Search Results - "Targownik, L E"

A comparison of the gut microbiome between long‐term users and non‐users of proton pump inhibitors by Clooney, A. G., Bernstein, C. N, Leslie, W. D., Vagianos, K., Sargent, M., Laserna‐Mendieta, E. J., Claesson, M. J., Targownik, L. E.

“…Summary Background Proton pump inhibitor (PPI) use is associated with an increased risk of Clostridium difficile infection (CDI), though the mechanism is…”
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The effect of proton pump inhibitors on fracture risk: report from the Canadian Multicenter Osteoporosis Study by Fraser, L-A., Leslie, W. D., Targownik, L. E., Papaioannou, A., Adachi, J. D.

“…Summary A large Canadian cohort was studied over 10 years to see if proton pump inhibitor (PPI) use increased the risk of sustaining a fragility fracture. We…”
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Independent Validation of a Self-Report Version of the IBD Disability Index (IBDDI) in a Population-Based Cohort of IBD Patients by Shafer, LA, Walker, JR, Chhibba, T, Ivekovic, M, Singh, H, Targownik, LE, Peyrin-Biroulet, L, Gower-Rousseau, C, Sarter, H, Bernstein, CN

“…Abstract Introduction A new clinician-administered inflammatory bowel disease (IBD) Disability Index (IBDDI) was recently developed and validated among a…”
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Predicting complicated Crohn's disease and surgery: phenotypes, genetics, serology and psychological characteristics of a population‐based cohort by Ryan, J. D., Silverberg, M. S., Xu, W., Graff, L. A., Targownik, L. E., Walker, J. R., Carr, R., Clara, I., Miller, N., Rogala, L., Bernstein, C. N.

“…Summary Background Predictors of complicated Crohn's disease (CD), defined as stricturing or penetrating behaviour, and surgery have largely been derived from…”
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Gastrointestinal symptoms before and during menses in women with IBD by Bernstein, M. T., Graff, L. A., Targownik, L. E., Downing, K., Shafer, L. A., Rawsthorne, P., Bernstein, C. N., Avery, L.

“…Summary Background It is believed that women with inflammatory bowel disease (IBD) have heightened symptoms around their menses. However, there is little…”
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Differences in the management of Crohn’s disease among experts and community providers, based on a national survey of sample case vignettes by ESRAILIAN, E., SPIEGEL, B. M. R., TARGOWNIK, L. E., DUBINSKY, M. C., TARGAN, S. R., GRALNEK, I. M.

“…Summary Background  When faced with the same set of facts, healthcare providers often make different diagnoses, employ different tests and prescribe disparate…”
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Editorial: let's take a break from studying the PPI‐fracture association by Targownik, L. E.

“…Linked Content This article is linked to Torvinen‐Kiiskinen et al papers. To view these articles visit https://doi.org/10.1111/apt.14589 and…”
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Editorial: Non‐breaking news! High‐dose PPIs likely do not cause fractures by Targownik, L. E.

“…Linked Content This article is linked to Kumar et al. To view this article visit https://doi.org/10.1111/apt.14345…”
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Pre‐endoscopic proton pump inhibitor therapy reduces recurrent adverse gastrointestinal outcomes in patients with acute non‐variceal upper gastrointestinal bleeding by KEYVANI, L., MURTHY, S., LEESON, S., TARGOWNIK, L. E.

“…Summary Background Proton pump inhibitors (PPIs) following endoscopic haemostasis reduce rebleeding rates in patients with high‐risk acute non‐variceal upper…”
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Underutilization of gastroprotective strategies in aspirin users at increased risk of upper gastrointestinal complications by TARGOWNIK, L. E., METGE, C. J., LEUNG, S.

“…Summary Background  Aspirin use is with an increased risk of upper gastrointestinal complications (UGICs). Proton pump inhibitors (PPIs) decrease the risk of…”
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Physicians’ approaches to the use of gastroprotective strategies in low‐risk non‐steroidal anti‐inflammatory drug users by MURTHY, S. K., KAULDHER, S., TARGOWNIK, L. E.

“…Summary Background Many doctors unnecessarily prescribe gastroprotective strategies to non‐steroidal anti‐inflammatory drugs users at low risk of non‐steroidal…”
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The prevalence of risk factors for gastrointestinal complications and use of gastroprotection among persons hospitalized for cardiovascular disease by TARGOWNIK, L. E., AL‐MAMFUD, A.

“…Summary Background Aspirin is often used in patients with cardiovascular disease, but it can also cause gastrointestinal complications. Proton pump inhibitors…”
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Use of proton pump inhibitors and risk of osteoporosis-related fractures by Targownik, Laura E, Lix, Lisa M, Metge, Colleen J, Prior, Heather J, Leung, Stella, Leslie, William D

“…The use of proton pump inhibitors has been associated with an increased risk of hip fracture. We sought to further explore the relation between duration of…”
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Editorial: Non‐breaking news! High‐dose PPI s likely do not cause fractures by Targownik, L. E.

“…Linked Content This article is linked to Kumar et al. To view this article visit https://doi.org/10.1111/apt.14345 …”
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An assessment of endoscopic and concomitant management of acute variceal bleeding at a tertiary care centre by Singh, H, Targownik, L E, Ward, G, Minuk, G Y, Bernstein, C N

“…Several therapies have been demonstrated to be beneficial in the management of acute variceal bleeding (AVB). The aim of the present study was to characterize…”
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P672 Occurrence of malignancy among infliximab biosimilar and bio-originator initiators in Canada: a comparative population-based analysis by Birck, M G, Lukusa, L, Singh, H, Narula, N, Targownik, L E, Leung, Y, Afif, W, Bernatsky, S

“…Abstract Background Infliximab (INF) downregulates the immune system. Given the immune system's role in deleting pre-cancerous cells, malignancy is a potential…”
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P725 Trends in biologic use prior to resective surgery for inflammatory bowel disease: A Canadian population-based study by Chopra, D, Kennedy, E, Weizman, A V, Tennakoon, A, Targownik, L E

“…Abstract Background Despite advances in medical therapy for inflammatory bowel disease (IBD), surgery is required in 50–80% of patients with Crohn’s disease…”
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A74 URGENCY FOR BOWEL MOVEMENTS IS A HIGHLY DISCRIMINATORY SYMPTOM FOR ACTIVE DISEASE IN PERSONS WITH IBD (THE MANITOBA LIVING WITH IBD STUDY) by Kulyk, A, Shafer, L A, Graff, L A, Stone, J, Witges, K, Targownik, L E, Bernstein, C

“…Abstract Background The Inflammatory Bowel Disease Symptom Inventory (IBDSI) is a validated patient self-reported measure used to assess IBD disease activity…”
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A168 COSTS OF MISSED WORK AMONG PEOPLE WITH INFLAMMATORY BOWEL DISEASE: A CROSS-SECTIONAL POPULATION-REPRESENTATIVE STUDY by Kuenzig, E, Lebenbaum, M, Mason, J, Vyas, M V, Kaplan, G G, Murthy, S K, Targownik, L E, Benchimol, E I

“…Abstract Background The relapsing and remitting symptoms experienced by people with inflammatory bowel disease (IBD), including abdominal pain and diarrhea,…”
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Immortal time bias and infliximab-related mortality and malignancy incidence by Targownik, Laura Ellyn

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