Search Results - "Taratula, Oleh"

Nanostructured lipid carriers as multifunctional nanomedicine platform for pulmonary co-delivery of anticancer drugs and siRNA by Taratula, Oleh, Kuzmov, Andriy, Shah, Milin, Garbuzenko, Olga B., Minko, Tamara

“…We developed, synthesized, and tested a multifunctional nanostructured lipid nanocarrier-based system (NLCS) for efficient delivery of an anticancer drug and…”
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Co-delivery of Doxorubicin and Bcl-2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug-Resistant Cancer Cells by Chen, Alex M., Zhang, Min, Wei, Dongguang, Stueber, Dirk, Taratula, Oleh, Minko, Tamara, He, Huixin

“…Co‐delivery of Doxorubicin and siRNAs by mesoporous silica nanoparticles into multidrug‐resistance cancer cells with minimal premature release significantly…”
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Dendrimer-encapsulated naphthalocyanine as a single agent-based theranostic nanoplatform for near-infrared fluorescence imaging and combinatorial anticancer phototherapy by Taratula, Olena, Schumann, Canan, Duong, Tony, Taylor, Karmin L, Taratula, Oleh

“…Multifunctional theranostic platforms capable of concurrent near-infrared (NIR) fluorescence imaging and phototherapies are strongly desired for cancer…”
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Innovative strategy for treatment of lung cancer: targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA by Taratula, Oleh, Garbuzenko, Olga B., Chen, Alex M., Minko, Tamara

“…A tumor targeted mesoporous silica nanoparticles (MSN)-based drug delivery system (DDS) was developed for inhalation treatment of lung cancer. The system was…”
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LHRH-Targeted Drug Delivery Systems for Cancer Therapy by Li, Xiaoning, Taratula, Oleh, Taratula, Olena, Schumann, Canan, Minko, Tamara

“…Targeted delivery of therapeutic and diagnostic agents to cancer sites has significant potential to improve the therapeutic outcome of treatment while…”
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A Multifunctional Theranostic Platform Based on Phthalocyanine-Loaded Dendrimer for Image-Guided Drug Delivery and Photodynamic Therapy by Taratula, Olena, Schumann, Canan, Naleway, Michael A, Pang, Addison J, Chon, Kaitlyn J, Taratula, Oleh

“…Owing to the outstanding near-infrared (NIR) optical properties, phthalocyanines (Pc) have promising potential as theranostic agents for fluorescence…”
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Novel Nanoparticle-Based Treatment and Imaging Modalities by Taratula, Oleh, Taratula, Olena R

“…Over the last twenty years, nanomaterials have been widely used in cancer research [...]…”
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Internally Cationic Polyamidoamine PAMAM-OH Dendrimers for siRNA Delivery: Effect of the Degree of Quaternization and Cancer Targeting by Patil, Mahesh L, Zhang, Min, Taratula, Oleh, Garbuzenko, Olga B, He, Huixin, Minko, Tamara

“…A novel cancer targeted, internally cationic and surface neutral polyamidoamine (PAMAM) dendrimer, was designed, synthesized, and evaluated as a nanocarrier…”
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Naphthalocyanine-Based Biodegradable Polymeric Nanoparticles for Image-Guided Combinatorial Phototherapy by Taratula, Olena, Doddapaneni, Bhuvana S, Schumann, Canan, Li, Xiaoning, Bracha, Shay, Milovancev, Milan, Alani, Adam W. G, Taratula, Oleh

“…Image-guided phototherapy is extensively considered as a promising therapy for cancer treatment. To enhance translational potential of this modality, we…”
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Phototheranostic nanoplatform based on a single cyanine dye for image-guided combinatorial phototherapy by Duong, Tony, Li, Xiaoning, PhD, Yang, Bona, Schumann, Canan, PharmD, Albarqi, Hassan A., MS, Taratula, Olena, PhD, Taratula, Oleh, PhD

“…Abstract This study represents a novel phototheranostic nanoplatform based on the near-infrared (NIR) heptamethine cyanine dye, IR775, which is capable of…”
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Surface-Modified and Internally Cationic Polyamidoamine Dendrimers for Efficient siRNA Delivery by Patil, Mahesh L, Zhang, Min, Betigeri, Seema, Taratula, Oleh, He, Huixin, Minko, Tamara

“…A novel internally quaternized and surface-acetylated poly(amidoamine) generation four dendrimer (QPAMAM-NHAc) was synthesized and evaluated for intracellular…”
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Anti-HER2 IgY antibody-functionalized single-walled carbon nanotubes for detection and selective destruction of breast cancer cells by Xiao, Yan, Gao, Xiugong, Taratula, Oleh, Treado, Stephen, Urbas, Aaron, Holbrook, R David, Cavicchi, Richard E, Avedisian, C Thomas, Mitra, Somenath, Savla, Ronak, Wagner, Paul D, Srivastava, Sudhir, He, Huixin

“…Nanocarrier-based antibody targeting is a promising modality in therapeutic and diagnostic oncology. Single-walled carbon nanotubes (SWNTs) exhibit two unique…”
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Systemically Delivered Magnetic Hyperthermia for Prostate Cancer Treatment by Albarqi, Hassan A., Demessie, Ananiya A., Sabei, Fahad Y., Moses, Abraham S., Hansen, Mikkel N., Dhagat, Pallavi, Taratula, Olena R., Taratula, Oleh

“…Herein, we report a novel therapy for prostate cancer based on systemically delivered magnetic hyperthermia. Conventional magnetic hyperthermia is a form of…”
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From Bench to Bedside: Implications of Lipid Nanoparticle Carrier Reactogenicity for Advancing Nucleic Acid Therapeutics by Korzun, Tetiana, Moses, Abraham S, Diba, Parham, Sattler, Ariana L, Taratula, Olena R, Sahay, Gaurav, Taratula, Oleh, Marks, Daniel L

“…In biomedical applications, nanomaterial-based delivery vehicles, such as lipid nanoparticles, have emerged as promising instruments for improving the…”
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Multifunctional nanomedicine platform for cancer specific delivery of siRNA by superparamagnetic iron oxide nanoparticles-dendrimer complexes by Taratula, Oleh, Garbuzenko, Olga, Savla, Ronak, Wang, Y Andrew, He, Huixin, Minko, Tamara

“…The ability of Superparamagnetic Iron Oxide (SPIO) nanoparticles and Poly(Propyleneimine) generation 5 dendrimers (PPI G5) to cooperatively provoke siRNA…”
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DNA Photocleavage in the Near-Infrared Wavelength Range by 2-Quinolinium Dicarbocyanine Dyes by Ahoulou, Effibe O, Drinkard, Kaitlyn K, Basnet, Kanchan, St Lorenz, Anna, Taratula, Oleh, Henary, Maged, Grant, Kathryn B

“…Here, we report the syntheses of two pentamethine cyanine dyes containing quinolinium rings and substituted with either hydrogen ( ) or bromine ( ) at the…”
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Inhalation treatment of lung cancer： the influence of composition, size and shape of nanocarriers on their lung accumulation and retention by Garbuzenko, Olga B, Mainelis, Gediminas, Taratula, Oleh, Minko, Tamara

“…Objective： Various nanoparticles have been designed and tested in order to select optimal carriers for the inhalation delivery ofanticancer drugs to the lungs…”
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ROS-induced nanotherapeutic approach for ovarian cancer treatment based on the combinatorial effect of photodynamic therapy and DJ-1 gene suppression by Schumann, Canan, PharmD, Taratula, Olena, PhD, Khalimonchuk, Oleh, PhD, Palmer, Amy L., MS, Cronk, Lauren M, Jones, Carson V., BS, Escalante, Cesar A., BS, Taratula, Oleh, PhD

“…Abstract This study represents a novel approach for intraoperative ovarian cancer treatment based on the combinatorial effect of a targeted photodynamic…”
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A Preliminary Proteomic Investigation of Circulating Exosomes and Discovery of Biomarkers Associated with the Progression of Osteosarcoma in a Clinical Model of Spontaneous Disease by Brady, Jacqueline V., Troyer, Ryan M., Ramsey, Stephen A., Leeper, Haley, Yang, Liping, Maier, Claudia S., Goodall, Cheri P., Ruby, Carl E., Albarqi, Hassan A.M., Taratula, Oleh, Bracha, Shay

“…Circulating cancer exosomes are microvesicles which originate from malignant cells and other organs influenced by the disease and can be found in blood. The…”
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Increasing lean muscle mass in mice via nanoparticle-mediated hepatic delivery of follistatin mRNA by Schumann, Canan, Nguyen, Duc X, Norgard, Mason, Bortnyak, Yulia, Korzun, Tetiana, Chan, Stephanie, Lorenz, Anna St, Moses, Abraham S, Albarqi, Hassan A, Wong, Leon, Michaelis, Katherine, Zhu, Xinxia, Alani, Adam W G, Taratula, Olena R, Krasnow, Stephanie, Marks, Daniel L, Taratula, Oleh

“…Muscle atrophy occurs during chronic diseases, resulting in diminished quality of life and compromised treatment outcomes. There is a high demand for…”
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