Search Results - "Tapken, Ines"

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    What could be the function of the spinal muscular atrophy-causing protein SMN in macrophages? by Tapken, Ines, Detering, Nora T, Claus, Peter

    Published in Frontiers in immunology (28-05-2024)
    “…Spinal Muscular Atrophy (SMA), a neurodegenerative disorder, extends its impact beyond the nervous system. The central protein implicated in SMA, Survival…”
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    Journal Article
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    bootGSEA: a bootstrap and rank aggregation pipeline for multi-study and multi-omics enrichment analyses by Hemandhar Kumar, Shamini, Tapken, Ines, Kuhn, Daniela, Claus, Peter, Jung, Klaus

    Published in Frontiers in bioinformatics (03-04-2024)
    “…Gene set enrichment analysis (GSEA) subsequent to differential expression analysis is a standard step in transcriptomics and proteomics data analysis. Although…”
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    Dysregulation of Tweak and Fn14 in skeletal muscle of spinal muscular atrophy mice by Meijboom, Katharina E., Sutton, Emma R., McCallion, Eve, McFall, Emily, Anthony, Daniel, Edwards, Benjamin, Kubinski, Sabrina, Tapken, Ines, Bünermann, Ines, Hazell, Gareth, Ahlskog, Nina, Claus, Peter, Davies, Kay E., Kothary, Rashmi, Wood, Matthew J. A., Bowerman, Melissa

    Published in Skeletal muscle (28-07-2022)
    “…Abstract Background Spinal muscular atrophy (SMA) is a childhood neuromuscular disorder caused by depletion of the survival motor neuron (SMN) protein. SMA is…”
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  6. 6

    From data to discovery: AI-guided analysis of disease-relevant molecules in spinal muscular atrophy (SMA) by Tapken, Ines, Kuhn, Daniela, Hoffmann, Nico, Detering, Nora T, Schüning, Tobias, Billaud, Jean-Noël, Tugendreich, Stuart, Schlüter, Nadine, Green, Jeff, Krämer, Andreas, Claus, Peter

    Published in Human molecular genetics (22-07-2024)
    “…Spinal Muscular Atrophy is caused by partial loss of survival of motoneuron (SMN) protein expression. The numerous interaction partners and mechanisms…”
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    Journal Article
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