Search Results - "Taran, Fréderic"

Translocation of Poly(ethylene glycol-co-hexadecyl)cyanoacrylate Nanoparticles into Rat Brain Endothelial Cells:  Role of Apolipoproteins in Receptor-Mediated Endocytosis by Kim, Hyun R, Andrieux, Karine, Gil, Sophie, Taverna, Myriam, Chacun, Héléne, Desmaële, Didier, Taran, Fréderic, Georgin, Dominique, Couvreur, Patrick

“…Previous in vivo observations in rats have shown that poly(ethylene glycol) polyhexadecylcyanoacrylate (PEG-PHDCA) nanoparticles could translocate into the…”
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Analysis of plasma protein adsorption onto PEGylated nanoparticles by complementary methods: 2-DE, CE and Protein Lab-on-chip® system by Kim, Hyun Ryoung, Andrieux, Karine, Delomenie, Claudine, Chacun, Héléne, Appel, Martine, Desmaële, Didier, Taran, Fréderic, Georgin, Dominique, Couvreur, Patrick, Taverna, Myriam

“…The biodistribution of colloidal carriers after their administration in vivo depends on the adsorption of some plasma proteins and apolipoproteins on their…”
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Click and Bio-Orthogonal Reactions with Mesoionic Compounds by Porte, Karine, Riomet, Margaux, Figliola, Carlotta, Audisio, Davide, Taran, Frédéric

“…Click and bio-orthogonal reactions are dominated by cycloaddition reactions in general and 1,3-dipolar cycloadditions in particular. Among the dipoles…”
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Dodecyl creatine ester and lipid nanocapsule: a double strategy for the treatment of creatine transporter deficiency by Trotier-Faurion, Alexandra, Passirani, Catherine, Béjaud, Jérôme, Dézard, Sophie, Valayannopoulos, Vassili, Taran, Fréderic, de Lonlay, Pascale, Benoit, Jean-Pierre, Mabondzo, Aloïse

“…Creatine transporter (CT) deficiency is characterized by mutations in the gene encoding CT, leading to impaired transport of creatine at the cell membrane…”
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Dynamic Carbon Isotope Exchange of Pharmaceuticals with Labeled CO2 by Destro, Gianluca, Loreau, Olivier, Marcon, Elodie, Taran, Frédéric, Cantat, Thibault, Audisio, Davide

“…A copper-catalyzed procedure enabling dynamic carbon isotope exchange is described. Utilizing the universal precursor [14C]­CO2, this protocol allows to…”
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Sydnone-alkyne cycloaddition: applications in synthesis and bioconjugation by Decuypère, Elodie, Plougastel, Lucie, Audisio, Davide, Taran, Frédéric

“…Sydnones are among the most popular mesoionic compounds studied so far for cycloaddition reactions. However, despite their good chemical stability and…”
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Late-Stage Carbon-14 Labeling and Isotope Exchange: Emerging Opportunities and Future Challenges by Babin, Victor, Taran, Frédéric, Audisio, Davide

“…Carbon-14 (14C) is a gold standard technology routinely utilized in pharmaceutical and agrochemical industries for tracking synthetic organic molecules and…”
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Iridium-Catalyzed Cycloaddition of Azides and 1‑Bromoalkynes at Room Temperature by Rasolofonjatovo, Evelia, Theeramunkong, Sewan, Bouriaud, Alexandra, Kolodych, Sergii, Chaumontet, Manon, Taran, Frédéric

“…Iridium dimer complexes were found to catalyze the [3 + 2] cycloaddition reaction of azides with bromoalkynes, yielding 1,5-disubstituted…”
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Platform for Multiple Isotope Labeling via Carbon–Sulfur Bond Exchange by Mouhsine, Bouchaib, Norlöff, Maylis, Ghouilem, Juba, Sallustrau, Antoine, Taran, Frédéric, Audisio, Davide

“…In this work, we explore a nickel-catalyzed reversible carbon–sulfur (C–S) bond activation strategy to achieve selective sulfur isotope exchange. Isotopes are…”
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One-Pot Synthesis of 1,4-Disubstituted Pyrazoles from Arylglycines via Copper-Catalyzed Sydnone–Alkyne Cycloaddition Reaction by Specklin, Simon, Decuypere, Elodie, Plougastel, Lucie, Aliani, Soifia, Taran, Frédéric

“…A robust method for constructing 1,4-pyrazoles from arylglycines was developed using the copper-catalyzed sydnone–alkyne cycloaddition reaction. The procedure…”
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Modern Strategies for Carbon Isotope Exchange by Labiche, Alexandre, Malandain, Augustin, Molins, Maxime, Taran, Frédéric, Audisio, Davide

“…In contrast to stable and natural abundant carbon‐12, the synthesis of organic molecules with carbon (radio)isotopes must be conceived and optimized in order…”
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Photochemical Strategy for Carbon Isotope Exchange with CO2 by Babin, Victor, Talbot, Alex, Labiche, Alexandre, Destro, Gianluca, Del Vecchio, Antonio, Elmore, Charles S, Taran, Frédéric, Sallustrau, Antoine, Audisio, Davide

“…A photocatalytic approach for carbon isotope exchange is reported. Utilizing [13C]­CO2 and [14C]­CO2 as primary C1 sources, this protocol allows the insertion…”
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Carbon Dioxide Radical Anion by Photoinduced Equilibration between Formate Salts and [11C, 13C, 14C]CO2: Application to Carbon Isotope Radiolabeling by Malandain, Augustin, Molins, Maxime, Hauwelle, Alexandre, Talbot, Alex, Loreau, Olivier, D’Anfray, Timothée, Goutal, Sébastien, Tournier, Nicolas, Taran, Frédéric, Caillé, Fabien, Audisio, Davide

“…The need for carbon-labeled radiotracers is increasingly higher in drug discovery and development (carbon-14, β–, t 1/2 = 5730 years) as well as in positron…”
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2′-Modified Thymidines with Bioorthogonal Cyclopropene or Sydnone as Building Blocks for Copper-Free Postsynthetic Functionalization of Chemically Synthesized Oligonucleotides by Bristiel, Alexandra, Cadinot, Manon, Pizzonero, Mathieu, Taran, Frédéric, Urban, Dominique, Guignard, Raphaël, Guianvarc’h, Dominique

“…The development of facile methods for conjugating relevant probes, ligands, or delivery agents onto oligonucleotides (ONs) is highly desirable both for…”
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Access to N‑Carbonyl Derivatives of Iminosydnones by Carbonylimidazolium Activation by Riomet, Margaux, Porte, Karine, Madegard, Léa, Thuéry, Pierre, Audisio, Davide, Taran, Frédéric

“…A new methodology for N-exocyclic functionalization of iminosydnones was developed involving the addition of a large variety of nucleophiles on…”
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Dramatic Effect of the Gelling Cation on the Catalytic Performances of Alginate-Supported Palladium Nanoparticles for the Suzuki–Miyaura Reaction by Chtchigrovsky, Mélanie, Lin, Yi, Ouchaou, Kahina, Chaumontet, Manon, Robitzer, Mike, Quignard, Françoise, Taran, Frédéric

“…This work describes the preparation and characterization of a library of alginate-supported palladium nanoparticles together with their catalytic capabilities…”
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Sydnone-Based Approach to Heterohelicenes through 1,3-Dipolar-Cycloadditions by Yen-Pon, Expédite, Champagne, Pier Alexandre, Plougastel, Lucie, Gabillet, Sandra, Thuéry, Pierre, Johnson, Mizuki, Muller, Gilles, Pieters, Grégory, Taran, Frédéric, Houk, K. N, Audisio, Davide

“…The first approach to pyrazole-containing helicenes via sydnone-aryne [3 + 2]-cycloaddition is described. An unprecedented regioselectivity in the…”
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Copper-Chelating Azides for Efficient Click Conjugation Reactions in Complex Media by Bevilacqua, Valentina, King, Mathias, Chaumontet, Manon, Nothisen, Marc, Gabillet, Sandra, Buisson, David, Puente, Céline, Wagner, Alain, Taran, Frédéric

“…The concept of chelation‐assisted copper catalysis was employed for the development of new azides that display unprecedented reactivity in the…”
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Copper(I)-Catalyzed Cycloaddition of 4‑Bromosydnones and Alkynes for the Regioselective Synthesis of 1,4,5-Trisubstituted Pyrazoles by Decuypere, Elodie, Specklin, Simon, Gabillet, Sandra, Audisio, Davide, Liu, Hui, Plougastel, Lucie, Kolodych, Sergii, Taran, Frédéric

“…Copper-catalyzed cycloaddition of alkynes with 4-bromosydnones provides a convenient, mild, and regioselective method for the synthesis of a wide range of…”
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Direct Carbon Isotope Exchange of Pharmaceuticals via Reversible Decyanation by Feng, Minghao, De Oliveira, Joao, Sallustrau, Antoine, Destro, Gianluca, Thuéry, Pierre, Roy, Sebastien, Cantat, Thibault, Elmore, Charles S, Blankenstein, Jorg, Taran, Frédéric, Audisio, Davide

“…The incorporation of carbon-14 allows tracking of organic molecules and provides vital knowledge on their fate. This information is critical in pharmaceutical…”
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