Search Results - "Tappe, William"

A Meta-Analysis Evaluating the Incidence of Bleeding Events With Intravenous Defibrotide Treatment Outside the Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Setting by Tappe, William, Aggarwal, Saurabh, Topaloglu, Ozlem, Iacobelli, Massimo

“…Defibrotide is approved to treat hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) with renal/pulmonary dysfunction following…”
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A Meta-Analysis Evaluating the Risk of Bleeding-Related Adverse Events with Defibrotide Treatment by Tappe, William, Aggarwal, Saurabh, Topaloglu, Ozlem, Iacobelli, Massimo

“…Introduction: Defibrotide is approved for adult and pediatric patients with hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) with renal…”
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Study Design of an Open-Label, Single-Arm, Multicenter, Phase 2 Study to Evaluate the Safety and Efficacy of Defibrotide in Adult Patients with Transplant-Associated Thrombotic Microangiopathy by Ho, Vincent T., Keshelava, Nino, Swann, Suzanne, Tappe, William

“…Background: Transplant-associated thrombotic microangiopathy (TA-TMA) is an uncommon, but well-recognized, hematopoietic cell transplant (HCT) complication…”
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Final results from a defibrotide treatment‐IND study for patients with hepatic veno‐occlusive disease/sinusoidal obstruction syndrome by Kernan, Nancy A., Grupp, Stephan, Smith, Angela R., Arai, Sally, Triplett, Brandon, Antin, Joseph H., Lehmann, Leslie, Shore, Tsiporah, Ho, Vincent T., Bunin, Nancy, Iacobelli, Massimo, Liang, Wei, Hume, Robin, Tappe, William, Soiffer, Robert, Richardson, Paul

“…Summary Hepatic veno‐occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a potentially life‐threatening complication of haematopoietic stem cell…”
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A Pooled Analysis of Survival By Defibrotide Timing of Initiation in Adults with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Following Hematopoietic Stem Cell Transplant (HSCT) by Richardson, Paul, Carreras, Enric, Pagliuca, Antonio, Ryan, Robert, Tappe, William, Mohty, Mohamad

“…Introduction Hepatic VOD/SOS is a potentially life-threatening complication of HSCT or of nontransplant-associated high-dose chemotherapy. VOD/SOS associated…”
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Incidence of Post-Hematopoietic Stem Cell Transplantation (HSCT) Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) without Hyperbilirubinemia at Diagnosis and Efficacy of Defibrotide in an Expanded-Access Program by Corbacioglu, Selim, Kernan, Nancy A., Pagliuca, Antonio, Ryan, Robert, Tappe, William, Richardson, Paul

“…Introduction Hepatic VOD/SOS is a progressive, potentially life-threatening complication early post-HSCT, or of nontransplant chemotherapy. VOD/SOS diagnosis…”
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Pooled analysis of Day 100 survival for defibrotide‐treated patients with hepatic veno‐occlusive disease/sinusoidal obstruction syndrome and ventilator or dialysis dependence following haematopoietic cell transplantation by Richardson, Paul G., Smith, Angela R., Kernan, Nancy A., Lehmann, Leslie, Soiffer, Robert J., Ryan, Robert J., Tappe, William, Grupp, Stephan

“…Summary For patients with untreated hepatic veno‐occlusive disease (VOD)/sinusoidal obstruction syndrome (SOS) with multi‐organ dysfunction (MOD), mortality is…”
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Diagnosis of Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) with or without Multi-Organ Dysfunction (MOD) after Hematopoietic Stem Cell Transplantation (HSCT): Analysis of a Multicenter Chart Review by Doede, Tina, Viddam, Anusha, Villa, Kathleen F., Hannah, Alison L., Weaver, Charles H., Tappe, William

“…Background: VOD/SOS, a potentially life-threatening complication of HSCT conditioning, has historically been diagnosed using modified Seattle criteria (≥2 of:…”
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Defibrotide for the treatment of hepatic veno‐occlusive disease/sinusoidal obstruction syndrome following nontransplant‐associated chemotherapy: Final results from a post hoc analysis of data from an expanded‐access program by Kernan, Nancy A., Richardson, Paul G., Smith, Angela R., Triplett, Brandon M., Antin, Joseph H., Lehmann, Leslie, Messinger, Yoav, Liang, Wei, Hume, Robin, Tappe, William, Soiffer, Robert J., Grupp, Stephan A.

“…Background Hepatic veno‐occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a potentially fatal complication of conditioning for hematopoietic stem…”
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Adults Receiving Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT): Final Results from the Expanded-Access Program by Richardson, Paul G, Antin, Joseph H., Giralt, Sergio A., Ryan, Robert J., Liang, Wei, Hume, Robin L., Tappe, William Martin, Kernan, Nancy A.

“…Background VOD/SOS is an unpredictable, potentially life-threatening complication of conditioning regimens for HSCT or chemotherapy without HSCT. VOD/SOS with…”
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Pooled Analysis of Day +100 Survival for Defibrotide-Treated Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) and Ventilator or Dialysis Dependence Following Hematopoietic Stem Cell Transplantation (HSCT) by Richardson, Paul G, Smith, Angela R., Kernan, Nancy A., Antin, Joseph H., Lehmann, Leslie, Ryan, Robert J., Hume, Robin L., Tappe, William Martin, Grupp, Stephan A

“…Background VOD/SOS is an unpredictable, potentially life-threatening complication of conditioning regimens for HSCT or chemotherapy without HSCT, and has been…”
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Efficacy and Safety of Defibrotide in Pediatric Patients with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT): Final Results from the Expanded-Access Program by Kernan, Nancy A., Smith, Angela R., Triplett, Brandon, Lehmann, Leslie, Ryan, Robert J., Liang, Wei, Hume, Robin L., Tappe, William Martin, Grupp, Stephan A

“…Background VOD/SOS is an unpredictable, potentially life-threatening complication of conditioning regimens for HSCT or post-chemotherapy without HSCT. VOD/SOS…”
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Final Analysis of Day +100 Survival By Prior Hematopoietic Stem Cell Transplant Type from an Expanded Access Study of Defibrotide for Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome by Richardson, Paul G, Smith, Angela R., Triplett, Brandon, Kernan, Nancy, Lehmann, Leslie, Ryan, Robert J., Hume, Robin L., Tappe, William Martin, Grupp, Stephan A

“…Background Hepatic veno-occlusive disease (VOD), also known as sinusoidal obstruction syndrome (SOS), is an unpredictable, life-threatening complication of…”
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Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Post-Hematopoietic Stem Cell Transplantation (HSCT) in Patients with Neuroblastoma: Final Data from the Defibrotide Expanded-Access Program by Grupp, Stephan A, Triplett, Brandon, Marachelian, Araz, Jodele, Sonata, Ryan, Robert J., Hume, Robin L., Tappe, William Martin, Richardson, Paul G

“…Background VOD/SOS is a potentially life-threatening complication of HSCT conditioning, with a reported mean incidence of 13.7%. VOD/SOS with multi-organ…”
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Efficacy and safety of defibrotide (DF) to treat hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) after primary chemotherapy (CT): A post hoc analysis of final data by Kernan, Nancy A., Richardson, Paul G., Triplett, Brandon, Grupp, Stephan A., Antin, Joseph Harry, Messinger, Yoav H., Liang, Wei, Hume, Robin, Tappe, William, Soiffer, Robert

“…Abstract only 10513 Background: VOD/SOS, which may be unpredictable and potentially life-threatening, is typically considered a complication of hematopoietic…”
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Timing of Initiation of Defibrotide Post-Diagnosis of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Post-Hematopoietic Stem Cell Transplantation: Exploratory Age-Group Analysis from an Expanded Access Study by Grupp, Stephan A., Smith, Angela R., Triplett, Brandon M., Kernan, Nancy A., Antin, Joseph H., Lehmann, Leslie, Liang, Wei, Hume, Robin, Tappe, William, Richardson, Paul G.

“…Introduction Hepatic veno-occlusive disease, also called sinusoidal obstruction syndrome (VOD/SOS), is a potentially life-threatening complication of…”
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Efficacy and Safety of Defibrotide to Treat Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) After Primary Chemotherapy: A Post Hoc Analysis of Final Data From an Expanded-Access Protocol by Kernan, Nancy, Antin, Joseph, Messinger, Yoav, Liang, Wei, Hume, Robin, Tappe, William, Richardson, Paul

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Timing of initiation of defibrotide (DF) post-diagnosis of hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) after hematopoietic stem cell transplantation (HSCT): Final data from an expanded-access protocol by Grupp, Stephan A., Richardson, Paul G., Smith, Angela R., Triplett, Brandon, Kernan, Nancy A., Antin, Joseph Harry, Lehmann, Leslie, Giralt, Sergio, Liang, Wei, Hume, Robin, Tappe, William, Soiffer, Robert

“…Abstract only 7047 Background: VOD/SOS is an unpredictable, potentially life-threatening complication of HSCT. VOD/SOS with multi-organ dysfunction (MOD) may…”
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Impact on Outcomes of Baseline Bilirubin in Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Receiving Defibrotide Treatment: A Post-Hoc Analysis by Richardson, Paul G., Smith, Angela R., Triplett, Brandon M., Kernan, Nancy A., Grupp, Stephan A., Antin, Joseph H., Lehmann, Leslie, Liang, Wei, Hume, Robin, Tappe, William, Soiffer, Robert J.

“…Introduction Hepatic veno-occlusive disease, also called sinusoidal obstruction syndrome (VOD/SOS), is a difficult to predict, and potentially life-threatening…”
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Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Post-Hematopoietic Stem Cell Transplantation (HSCT) in Patients with Acute Leukemias: A Subgroup Analysis from the Defibrotide Expanded-Access Program by Richardson, Paul G., Smith, Angela R., Triplett, Brandon M., Kernan, Nancy A., Grupp, Stephan A., Antin, Joseph H., Lehmann, Leslie, Liang, Wei, Hume, Robin, Tappe, William, Soiffer, Robert J.

“…Introduction Hepatic veno-occlusive disease, also called sinusoidal obstruction syndrome (VOD/SOS), is an unpredictable, potentially life-threatening…”
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