Search Results - "Tapia, Victor E."
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Cellular Mechanotransduction Relies on Tension-Induced and Chaperone-Assisted Autophagy
Published in Current biology (04-03-2013)“…Mechanical tension is an ever-present physiological stimulus essential for the development and homeostasis of locomotory, cardiovascular, respiratory, and…”
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The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1
Published in Biochimica et biophysica acta. Molecular cell research (01-01-2017)“…The cochaperone BAG3 is a central protein homeostasis factor in mechanically strained mammalian cells. It mediates the degradation of unfolded and damaged…”
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Y65C Missense Mutation in the WW Domain of the Golabi-Ito-Hall Syndrome Protein PQBP1 Affects Its Binding Activity and Deregulates Pre-mRNA Splicing
Published in The Journal of biological chemistry (18-06-2010)“…The PQBP1 (polyglutamine tract-binding protein 1) gene encodes a nuclear protein that regulates pre-mRNA splicing and transcription. Mutations in the PQBP1…”
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Exploring and profiling protein function with peptide arrays
Published in Methods in molecular biology (Clifton, N.J.) (2009)“…Development of array technologies started in the late 1980s and was first extensively applied to DNA arrays especially in the genomic field. Today this…”
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