Search Results - "Tao, Xiaoan"
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Current Understanding of IL-37 in Human Health and Disease
Published in Frontiers in immunology (25-06-2021)“…IL-37 is a recently discovered cytokine in the IL-1 family exerting broad protective effects on inflammatory diseases, autoimmune diseases, and cancer. Immune…”
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Epithelial‐to‐mesenchymal transition in oral squamous cell carcinoma: Challenges and opportunities
Published in International journal of cancer (01-04-2021)“…Oral squamous cell carcinoma (OSCC) is the most common malignancy representing 90% of all forms of oral cancer worldwide. Although great efforts have been made…”
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AP1G1 is involved in cetuximab-mediated downregulation of ASCT2-EGFR complex and sensitization of human head and neck squamous cell carcinoma cells to ROS-induced apoptosis
Published in Cancer letters (01-11-2017)“…In this study, we expanded our recent work showing that ASCT2, a Na+-dependent neutral amino acid transporter that plays a major role in glutamine uptake in…”
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Efficacy and safety of topical administration of tacrolimus in oral lichen planus: An updated systematic review and meta‐analysis of randomized controlled trials
Published in Journal of oral pathology & medicine (01-01-2022)“…Background Symptomatic oral lichen planus is a common chronic T‐cell‐mediated disorder characterized by pain and inflammation. The meta‐analysis aimed to…”
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LncRNA-p23154 promotes the invasion-metastasis potential of oral squamous cell carcinoma by regulating Glut1-mediated glycolysis
Published in Cancer letters (10-10-2018)“…The dysregulation of glycolysis has been suggested to lead to alteration of cell drug resistance signals, proliferation and metastasis. Emerging evidence…”
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Diet-induced obesity accelerates oral carcinogenesis by recruitment and functional enhancement of myeloid-derived suppressor cells
Published in Cell death & disease (14-10-2021)“…Although obesity has been associated with an increased risk and aggressiveness of many types of carcinoma, whether it promotes squamous cell carcinoma remains…”
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Glutamine promotes the proliferation of epithelial cells via mTOR/S6 pathway in oral lichen planus
Published in Journal of oral pathology & medicine (01-02-2023)“…Background Although abnormal cell proliferation and apoptosis are associated with the pathogenesis of oral lichen planus (OLP), the exactly mechanism of which…”
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Targeting CCL2-CCR4 axis suppress cell migration of head and neck squamous cell carcinoma
Published in Cell death & disease (17-02-2022)“…For head and neck squamous cell carcinoma (HNSCC), the local invasion and distant metastasis represent the predominant causes of mortality. Targeted inhibition…”
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Chemokine (CC motif) ligand 18 upregulates Slug expression to promote stem‐cell like features by activating the mammalian target of rapamycin pathway in oral squamous cell carcinoma
Published in Cancer science (01-08-2017)“…Chemokine (CC motif) ligand 18 (CCL18) is involved in remodeling of the tumor microenvironment and plays critical roles in oncogenesis, invasiveness, and…”
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CCL2 promotes cell migration by inducing epithelial‐mesenchymal transition in oral squamous cell carcinoma
Published in Journal of oral pathology & medicine (01-07-2019)“…Background Although a few studies suggested that the chemokine CCL2 might be involved in the development of oral squamous cell carcinoma (OSCC), the exact…”
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TLR‐4 targeting contributes to the recovery of osteoimmunology in periodontitis
Published in Journal of periodontal research (01-08-2021)“…Objective The aim of this study was to determine the potential role of TLR‐4 in the osteoimmunological imbalance of periodontitis. Background Although current…”
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Retinoids in cancer chemoprevention and therapy: Meta-analysis of randomized controlled trials
Published in Frontiers in genetics (09-11-2022)“…Retinoids, natural and synthetic derivatives of vitamin A, have many regulatory functions in human body, including regulating cellular proliferation,…”
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Combined class I histone deacetylase and mTORC1/C2 inhibition suppresses the initiation and recurrence of oral squamous cell carcinomas by repressing SOX2
Published in Cancer letters (10-07-2019)“…Treatment of oral squamous cell carcinoma (OSCC) remains a challenge because of the lack of effective early treatment strategies and high incidence of relapse…”
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Splice site m6A methylation prevents binding of DGCR8 to suppress KRT4 pre-mRNA splicing in oral squamous cell carcinoma
Published in PeerJ (San Francisco, CA) (16-02-2023)“…Oral squamous cell carcinoma (OSCC) is the 11th most prevalent tumor worldwide. Despite advantages of therapeutic approaches, the 5-year survival rate of…”
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Targeting methyltransferase PRMT5 retards the carcinogenesis and metastasis of HNSCC via epigenetically inhibiting Twist1 transcription
Published in Neoplasia (New York, N.Y.) (01-11-2020)“…Protein arginine methyltransferase 5 (PRMT5) is an important type II arginine methyltransferase that can play roles in cancers in a highly tissue-specific…”
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Oxidative stress promotes oral carcinogenesis via Thbs1-mediated M1-like tumor-associated macrophages polarization
Published in Redox biology (01-10-2024)“…Although oxidative stress is closely associated with tumor invasion and metastasis, its’ exact role and mechanism in the initial stage of oral cancer remain…”
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Overexpression of miR-155 promotes the proliferation and invasion of oral squamous carcinoma cells by regulating BCL6/cyclin D2
Published in International journal of molecular medicine (01-05-2016)“…Although microRNA-155 (miR-155) is known to play an important role in many cancers, its expression and function in oral squamous cell carcinoma (OSCC) was not…”
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ASCT2 overexpression is associated with poor survival of OSCC patients and ASCT2 knockdown inhibited growth of glutamine‐addicted OSCC cells
Published in Cancer medicine (Malden, MA) (01-05-2020)“…Background Alanine‐serine‐cysteine transporter 2 (ASCT2), a major glutamine transporter, is essential for cell growth and tumor development in a variety of…”
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Cellular hierarchy framework based on single-cell/multi-patient sample sequencing reveals metabolic biomarker PYGL as a therapeutic target for HNSCC
Published in Journal of experimental & clinical cancer research (08-07-2023)“…A growing body of research has revealed the connection of metabolism reprogramming and tumor progression, yet how metabolism reprogramming affects…”
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KRT4 suppresses oral squamous cell carcinoma development by reducing ATG4B-mediated autophagy
Published in Biocell (2022)“…Head and neck squamous cell carcinoma is the sixth most common tumor worldwide, and half of head and neck squamous cell carcinoma patients are with oral…”
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