Search Results - "Taratula, Olena R"
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Nanomedicines for Improved Management of Ectopic Pregnancy: A Narrative Review
Published in Small (Weinheim an der Bergstrasse, Germany) (01-10-2024)“…Ectopic pregnancy (EP) – the implantation of an embryo outside of the endometrial cavity, often in the fallopian tube – is a significant contributor to…”
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Development and Perspectives: Multifunctional Nucleic Acid Nanomedicines for Treatment of Gynecological Cancers
Published in Small (Weinheim an der Bergstrasse, Germany) (01-10-2024)“…Gynecological malignancies are a significant cause of morbidity and mortality across the globe. Due to delayed presentation, gynecological cancer patients are…”
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Novel Nanoparticle-Based Treatment and Imaging Modalities
Published in Pharmaceutics (11-01-2023)“…Over the last twenty years, nanomaterials have been widely used in cancer research [...]…”
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Systemically Delivered Magnetic Hyperthermia for Prostate Cancer Treatment
Published in Pharmaceutics (25-10-2020)“…Herein, we report a novel therapy for prostate cancer based on systemically delivered magnetic hyperthermia. Conventional magnetic hyperthermia is a form of…”
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From Bench to Bedside: Implications of Lipid Nanoparticle Carrier Reactogenicity for Advancing Nucleic Acid Therapeutics
Published in Pharmaceuticals (Basel, Switzerland) (31-07-2023)“…In biomedical applications, nanomaterial-based delivery vehicles, such as lipid nanoparticles, have emerged as promising instruments for improving the…”
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Increasing lean muscle mass in mice via nanoparticle-mediated hepatic delivery of follistatin mRNA
Published in Theranostics (01-01-2018)“…Muscle atrophy occurs during chronic diseases, resulting in diminished quality of life and compromised treatment outcomes. There is a high demand for…”
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Targeted Nanomedicine for Suppression of CD44 and Simultaneous Cell Death Induction in Ovarian Cancer: An Optimal Delivery of siRNA and Anticancer Drug
Published in Clinical cancer research (15-11-2013)“…The proposed project is aimed at enhancing the efficiency of epithelial ovarian cancer treatment and reducing adverse side effects of chemotherapy using…”
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Glutathione‐Responsive Methotrexate Polymersomes for Potential Management of Ectopic Pregnancy
Published in Small (Weinheim an der Bergstrasse, Germany) (01-10-2024)“…The first‐line treatment for ectopic pregnancy (EP), the chemotherapeutic methotrexate (MTX), has a failure rate of more than 10%, which can lead to severe…”
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Targeted Nanoparticles with High Heating Efficiency for the Treatment of Endometriosis with Systemically Delivered Magnetic Hyperthermia
Published in Small (Weinheim an der Bergstrasse, Germany) (01-06-2022)“…Endometriosis is a devastating disease in which endometrial‐like tissue forms lesions outside the uterus. It causes infertility and severe pelvic pain in ≈176…”
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Nanoparticle‐Based Platform for Activatable Fluorescence Imaging and Photothermal Ablation of Endometriosis
Published in Small (Weinheim an der Bergstrasse, Germany) (01-05-2020)“…Endometriosis is a painful disorder where endometrium‐like tissue forms lesions outside of the uterine cavity. Intraoperative identification and removal of…”
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Lipid Nanoparticles Elicit Reactogenicity and Sickness Behavior in Mice Via Toll-Like Receptor 4 and Myeloid Differentiation Protein 88 Axis
Published in ACS nano (10-09-2024)“…mRNA therapeutics encapsulated in lipid nanoparticles (LNPs) offer promising avenues for treating various diseases. While mRNA vaccines anticipate…”
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Targeted Nanocarriers for Systemic Delivery of IRAK4 Inhibitors to Inflamed Tissues
Published in Small (Weinheim an der Bergstrasse, Germany) (01-01-2024)“…Persistent and uncontrolled inflammation is the root cause of various debilitating diseases. Given that interleukin‐1 receptor‐associated kinase 4 (IRAK4) is a…”
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Nano‐Theranostic Modality for Visualization of the Placenta and Photo‐Hyperthermia for Potential Management of Ectopic Pregnancy
Published in Small (Weinheim an der Bergstrasse, Germany) (01-01-2023)“…Ectopic pregnancy (EP) is the leading cause of maternity‐related death in the first trimester of pregnancy. Approximately 98% of ectopic implantations occur in…”
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Poly(aspartic acid)-Based Polymeric Nanoparticle for Local and Systemic mRNA Delivery
Published in Molecular pharmaceutics (05-12-2022)“…Recently, therapeutics based on mRNA (mRNA) have attracted significant interest for vaccines, cancer immunotherapy, and gene editing. However, the lack of…”
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Nanoparticle‐Based Follistatin Messenger RNA Therapy for Reprogramming Metastatic Ovarian Cancer and Ameliorating Cancer‐Associated Cachexia
Published in Small (Weinheim an der Bergstrasse, Germany) (01-11-2022)“…This study presents the first messenger RNA (mRNA) therapy for metastatic ovarian cancer and cachexia‐induced muscle wasting based on lipid nanoparticles that…”
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Transarterial Delivery of a Biodegradable Single-Agent Theranostic Nanoprobe for Liver Tumor Imaging and Combinatorial Phototherapy
Published in Journal of vascular and interventional radiology (01-09-2019)“…To assess selective accumulation of biodegradable nanoparticles within hepatic tumors after transarterial delivery for in vivo localization and combinatorial…”
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A Photoacoustic Contrast Nanoagent with a Distinct Spectral Signature for Ovarian Cancer Management
Published in Advanced healthcare materials (01-04-2023)“…Photoacoustic imaging (PAI) has tremendous potential for improving ovarian cancer detection. However, the lack of effective exogenous contrast agents that can…”
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An Advanced Thermal Decomposition Method to Produce Magnetic Nanoparticles with Ultrahigh Heating Efficiency for Systemic Magnetic Hyperthermia
Published in Small methods (01-12-2022)“…Due to the limited heating efficiency of available magnetic nanoparticles, it is difficult to achieve therapeutic temperatures above 44 °C in relatively…”
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Endometriosis Treatment: Nanoparticle‐Based Platform for Activatable Fluorescence Imaging and Photothermal Ablation of Endometriosis (Small 18/2020)
Published in Small (Weinheim an der Bergstrasse, Germany) (01-05-2020)“…In article number 1906936, Ov D. Slayden, Oleh Taratula, and co‐workers present a nanomedicine approach for endometriosis treatment. Photo‐responsive…”
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Development and Perspectives: Multifunctional Nucleic Acid Nanomedicines for Treatment of Gynecological Cancers (Small 41/2024)
Published in Small (Weinheim an der Bergstrasse, Germany) (10-10-2024)“…Gynecological Cancers The female reproductive system nurtures humanity's future while battling its own fragility. Gynecological cancers pose a significant…”
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