Search Results - "Tarca, Adi L"

A comparison of gene set analysis methods in terms of sensitivity, prioritization and specificity by Tarca, Adi L, Bhatti, Gaurav, Romero, Roberto

“…Identification of functional sets of genes associated with conditions of interest from omics data was first reported in 1999, and since, a plethora of…”
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Does the human placenta express the canonical cell entry mediators for SARS-CoV-2? by Pique-Regi, Roger, Romero, Roberto, Tarca, Adi L, Luca, Francesca, Xu, Yi, Alazizi, Adnan, Leng, Yaozhu, Hsu, Chaur-Dong, Gomez-Lopez, Nardhy

“…The pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected more than 10…”
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Single cell transcriptional signatures of the human placenta in term and preterm parturition by Pique-Regi, Roger, Romero, Roberto, Tarca, Adi L, Sendler, Edward D, Xu, Yi, Garcia-Flores, Valeria, Leng, Yaozhu, Luca, Francesca, Hassan, Sonia S, Gomez-Lopez, Nardhy

“…More than 135 million births occur each year; yet, the molecular underpinnings of human parturition in gestational tissues, and in particular the placenta, are…”
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Maternal-fetal immune responses in pregnant women infected with SARS-CoV-2 by Garcia-Flores, Valeria, Romero, Roberto, Xu, Yi, Theis, Kevin R., Arenas-Hernandez, Marcia, Miller, Derek, Peyvandipour, Azam, Bhatti, Gaurav, Galaz, Jose, Gershater, Meyer, Levenson, Dustyn, Pusod, Errile, Tao, Li, Kracht, David, Florova, Violetta, Leng, Yaozhu, Motomura, Kenichiro, Para, Robert, Faucett, Megan, Hsu, Chaur-Dong, Zhang, Gary, Tarca, Adi L., Pique-Regi, Roger, Gomez-Lopez, Nardhy

“…Pregnant women represent a high-risk population for severe/critical COVID-19 and mortality. However, the maternal-fetal immune responses initiated by…”
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Evidence of perturbations of the cytokine network in preterm labor by Romero, Roberto, MD, DMedSci, Grivel, Jean-Charles, PhD, Tarca, Adi L., PhD, Chaemsaithong, Piya, MD, Xu, Zhonghui, MSc, Fitzgerald, Wendy, BS, Hassan, Sonia S., MD, Chaiworapongsa, Tinnakorn, MD, Margolis, Leonid, PhD

“…Objective Intraamniotic inflammation/infection is the only mechanism of disease with persuasive evidence of causality for spontaneous preterm labor/delivery…”
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The prediction of early preeclampsia: Results from a longitudinal proteomics study by Tarca, Adi L, Romero, Roberto, Benshalom-Tirosh, Neta, Than, Nandor Gabor, Gudicha, Dereje W, Done, Bogdan, Pacora, Percy, Chaiworapongsa, Tinnakorn, Panaitescu, Bogdan, Tirosh, Dan, Gomez-Lopez, Nardhy, Draghici, Sorin, Hassan, Sonia S, Erez, Offer

“…To identify maternal plasma protein markers for early preeclampsia (delivery <34 weeks of gestation) and to determine whether the prediction performance is…”
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The prediction of late-onset preeclampsia: Results from a longitudinal proteomics study by Erez, Offer, Romero, Roberto, Maymon, Eli, Chaemsaithong, Piya, Done, Bogdan, Pacora, Percy, Panaitescu, Bogdan, Chaiworapongsa, Tinnakorn, Hassan, Sonia S, Tarca, Adi L

“…Late-onset preeclampsia is the most prevalent phenotype of this syndrome; nevertheless, only a few biomarkers for its early diagnosis have been reported. We…”
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Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor by Bhatti, Gaurav, Romero, Roberto, Rice, Gregory Edward, Fitzgerald, Wendy, Pacora, Percy, Gomez-Lopez, Nardhy, Kavdia, Mahendra, Tarca, Adi L, Margolis, Leonid

“…Amniotic fluid cytokines have been implicated in the mechanisms of preterm labor and birth. Cytokines can be packaged within or on the surface of extracellular…”
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Single and Serial Fetal Biometry to Detect Preterm and Term Small- and Large-for-Gestational-Age Neonates: A Longitudinal Cohort Study by Tarca, Adi L, Hernandez-Andrade, Edgar, Ahn, Hyunyoung, Garcia, Maynor, Xu, Zhonghui, Korzeniewski, Steven J, Saker, Homam, Chaiworapongsa, Tinnakorn, Hassan, Sonia S, Yeo, Lami, Romero, Roberto

“…To assess the value of single and serial fetal biometry for the prediction of small- (SGA) and large-for-gestational-age (LGA) neonates delivered preterm or at…”
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Analysis of microarray experiments of gene expression profiling by Tarca, Adi L., Romero, Roberto, Draghici, Sorin

“…The study of gene expression profiling of cells and tissue has become a major tool for discovery in medicine. Microarray experiments allow description of…”
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The Maternal Plasma Proteome Changes as a Function of Gestational Age in Normal Pregnancy: a Longitudinal Study by Romero, Roberto, MD, D.Med.Sci, Erez, Offer, MD, Maymon, Eli, MD, Chaemsaithong, Piya, MD, Xu, Zhonghui, MSc, Pacora, Percy, MD, Chaiworapongsa, Tinnakorn, MD, Done, Bogdan, MD, Hassan, Sonia S., MD, Tarca, Adi L., PhD

“…Abstract Objective Pregnancy is accompanied by dramatic physiologic changes in maternal plasma proteins. Characterization of the maternal plasma proteome in…”
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The plasma metabolome of women in early pregnancy differs from that of non-pregnant women by Handelman, Samuel K, Romero, Roberto, Tarca, Adi L, Pacora, Percy, Ingram, Brian, Maymon, Eli, Chaiworapongsa, Tinnakorn, Hassan, Sonia S, Erez, Offer

“…In comparison to the non-pregnant state, the first trimester of pregnancy is characterized by systemic adaptation of the mother. The extent to which these…”
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A Role for the Inflammasome in Spontaneous Labor at Term by Romero, Roberto, Xu, Yi, Plazyo, Olesya, Chaemsaithong, Piya, Chaiworapongsa, Tinnakorn, Unkel, Ronald, Than, Nandor Gabor, Chiang, Po Jen, Dong, Zhong, Xu, Zhonghui, Tarca, Adi L., Abrahams, Vikki M., Hassan, Sonia S., Yeo, Lami, Gomez‐Lopez, Nardhy

“…Problem Inflammasomes are signaling platforms that, upon sensing pathogens and sterile stressors, mediate the release of mature forms of interleukin (IL)‐1β…”
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The amniotic fluid proteome changes with gestational age in normal pregnancy: a cross-sectional study by Bhatti, Gaurav, Romero, Roberto, Gomez-Lopez, Nardhy, Chaiworapongsa, Tinnakorn, Jung, Eunjung, Gotsch, Francesca, Pique-Regi, Roger, Pacora, Percy, Hsu, Chaur-Dong, Kavdia, Mahendra, Tarca, Adi L.

“…The cell-free transcriptome in amniotic fluid (AF) has been shown to be informative of physiologic and pathologic processes in pregnancy; however, the change…”
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Eicosanomic profiling reveals dominance of the epoxygenase pathway in human amniotic fluid at term in spontaneous labor by Maddipati, Krishna Rao, Romero, Roberto, Chaiworapongsa, Tinnakorn, Zhou, Sen‐Lin, Xu, Zhonghui, Tarca, Adi L., Kusanovic, Juan Pedro, Munoz, Hernan, Honn, Kenneth V.

“…Lipid mediators play an important role in reproductive biology, especially, in parturition. Enhanced biosynthesis of eicosanoids, such as prostaglandin E2…”
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The Cellular Transcriptome in the Maternal Circulation During Normal Pregnancy: A Longitudinal Study by Gomez-Lopez, Nardhy, Romero, Roberto, Hassan, Sonia S, Bhatti, Gaurav, Berry, Stanley M, Kusanovic, Juan Pedro, Pacora, Percy, Tarca, Adi L

“…Pregnancy represents a unique immunological state in which the mother adapts to tolerate the semi-allogenic conceptus; yet, the cellular dynamics in the…”
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Machine learning and its applications to biology by Tarca, Adi L, Carey, Vincent J, Chen, Xue-wen, Romero, Roberto, Drăghici, Sorin

“…[...]a section reviews methods and examples as implemented in the open source data analysis and visualization language R (http://www.r-project.org). The goal…”
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Maternal whole blood mRNA signatures identify women at risk of early preeclampsia: a longitudinal study by Tarca, Adi L., Romero, Roberto, Erez, Offer, Gudicha, Dereje W., Than, Nandor Gabor, Benshalom-Tirosh, Neta, Pacora, Percy, Hsu, Chaur-Dong, Chaiworapongsa, Tinnakorn, Hassan, Sonia S., Gomez-Lopez, Nardhy

“…To determine whether previously established mRNA signatures are predictive of early preeclampsia when evaluated by maternal cellular transcriptome analysis in…”
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Distinct Cellular Immune Responses to SARS-CoV-2 in Pregnant Women by Gomez-Lopez, Nardhy, Romero, Roberto, Tao, Li, Gershater, Meyer, Leng, Yaozhu, Zou, Chengrui, Farias-Jofre, Marcelo, Galaz, Jose, Miller, Derek, Tarca, Adi L, Arenas-Hernandez, Marcia, Bhatti, Gaurav, Garcia-Flores, Valeria, Liu, Zhenjie, Para, Robert, Kanninen, Tomi, Hadaya, Ola, Paredes, Carmen, Xu, Yi

“…Pregnant women are at increased risk of adverse outcomes, including preeclampsia and preterm birth, that may result from severe acute respiratory syndrome…”
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Exhausted and Senescent T Cells at the Maternal-Fetal Interface in Preterm and Term Labor by Leng, Yaozhu, Gomez-Lopez, Nardhy, Hassan, Sonia S., Tarca, Adi L., Done, Bogdan, Miller, Derek, Galaz, Jose, Xu, Yi, Romero, Roberto, Slutsky, Rebecca, Gregor, Sabrina

“…Successful pregnancy requires a tightly-regulated equilibrium of immune cell interactions at the maternal-fetal interface (i.e., the decidual tissues), which…”
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