Search Results - "Tapescu, Iulia"

DDX56 Binds to Chikungunya Virus RNA To Control Infection by Taschuk, Frances, Tapescu, Iulia, Moy, Ryan H., Cherry, Sara

“…Arthropod-borne viruses are diverse pathogens and include the emerging virus chikungunya virus, which is associated with human disease. Through genetic…”
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SARS-CoV-2 ORF6 protein does not antagonize interferon signaling in respiratory epithelial Calu-3 cells during infection by Li, Minghua, Ayyanathan, Kasirajan, Dittmar, Mark, Miller, Jesse, Tapescu, Iulia, Lee, Jae Seung, McGrath, Marisa E, Xue, Yong, Vashee, Sanjay, Schultz, David C, Frieman, Matthew B, Cherry, Sara

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of deaths, posing a substantial threat to global public health. Viruses evolve…”
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Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling by Mallory, Michael J., Allon, Samuel J., Qiu, Jinsong, Gazzara, Matthew R., Tapescu, Iulia, Martinez, Nicole M., Fu, Xiang-Dong, Lynch, Kristen W.

“…Studies in several cell types have highlighted dramatic and diverse changes in mRNA processing that occur upon cellular stimulation. However, the mechanisms…”
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The transformative potential of mRNA vaccines for glioblastoma and human cancer: technological advances and translation to clinical trials by Tapescu, Iulia, Madsen, Peter J, Lowenstein, Pedro R, Castro, Maria G, Bagley, Stephen J, Fan, Yi, Brem, Steven

“…Originally devised for cancer control, mRNA vaccines have risen to the forefront of medicine as effective instruments for control of infectious disease,…”
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Global analysis of physical and functional RNA targets of hnRNP L reveals distinct sequence and epigenetic features of repressed and enhanced exons by Cole, Brian S, Tapescu, Iulia, Allon, Samuel J, Mallory, Michael J, Qiu, Jinsong, Lake, Robert J, Fan, Hua-Ying, Fu, Xiang-Dong, Lynch, Kristen W

“…HnRNP L is a ubiquitous splicing-regulatory protein that is critical for the development and function of mammalian T cells. Previous work has identified a few…”
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DDX RNA helicases: key players in cellular homeostasis and innate antiviral immunity by Tapescu, Iulia, Cherry, Sara

“…RNA helicases are integral in RNA metabolism, performing important roles in cellular homeostasis and stress responses. In particular, the DExD/H-box (DDX)…”
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Thyroid Malignancies With Thymic Differentiation: Outcomes of Rare SETTLE and CASTLE Tumors by Tapescu, Iulia, Kohler, Abigail, Sangal, Neel R., Brant, Jason A., Brody, Robert M., Chao, Timothy, Carey, Ryan M.

“…Spindle epithelial tumors with thymus-like differentiation (SETTLE) and carcinomas showing thymus-like differentiation (CASTLE) are rare intrathyroid…”
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The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection by Tapescu, Iulia, Taschuk, Frances, Pokharel, Swechha M, Zginnyk, Oleksandr, Ferretti, Max, Bailer, Peter F, Whig, Kanupryia, Madden, Emily A, Heise, Mark T, Schultz, David C, Cherry, Sara

“…Alphaviruses are a large group of re-emerging arthropod-borne RNA viruses. The compact viral RNA genomes harbor diverse structures that facilitate replication…”
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TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells by Yarosh, Christopher A, Tapescu, Iulia, Thompson, Matthew G, Qiu, Jinsong, Mallory, Michael J, Fu, Xiang-Dong, Lynch, Kristen W

“…PSF (a.k.a. SFPQ) is a ubiquitously expressed, essential nuclear protein with important roles in DNA damage repair and RNA biogenesis. In stimulated T cells,…”
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Stat1 stimulates cap-independent mRNA translation to inhibit cell proliferation and promote survival in response to antitumor drugs by Wang, Shuo, Patsis, Christos, Koromilas, Antonis E.

“…The signal transducer and activator of transcription 1 (Stat1) functions as a tumor suppressor via immune regulatory and cell-autonomous pathways. Herein, we…”
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