Search Results - "Tao, Yizhi"
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Collagen and actin network mediate antiviral immunity against Orsay virus in C. elegans intestinal cells
Published in PLoS pathogens (01-01-2024)“…C. elegans is a free-living nematode that is widely used as a small animal model for studying fundamental biological processes and disease mechanisms. Since…”
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A bacterial transcription activator dedicated to the expression of the enzyme catalyzing the first committed step in fatty acid biosynthesis
Published in Nucleic acids research (30-10-2024)“…Acetyl-CoA carboxylase (ACCase) catalyzes the first committed and rate-limiting step of de novo fatty acid synthesis (FAS). Although this step is tightly…”
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3
Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation
Published in Cell host & microbe (08-11-2017)“…TRIM25 is an E3 ubiquitin ligase that activates RIG-I to promote the antiviral interferon response. The NS1 protein from all strains of influenza A virus binds…”
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4
Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus
Published in PLoS pathogens (14-04-2016)“…During the replication cycle of double-stranded (ds) RNA viruses, the viral RNA-dependent RNA polymerase (RdRP) replicates and transcribes the viral genome…”
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Structural Insights into the Human Astrovirus Capsid
Published in Viruses (01-05-2021)“…Astroviruses (AstVs) are non-enveloped, positive single-stranded RNA viruses that cause a wide range of inflammatory diseases in mammalian and avian hosts. The…”
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6
Bacterial TANGO2 homologs are heme-trafficking proteins that facilitate biosynthesis of cytochromes c
Published in mBio (31-08-2023)“…Heme, an essential molecule for virtually all living organisms, acts primarily as a cofactor in a large number of proteins. However, how heme is mobilized from…”
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Q493K and Q498H substitutions in Spike promote adaptation of SARS-CoV-2 in mice
Published in EBioMedicine (01-05-2021)“…An ideal animal model to study SARS-coronavirus 2 (SARS-CoV-2) pathogenesis and evaluate therapies and vaccines should reproduce SARS-CoV-2 infection and…”
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Orsay δ Protein Is Required for Nonlytic Viral Egress
Published in Journal of virology (15-07-2018)“…Nonenveloped gastrointestinal viruses, such as human rotavirus, can exit infected cells from the apical surface without cell lysis. The mechanism of such…”
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Functional Irreplaceability of Escherichia coli and Shewanella oneidensis OxyRs Is Critically Determined by Intrinsic Differences in Oligomerization
Published in mBio (22-02-2022)“…LysR-type transcriptional regulators (LTTRs), which function in diverse biological processes in prokaryotes, are composed of a conserved structure with an…”
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10
The crystal structure and RNA-binding of an orthomyxovirus nucleoprotein
Published in PLoS pathogens (01-09-2013)“…Genome packaging for viruses with segmented genomes is often a complex problem. This is particularly true for influenza viruses and other orthomyxoviruses,…”
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11
Structural Insights into Charge Pair Interactions in Triple Helical Collagen-like Proteins
Published in The Journal of biological chemistry (09-03-2012)“…The collagen triple helix is the most abundant protein fold in humans. Despite its deceptively simple structure, very little is understood about its folding…”
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12
Variations outside the conserved motifs of PB1 catalytic active site may affect replication efficiency of the RNP complex of influenza A virus
Published in Virology (New York, N.Y.) (01-07-2021)“…PB1 functions as the catalytic subunit of influenza virus RNA polymerase complex and plays an essential role in viral RNA transcription and replication. To…”
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13
Crystal Structure of the Human Astrovirus Capsid Protein
Published in Journal of virology (15-10-2016)“…Human astrovirus (HAstV) is a leading cause of viral diarrhea in infants and young children worldwide. HAstV is a nonenveloped virus with a T=3 capsid and a…”
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14
Assembly of a three-protein complex on DNA probed by nanofluidic stretching
Published in Biophysical journal (10-02-2023)Get full text
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15
The Sialyl Lewis X Glycan Receptor Facilitates Infection of Subtype H7 Avian Influenza A Viruses
Published in Journal of virology (12-10-2022)“…Subtype H7 avian influenza A viruses (IAVs) are enzootic in wild aquatic birds and have caused sporadic spillovers into domestic poultry and humans. Here, we…”
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Characterization of the interaction between the cohesin subunits Rad21 and SA1/2
Published in PloS one (12-07-2013)“…The cohesin complex is responsible for the fidelity of chromosomal segregation during mitosis. It consists of four core subunits, namely Rad21/Mcd1/Scc1, Smc1,…”
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Structure of a pentameric virion-associated fiber with a potential role in Orsay virus entry to host cells
Published in PLoS pathogens (01-02-2017)“…Despite the wide use of Caenorhabditis elegans as a model organism, the first virus naturally infecting this organism was not discovered until six years ago…”
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18
Triple reassortment increases compatibility among viral ribonucleoprotein genes of contemporary avian and human influenza A viruses
Published in PLoS pathogens (01-10-2021)“…Compatibility among the influenza A virus (IAV) ribonucleoprotein (RNP) genes affects viral replication efficiency and can limit the emergence of novel…”
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19
The Differential Cytotoxicity of Water-Soluble Fullerenes
Published in Nano letters (01-10-2004)“…We show that the cytotoxicity of water-soluble fullerene species is a sensitive function of surface derivatization; in two different human cell lines, the…”
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20
Crystal structure of the human astrovirus capsid spike
Published in Proceedings of the National Academy of Sciences - PNAS (02-08-2011)“…Astroviruses are single-stranded, plus-sense RNA viruses that infect both mammals and birds, causing gastroenteritis and other extraintestinal diseases…”
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