has played a…”
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