Search Results - "Targoff, Ira"

Anti-Ro52 autoantibodies are associated with interstitial lung disease and more severe disease in patients with juvenile myositis by Sabbagh, Sara, Pinal-Fernandez, Iago, Kishi, Takayuki, Targoff, Ira N, Miller, Frederick W, Rider, Lisa G, Mammen, Andrew Lee

“…Anti-Ro52 autoantibodies are associated with more severe interstitial lung disease (ILD) in adult myositis patients with antiaminoacyl transfer (t)RNA…”
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The Myositis Autoantibody Phenotypes of the Juvenile Idiopathic Inflammatory Myopathies by Rider, Lisa G., Shah, Mona, Mamyrova, Gulnara, Huber, Adam M., Rice, Madeline Murguia, Targoff, Ira N., Miller, Frederick W.

“…The juvenile idiopathic inflammatory myopathies (JIIM) are systemic autoimmune diseases characterized by skeletal muscle weakness, characteristic rashes, and…”
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Anti-MDA5 autoantibodies associated with juvenile dermatomyositis constitute a distinct phenotype in North America by Mamyrova, Gulnara, Kishi, Takayuki, Shi, Min, Targoff, Ira N, Huber, Adam M, Curiel, Rodolfo V, Miller, Frederick W, Rider, Lisa G

“…Abstract Objective Myositis-specific autoantibodies have defined distinct phenotypes of patients with juvenile myositis (JIIM). We assessed the frequency and…”
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Expression of interferon-regulated genes in juvenile dermatomyositis versus Mendelian autoinflammatory interferonopathies by Kim, Hanna, Gunter-Rahman, Fatima, McGrath, John A, Lee, Esther, de Jesus, Adriana A, Targoff, Ira N, Huang, Yan, O'Hanlon, Terrance P, Tsai, Wanxia L, Gadina, Massimo, Miller, Frederick W, Goldbach-Mansky, Raphaela, Rider, Lisa G

“…Juvenile dermatomyositis (JDM) is a systemic autoimmune disease with a prominent interferon (IFN) signature, but the pathogenesis of JDM and the etiology of…”
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The Clinical Phenotypes of the Juvenile Idiopathic Inflammatory Myopathies by Shah, Mona, Mamyrova, Gulnara, Targoff, Ira N., Huber, Adam M., Malley, James D., Rice, Madeline Murguia, Miller, Frederick W., Rider, Lisa G.

“…The juvenile idiopathic inflammatory myopathies (JIIM) are systemic autoimmune diseases characterized by skeletal muscle weakness, characteristic rashes, and…”
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Clinical cardiac involvement in idiopathic inflammatory myopathies: A systematic review by Gupta, Raghav, Wayangankar, Siddharth A, Targoff, Ira N, Hennebry, Thomas A

“…Abstract Background Idiopathic inflammatory myopathies (IIM) presenting with diffuse skeletal muscular inflammation and cardiac involvement is one of the major…”
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Anti-NT5C1A autoantibodies are associated with more severe disease in patients with juvenile myositis by Yeker, Richard M, Pinal-Fernandez, Iago, Kishi, Takayuki, Pak, Katherine, Targoff, Ira N, Miller, Frederick W, Rider, Lisa G, Mammen, Andrew L

“…Autoantibodies recognising cytosolic 5'-nucleotidase 1A (NT5C1A) are found in adult patients with myositis and other autoimmune diseases. They are especially…”
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Corticosteroid discontinuation, complete clinical response and remission in juvenile dermatomyositis by Kishi, Takayuki, Warren-Hicks, William, Bayat, Nastaran, Targoff, Ira N, Huber, Adam M, Ward, Michael M, Rider, Lisa G

“…Abstract Objective A North American registry of JDM patients was examined for frequency of and factors associated with corticosteroid discontinuation, complete…”
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Heterogeneity of autoantibodies in 100 patients with autoimmune myositis: insights into clinical features and outcomes by Koenig, Martial, Fritzler, Marvin J, Targoff, Ira N, Troyanov, Yves, Senécal, Jean-Luc

“…The objective of this study was to determine the prevalence, mutual associations, clinical manifestations, and diagnoses associated with serum autoantibodies,…”
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Redefining Dermatomyositis: A Description of New Diagnostic Criteria That Differentiate Pure Dermatomyositis From Overlap Myositis With Dermatomyositis Features by Troyanov, Yves, Targoff, Ira N, Payette, Marie-Pier, Raynauld, Jean-Pierre, Chartier, Suzanne, Goulet, Jean-Richard, Bourré-Tessier, Josiane, Rich, Eric, Grodzicky, Tamara, Fritzler, Marvin J., Joyal, France, Koenig, Martial, Senécal, Jean-Luc

“…Dermatomyositis (DM) is a major clinical subset of autoimmune myositis (AIM). The characteristic DM rash (Gottron papules, heliotrope rash) and perifascicular…”
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Long-term outcomes in Juvenile Myositis patients by Tsaltskan, Vladislav, Aldous, Annette, Serafi, Sam, Yakovleva, Anna, Sami, Heidi, Mamyrova, Gulnara, Targoff, Ira N., Schiffenbauer, Adam, Miller, Frederick W., Simmens, Samuel J., Curiel, Rodolfo, Jones, Olcay Y., Rider, Lisa G.

“…Juvenile idiopathic inflammatory myopathies (JIIM) are rare, chronic autoimmune muscle diseases of childhood, with the potential for significant morbidity…”
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Association of anti-HSC70 autoantibodies with cutaneous ulceration and severe disease in juvenile dermatomyositis by Karasawa, Rie, Yudoh, Kazuo, Sato, Toshiko, Tanaka, Megumi, Tamaki, Mayumi, Sabbagh, Sara E, O’Hanlon, Terrance P, Noroozi-Farhadi, Payam, Targoff, Ira N, Flegel, Willy A, Mammen, Andrew L, Miller, Frederick W, Hicar, Mark D, Rider, Lisa G, Jarvis, James N

“…Abstract Objectives JDM is an inflammatory myopathy characterized by prominent vasculopathy. AECAs are frequently detected in inflammatory and autoimmune…”
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Autoantibodies Recognizing Specificity Protein 4 Co‐occur With Anti–Transcription Intermediary Factor 1 and Are Associated With Distinct Clinical Features and Immunogenetic Risk Factors in Juvenile Myositis by Sherman, Matthew A., Pak, Katherine, Pinal‐Fernandez, Iago, Flegel, Willy A., Targoff, Ira N., Miller, Frederick W., Rider, Lisa G., Mammen, Andrew L., Albert, Daniel A., Arabshahi, Bita, Balboni, Imelda M., Ballinger, Susan, Bayat, Nastaran, Bingham, C. April, Bohnsack, John F., Cartwright, Victoria W., Cron, Randy Q., Curiel, Rodolfo, Pena, Wendy, Guzman, Marietta M., Eberhardt, Barbara Anne, Edelheit, Barbara S., Farhadi, Payam Noroozi, Finkel, Terri H., Fuhlbrigge, Robert C., Gewanter, Harry L., Goldmuntz, Ellen A., Gottlieb, Beth S., Griffin, Thomas A., Groh, Brandt P., Hannan, William P., Hawkins‐Holt, Melissa, Henrickson, Michael, Higgins, Gloria C., Imundo, Lisa, Jansen, Anna, Jarvis, James, Jones, Olcay Y., Kamdar, Ankur, Kim, Hanna, Kingsbury, Daniel J., Kishi, Takayuki, Lindsley, Carol B., Mamyrova, Gulnara, McCarthy, Paul L., Mitchell, Stephen R., Nanda, Kabita, Nativ, Simona, Oral, Elif A., Pachman, Lauren M., Perez, Maria D., Person, Donald A., Rabinovich, Egla C., Ronis, Tova, Sabbagh, Sara E., Sarkar, Kakali, Schiffenbauer, Adam, Shaham, Bracha, Soep, Jennifer, Stoll, Matthew L., Sule, Sangeeta, Tarvin, Stacey E., Taylor‐Albert, Elizabeth, Vogelgesang, Scott A., Volochayev, Rita, White, Patience H.

“…Objective Autoantibodies recognizing specificity protein 4 (Sp4) were recently discovered in adults with idiopathic inflammatory myopathies (IIM). Anti‐Sp4…”
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Autoantibodies and their significance in myositis by Targoff, Ira N.

“…Myositis autoantibodies continue to be the subject of substantial interest, with several significant recent developments. Recent studies have emphasized that…”
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Early Illness Features Associated With Mortality in the Juvenile Idiopathic Inflammatory Myopathies by Huber, Adam M., Mamyrova, Gulnara, Lachenbruch, Peter A., Lee, Julia A., Katz, James D., Targoff, Ira N., Miller, Frederick W., Rider, Lisa G.

“…Objective Because juvenile idiopathic inflammatory myopathies (IIMs) are potentially life‐threatening systemic autoimmune diseases, we examined risk factors…”
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The effect of cigarette smoking on the clinical and serological phenotypes of polymyositis and dermatomyositis by Schiffenbauer, Adam, Faghihi-Kashani, Sara, O'Hanlon, Terrence P., Flegel, Willy A., Adams, Sharon D., Targoff, Ira N., Oddis, Chester V., Ytterberg, Steven R., Aggarwal, Rohit, Christopher-Stine, Lisa, Shamim, Ejaz A., Dellaripa, Paul F., Danoff, Sonye K., Mammen, Andrew L., Miller, Frederick W.

“…Cigarette smoking is associated with immune-mediated disorders. We explored the contribution of smoking to polymyositis (PM) and dermatomyositis (DM)…”
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Novel Classification of Idiopathic Inflammatory Myopathies Based on Overlap Syndrome Features and Autoantibodies: Analysis of 100 French Canadian Patients by Troyanov, Yves, Targoff, Ira N., Tremblay, Jean-Luc, Goulet, Jean-Richard, Raymond, Yves, Senécal, Jean-Luc

“…Our objective was to improve the currently imperfect classifications of idiopathic inflammatory myopathies (IIM). In clinical practice, overlap features are…”
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Atorvastatin-induced necrotizing autoimmune myositis: An emerging dominant entity in patients with autoimmune myositis presenting with a pure polymyositis phenotype by Troyanov, Yves, Landon-Cardinal, Océane, Fritzler, Marvin J., Ferreira, José, Targoff, Ira N., Rich, Eric, Goulet, Michelle, Goulet, Jean-Richard, Bourré-Tessier, Josiane, Robitaille, Yves, Drouin, Julie, Albert, Alexandra, Senécal, Jean-Luc

“…The general aim of this study was to evaluate the disease spectrum in patients presenting with a pure polymyositis (pPM) phenotype. Specific objectives were to…”
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Environmental factors associated with juvenile idiopathic inflammatory myopathy clinical and serologic phenotypes by Scalabrini, Jonathan C, Schiffenbauer, Adam I, Farhadi, Payam Noroozi, Volochayev, Rita, Bayat, Nastaran, Jansen, Anna, Targoff, Ira N, Miller, Frederick W, Rider, Lisa G

“…Environmental exposures have been associated with the juvenile idiopathic inflammatory myopathies (JIIM). We undertook a questionnaire-based study to evaluate…”
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Features distinguishing clinically amyopathic juvenile dermatomyositis from juvenile dermatomyositis by Mamyrova, Gulnara, Kishi, Takayuki, Targoff, Ira N, Ehrlich, Alison, Curiel, Rodolfo V, Rider, Lisa G

“…Abstract Objective We examined features of clinically amyopathic JDM (CAJDM), in which patients have characteristic rashes with little to no evidence of muscle…”
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