Search Results - "Tapial, Sandra"
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A clinico-pathological and molecular analysis reveals differences between solitary (early and late-onset) and synchronous rectal cancer
Published in Scientific reports (26-01-2021)“…Rectal cancer (RC) appears to behave differently compared with colon cancer. We aimed to analyze existence of different subtypes of RC depending on distinct…”
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Copy neutral loss of heterozygosity (cnLOH) patterns in synchronous colorectal cancer
Published in European journal of human genetics : EJHG (01-04-2021)“…Copy neutral loss of heterozygosity (cnLOH) is a common event in several human malignancies-positing this as a mechanism of carcinogenesis. However, the role…”
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Intermediate-onset colorectal cancer: A clinical and familial boundary between both early and late-onset colorectal cancer
Published in PloS one (16-05-2019)“…Comparative studies of colorectal cancer (CRC) according to the age of onset have found differences between early-onset CRC (EOCRC) and late-onset CRC (LOCRC)…”
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Cimp-Positive Status is More Representative in Multiple Colorectal Cancers than in Unique Primary Colorectal Cancers
Published in Scientific reports (19-07-2019)“…Colorectal cancer (CRC) with CpG island methylator phenotype (CIMP) is recognized as a subgroup of CRC that shows association with particular genetic defects…”
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Redefining synchronous colorectal cancers based on tumor clonality
Published in International journal of cancer (01-04-2019)“…To analyze the possible clonal origin of a part of Synchronous colorectal cancer (SCRC), we studied 104 paired‐SCRCs from 52 consecutive patients without…”
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Contribution of New Adenomatous Polyposis Predisposition Genes in an Unexplained Attenuated Spanish Cohort by Multigene Panel Testing
Published in Scientific reports (08-07-2019)“…Attenuated adenomatous polyposis (AAP) is a heterogeneous syndrome in terms of clinical manifestations, heritability and etiology of the disease. Genetic…”
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Comment on ‘Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system’
Published in British journal of cancer (06-02-2018)Get full text
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Differential clinicopathological and molecular features within late-onset colorectal cancer according to tumor location
Published in Oncotarget (16-03-2018)“…Since there is a predilection of some clinical and molecular features for a given tumor location, we assessed whether this can be confirmed in late-onset…”
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Cohort profile: the Spanish Early-onset Colorectal Cancer (SECOC) cohort: a multicentre cohort study on the molecular basis of colorectal cancer among young individuals in Spain
Published in BMJ open (30-12-2021)“…PurposeThe Spanish Early-onset Colorectal Cancer (SECOC) study is a multicentre prospective cohort established in Spain to investigate the molecular basis of…”
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Association of Polyps with Early-Onset Colorectal Cancer and Throughout Surveillance: Novel Clinical and Molecular Implications
Published in Cancers (29-11-2019)“…Early-onset colorectal cancer (EOCRC) is an increasing and worrisome entity. The aim of this study was to analyze its association with polyps concerning…”
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