Search Results - "Tapia, Julio C."
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Protein Kinase CK2 in Cancer Energetics
Published in Frontiers in oncology (18-06-2020)“…Protein kinase CK2 (formerly known as casein kinase 2) is abnormally elevated in many cancers. This may increase tumor aggressiveness through CK2-dependent…”
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Association of FANCM Mutations with Familial and Early-Onset Breast Cancer Risk in a South American Population
Published in International journal of molecular sciences (01-02-2023)“…Breast cancer (BC) is the most common cancer among women worldwide. are responsible for 16-20% of the risk for hereditary BC. Other susceptibility genes have…”
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A Single Variant in Pri-miRNA-155 Associated with Susceptibility to Hereditary Breast Cancer Promotes Aggressiveness in Breast Cancer Cells
Published in International journal of molecular sciences (06-12-2022)“…Variants in genes encoding for microRNAs have been associated with their deregulation in breast cancer (BC). Sequencing of microRNAs deregulated in BC was…”
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LINC00662 Promotes Aggressive Traits by Modulating OCT4 Expression through miR-335-5p in Gallbladder Cancer Cells
Published in International journal of molecular sciences (19-06-2024)“…Long non-coding RNAs (lncRNAs) are nucleotide sequences that participate in different biological processes and are associated with different pathologies,…”
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TRPM4 regulates Akt/GSK3‐β activity and enhances β‐catenin signaling and cell proliferation in prostate cancer cells
Published in Molecular oncology (01-02-2018)“…Increased expression of the TRPM4 channel has been reported to be associated with the progression of prostate cancer. However, the molecular mechanism…”
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Association of Germline Variation in Driver Genes with Breast Cancer Risk in Chilean Population
Published in International journal of molecular sciences (01-11-2023)“…Cancer is a genomic disease, with driver mutations contributing to tumorigenesis. These potentially heritable variants influence risk and underlie familial…”
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The cancer-related transcription factor Runx2 modulates cell proliferation in human osteosarcoma cell lines
Published in Journal of cellular physiology (01-04-2013)“…Runx2 regulates osteogenic differentiation and bone formation, but also suppresses pre‐osteoblast proliferation by affecting cell cycle progression in the G1…”
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Genetic Variation in MicroRNA-423 Promotes Proliferation, Migration, Invasion, and Chemoresistance in Breast Cancer Cells
Published in International journal of molecular sciences (29-12-2021)“…MicroRNA-423 (miR-423) is highly expressed in breast cancer (BC). Previously, our group showed that the SNP rs6505162:C>A located in the pre-miR-423 was…”
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Effect of Melatonin on Chemoresistance Exhibited by Spheres Derived from Canine Mammary Carcinoma Cells
Published in Animals (Basel) (01-04-2024)“…Mammary cancer is a frequent disease in female dogs, where a high proportion of cases correspond to malignant tumors that may exhibit drug resistance. Within…”
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Tobacco Exposure Enhances Human Papillomavirus 16 Oncogene Expression via EGFR/PI3K/Akt/c-Jun Signaling Pathway in Cervical Cancer Cells
Published in Frontiers in microbiology (17-12-2018)“…High-risk human papillomavirus (HR-HPV) infection is not a sufficient condition for cervical cancer development because most infections are benign and…”
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Cisplatin-resistance and aggressiveness are enhanced by a highly stable endothelin-converting enzyme-1c in lung cancer cells
Published in Biological research (24-10-2024)“…Lung cancer constitutes the leading cause of cancer mortality. High levels of endothelin-1 (ET-1), its cognate receptor ET R and its activating enzyme, the…”
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Heritable genomic diversity in breast cancer driver genes and associations with risk in a Chilean population
Published in Biological research (31-05-2022)“…Driver mutations are the genetic components responsible for tumor initiation and progression. These variants, which may be inherited, influence cancer risk and…”
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Targeting the Endothelin-1 pathway to reduce invasion and chemoresistance in gallbladder cancer cells
Published in Cancer cell international (10-12-2023)“…Gallbladder cancer (GBC) is a prevalent and deadly biliary tract carcinoma, often diagnosed at advanced stages with limited treatment options. The 5-year…”
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Endothelin‐converting enzyme‐1c promotes stem cell traits and aggressiveness in colorectal cancer cells
Published in Molecular oncology (01-02-2020)“…Endothelin‐1 is a mitogenic peptide that activates several proliferation, survival, and invasiveness pathways. The effects of endothelin‐1 rely on its…”
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In Vitro Identification of Phosphorylation Sites on TcPolβ by Protein Kinases TcCK1, TcCK2, TcAUK1, and TcPKC1 and Effect of Phorbol Ester on Activation by TcPKC of TcPolβ in Trypanosoma cruzi Epimastigotes
Published in Microorganisms (Basel) (01-05-2024)“…Chagas disease is caused by the single-flagellated protozoan , which affects several million people worldwide. Understanding the signal transduction pathways…”
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Silver(I) Recovery by Ion Flotation Process from Aqueous Solutions in Cells with Spargers
Published in Minerals (Basel) (01-04-2023)“…Extractive metallurgy has recently turned its attention to waste treatment for the recovery of precious metals through innovative metallurgical processes, such…”
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Cancer Stem Cell and Aggressiveness Traits Are Promoted by Stable Endothelin-Converting Enzyme-1c in Glioblastoma Cells
Published in Cells (Basel, Switzerland) (01-02-2023)“…Glioblastoma (GBM) is the most common and aggressive type of brain tumor due to its elevated recurrence following treatments. This is mainly mediated by a…”
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Indomethacin Induces Spermidine/Spermine-N1-Acetyltransferase-1 via the Nucleolin-CDK1 Axis and Synergizes with the Polyamine Oxidase Inhibitor Methoctramine in Lung Cancer Cells
Published in Biomolecules (Basel, Switzerland) (12-09-2023)“…Indomethacin is a non-selective NSAID used against pain and inflammation. Although cyclooxygenase (COX) inhibition is considered indomethacin’s primary action…”
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E-Cadherin Is Required for Caveolin-1-Mediated Down-Regulation of the Inhibitor of Apoptosis Protein Survivin via Reduced β-Catenin-Tcf/Lef-Dependent Transcription
Published in Molecular and Cellular Biology (01-11-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Colon cancer cell invasion is promoted by protein kinase CK2 through increase of endothelin-converting enzyme-1c protein stability
Published in Oncotarget (15-12-2015)“…Endothelin-converting enzyme-1c (ECE-1c) is a membrane metalloprotease involved in endothelin-1 synthesis, which has been shown in vitro to have a role in…”
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