Search Results - "Tao, Yongfeng"
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A proteome-wide atlas of lysine-reactive chemistry
Published in Nature chemistry (01-11-2021)“…Recent advances in chemical proteomics have begun to characterize the reactivity and ligandability of lysines on a global scale. Yet, only a limited diversity…”
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Three-Stream Convolutional Neural Network for Depression Detection With Ocular Imaging
Published in IEEE transactions on neural systems and rehabilitation engineering (2023)“…Depression is a prevalent and severe mental disorder that significantly affects both mind and body, leading to persistent feelings of sadness, despair, and…”
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Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A
Published in Scientific reports (20-05-2021)“…The epithelial–mesenchymal transition (EMT) imparts properties of cancer stem-like cells, including resistance to frequently used chemotherapies, necessitating…”
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Monosialoganglioside (GM1) Attenuates Spinal Cord Injury-Induced Inflammation by Inhibiting TLR4/NF-κB Pathway
Published in Neurochemical journal (01-04-2021)“…This study aims to evaluate the effect of Monosialoganglioside (GM1) on inflammation after spinal cord injury (SCI), and to explore the underlying mechanism…”
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Depressive semantic awareness from vlog facial and vocal streams via spatio-temporal transformer
Published in Digital communications and networks (01-06-2024)“…With the rapid growth of information transmission via the Internet, efforts have been made to reduce network load to promote efficiency. One such application…”
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Publisher Correction: A proteome-wide atlas of lysine-reactive chemistry
Published in Nature chemistry (01-11-2021)Get full text
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A Novel Early-Stage Lung Adenocarcinoma Prognostic Model Based on Feature Selection With Orthogonal Regression
Published in Frontiers in cell and developmental biology (08-01-2021)“…Carcinoma diagnosis and prognosis are still hindered by the lack of effective prediction model and integration methodology. We proposed a novel feature…”
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DepMSTAT: Multimodal Spatio-Temporal Attentional Transformer for Depression Detection
Published in IEEE transactions on knowledge and data engineering (01-07-2024)“…Depression is one of the most common mental illnesses, but few of the currently proposed in-depth models based on social media data take into account both…”
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Detecting depression based on facial cues elicited by emotional stimuli in video
Published in Computers in biology and medicine (01-10-2023)“…Recently, depression research has received considerable attention and there is an urgent need for objective and validated methods to detect depression…”
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Trial Selection Tensor Canonical Correlation Analysis (TSTCCA) for Depression Recognition with Facial Expression and Pupil Diameter
Published in IEEE journal of biomedical and health informatics (05-10-2023)“…Facial expressions have been widely used for depression recognition because it is intuitive and convenient to access. Pupil diameter contains rich emotional…”
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Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1
Published in Journal of the American Chemical Society (12-10-2022)“…Targeted protein degradation induced by heterobifunctional compounds and molecular glues presents an exciting avenue for chemical probe and drug discovery. To…”
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Therapeutic vulnerabilities of cancer stem cells and effects of natural products
Published in Natural product reports (16-08-2023)“…Covering: 1995 to 2022Tumors possess both genetic and phenotypic heterogeneity leading to the survival of subpopulations post-treatment. The term cancer stem…”
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Multimodal Depression Detection Based on Self-Attention Network With Facial Expression and Pupil
Published in IEEE transactions on computational social systems (26-06-2024)“…Depression is a major mental health issue in contemporary society, with an estimated 350 million people affected globally. The number of individuals diagnosed…”
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Behavioral Information Feedback With Large Language Models for Mental Disorders: Perspectives and Insights
Published in IEEE transactions on computational social systems (01-06-2024)“…This edition of the publication includes a robust collection of 104 regular papers and features a Special Issue on Knowledge- Infused Learning for…”
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Total Synthesis and Anticancer Activity of (+)‐Hypercalin C and Congeners
Published in Angewandte Chemie International Edition (25-02-2019)“…The hypercalins are dearomatized acylphloroglucinols with a pendant complex cyclopentane ring that exhibit activity against several cancer cell lines. We…”
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Pharmacophore-Directed Retrosynthesis Applied to Ophiobolin A: Simplified Bicyclic Derivatives Displaying Anticancer Activity
Published in Organic letters (06-11-2020)“…Pharmacophore-directed retrosynthesis applied to ophiobolin A led to bicyclic derivatives that were synthesized and display anticancer activity. Key features…”
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Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2
Published in Angewandte Chemie International Edition (18-12-2023)“…5‐Methylcytosine (m5C) is an RNA modification prevalent on tRNAs, where it can protect tRNAs from endonucleolytic cleavage to maintain protein synthesis. The…”
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Proteomic Ligandability Maps of Spirocycle Acrylamide Stereoprobes Identify Covalent ERCC3 Degraders
Published in Journal of the American Chemical Society (17-04-2024)“…Covalent chemistry coupled with activity-based protein profiling (ABPP) offers a versatile way to discover ligands for proteins in native biological systems…”
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Heck-type cross-coupling between halo-exo-glycals and endo-glycals: a practical way to achieve C-glycosidic disaccharides
Published in Tetrahedron letters (06-11-2013)“…An effective Heck-type cross-coupling reaction between halo-exo-glycals and endo-glycals to achieve C-glycosidic disaccharides has been developed. Using…”
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