Search Results - "Tarasova, Olga S."
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Myography of isolated blood vessels: Considerations for experimental design and combination with supplementary techniques
Published in Frontiers in physiology (24-04-2023)“…The study of the mechanisms of regulation of vascular tone is an urgent task of modern science, since diseases of the cardiovascular system remain the main…”
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Changes in Endothelial Nitric Oxide Production in Systemic Vessels during Early Ontogenesis-A Key Mechanism for the Perinatal Adaptation of the Circulatory System
Published in International journal of molecular sciences (21-03-2019)“…Nitric oxide (NO) produced in the wall of blood vessels is necessary for the regulation of vascular tone to ensure an adequate blood supply of organs and…”
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The Effects of Acidosis on eNOS in the Systemic Vasculature: A Focus on Early Postnatal Ontogenesis
Published in International journal of molecular sciences (26-05-2022)“…The activity of many vasomotor signaling pathways strongly depends on extracellular/intracellular pH. Nitric oxide (NO) is one of the most important…”
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Remodeling of Arterial Tone Regulation in Postnatal Development: Focus on Smooth Muscle Cell Potassium Channels
Published in International journal of molecular sciences (21-05-2021)“…Maturation of the cardiovascular system is associated with crucial structural and functional remodeling. Thickening of the arterial wall, maturation of the…”
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Thyroxine Induces Acute Relaxation of Rat Skeletal Muscle Arteries via Integrin αvβ3, ERK1/2 and Integrin-Linked Kinase
Published in Frontiers in physiology (14-09-2021)“…Aim: Hyperthyroidism is associated with a decreased peripheral vascular resistance, which could be caused by the vasodilator genomic or non-genomic effects of…”
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MAPKs Are Highly Abundant but Do Not Contribute to α1-Adrenergic Contraction of Rat Saphenous Arteries in the Early Postnatal Period
Published in International journal of molecular sciences (03-06-2021)“…Previously, the abundance of p42/44 and p38 MAPK proteins had been shown to be higher in arteries of 1- to 2-week-old compared to 2- to 3-month-old rats…”
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Intrauterine growth restriction weakens anticontractile influence of NO in coronary arteries of adult rats
Published in Scientific reports (14-07-2021)“…Intrauterine growth restriction (IUGR) is one of the most common pathologies of pregnancy. The cardiovascular consequences of IUGR do not disappear in…”
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TWIK-Related Acid-Sensitive Potassium Channels (TASK-1) Emerge as Contributors to Tone Regulation in Renal Arteries at Alkaline pH
Published in Frontiers in physiology (20-05-2022)“…TASK-1 channels are established regulators of pulmonary artery tone but their contribution to the regulation of vascular tone in systemic arteries is poorly…”
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Intrauterine Nitric Oxide Deficiency Weakens Differentiation of Vascular Smooth Muscle in Newborn Rats
Published in International journal of molecular sciences (01-08-2021)“…Nitric oxide (NO) deficiency during pregnancy is a key reason for preeclampsia development. Besides its important vasomotor role, NO is shown to regulate the…”
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Trophic sympathetic influence weakens pro-contractile role of Cl− channels in rat arteries during postnatal maturation
Published in Scientific reports (17-11-2020)“…Membrane transporters and their functional contribution in vasculature change during early postnatal development. Here we tested the hypothesis that the…”
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Pannexin 1 Transgenic Mice: Human Diseases and Sleep-Wake Function Revision
Published in International journal of molecular sciences (17-05-2021)“…In humans and other vertebrates pannexin protein family was discovered by homology to invertebrate gap junction proteins. Several biological functions were…”
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Voluntary wheel exercise training affects locomotor muscle, but not the diaphragm in the rat
Published in Frontiers in physiology (26-10-2022)“…Introduction: Functional tests and training regimens intensity-controlled by an individual are used in sport practice, clinical rehabilitation, and space…”
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Phase Coupling Between Baroreflex Oscillations of Blood Pressure and Heart Rate Changes in 21-Day Dry Immersion
Published in Frontiers in physiology (21-05-2020)“…Dry immersion (DI) is a ground-based experimental model which reproduces the effects of microgravity on the cardiovascular system and, therefore, can be used…”
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Intrauterine L-NAME Exposure Weakens the Development of Sympathetic Innervation and Induces the Remodeling of Arterial Vessels in Two-Week-Old Rats
Published in International journal of molecular sciences (15-11-2021)“…Nitric oxide (NO) has been shown to stimulate differentiation and increase the survival of ganglionic sympathetic neurons. The proportion of neuronal…”
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Endothelial nitric oxide weakens arterial contractile responses and reduces blood pressure during early postnatal development in rats
Published in Nitric oxide (01-05-2016)“…During maturation the vascular system undergoes structural and functional remodeling. At the systemic level it results in a gradual increase of arterial blood…”
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Simulated Microgravity Induces Regionally Distinct Neurovascular and Structural Remodeling of Skeletal Muscle and Cutaneous Arteries in the Rat
Published in Frontiers in physiology (30-06-2020)“…: Mechanical forces and sympathetic influences are key determinants of vascular structure and function. This study tested the hypothesis that hindlimb…”
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Pannexins Are Potential New Players in the Regulation of Cerebral Homeostasis during Sleep-Wake Cycle
Published in Frontiers in cellular neuroscience (17-07-2017)“…During brain homeostasis, both neurons and astroglia release ATP that is rapidly converted to adenosine in the extracellular space. Pannexin-1 (Panx1)…”
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Region-specific effects of antenatal/early postnatal hypothyroidism on endothelial NO-pathway activity in systemic circulation
Published in Current research in physiology (01-01-2022)“…Antenatal/early postnatal hypothyroidism weakens NO-mediated anticontractile influence of endothelium in coronary arteries of adult rats, but it remains…”
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Negative feedback regulation of vasocontraction by potassium channels in 10‐ to 15‐day‐old rats: Dominating role of Kv7 channels
Published in Acta Physiologica (01-02-2019)“…Aim Potassium channels are key regulators of smooth muscle membrane potential and arterial tone. However, the roles of potassium channels in vascular tone…”
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Pannexin 1 facilitates arterial relaxation via an endothelium-derived hyperpolarization mechanism
Published in FEBS letters (28-04-2015)“…•We studied endothelium-dependent relaxations in control (WT) and Panx1−/− (KO) mice.•The EDH-like component of endothelium-dependent relaxation is impaired in…”
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